ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	73/304	423/7206	7.14605727232e-27
ko05033	Nicotine addiction	23/304	56/7206	9.46637074992e-18
ko04724	Glutamatergic synapse	31/304	152/7206	1.07278156599e-13
ko04713	Circadian entrainment	23/304	136/7206	8.80543802768e-09
ko04728	Dopaminergic synapse	27/304	185/7206	1.19339698341e-08
ko04727	GABAergic synapse	19/304	110/7206	1.27366147262e-07
ko04742	Taste transduction	14/304	61/7206	1.57219771481e-07
ko05031	Amphetamine addiction	17/304	91/7206	1.83523698157e-07
ko04723	Retrograde endocannabinoid signaling	24/304	175/7206	2.66345743198e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	15/304	74/7206	3.2331003793e-07
ko04740	Olfactory transduction	15/304	80/7206	9.34780693885e-07
ko05030	Cocaine addiction	14/304	73/7206	1.63223458433e-06
ko05032	Morphine addiction	16/304	110/7206	1.29641998279e-05
ko04730	Long-term depression	12/304	78/7206	9.09199818621e-05
ko04024	cAMP signaling pathway	26/304	279/7206	0.000175743081941
ko04725	Cholinergic synapse	17/304	160/7206	0.000390153162609
ko04726	Serotonergic synapse	15/304	137/7206	0.000620748908738
ko04720	Long-term potentiation	12/304	99/7206	0.000876407313087
ko04924	Renin secretion	11/304	86/7206	0.000909554474788
ko04514	Cell adhesion molecules (CAMs)	14/304	130/7206	0.00110299533767
ko04744	Phototransduction	6/304	36/7206	0.00358278042983
ko04261	Adrenergic signaling in cardiomyocytes	17/304	205/7206	0.00710163386926
ko04921	Oxytocin signaling pathway	17/304	209/7206	0.00811843308617
ko03013	RNA transport	1/304	166/7206	0.0103364368953
ko04550	Signaling pathways regulating pluripotency of stem cells	1/304	165/7206	0.0103418348211
ko05164	Influenza A	1/304	167/7206	0.0103510444948
ko04020	Calcium signaling pathway	20/304	265/7206	0.0114821852673
ko05203	Viral carcinogenesis	4/304	277/7206	0.014008928659
ko04140	Autophagy - animal	1/304	164/7206	0.0158070190985
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	8/304	79/7206	0.017728681435
ko04970	Salivary secretion	9/304	95/7206	0.0183523418
ko04721	Synaptic vesicle cycle	8/304	80/7206	0.0190030217136
ko04976	Bile secretion	8/304	80/7206	0.0190030217136
ko05205	Proteoglycans in cancer	4/304	271/7206	0.0194215607499
ko05200	Pathways in cancer	11/304	492/7206	0.0198565162336
ko04142	Lysosome	1/304	151/7206	0.0219659654095
ko04260	Cardiac muscle contraction	9/304	98/7206	0.0220437395481
ko04010	MAPK signaling pathway	22/304	321/7206	0.0222530950854
ko05166	HTLV-I infection	5/304	292/7206	0.0250733100701
ko05152	Tuberculosis	2/304	187/7206	0.025118709835
ko04060	Cytokine-cytokine receptor interaction	2/304	191/7206	0.0258983024846
ko00830	Retinol metabolism	5/304	42/7206	0.0306503954354
ko04120	Ubiquitin mediated proteolysis	1/304	138/7206	0.0311465154525
ko04919	Thyroid hormone signaling pathway	1/304	143/7206	0.0320670594083
ko03040	Spliceosome	1/304	145/7206	0.0328090452956
ko04110	Cell cycle	1/304	145/7206	0.0328090452956
ko05161	Hepatitis B	2/304	173/7206	0.0349052466965
ko05206	MicroRNAs in cancer	2/304	177/7206	0.0351692771662
ko04218	Cellular senescence	2/304	177/7206	0.0351692771662
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/304	182/7206	0.0365359547259
ko05410	Hypertrophic cardiomyopathy (HCM)	9/304	100/7206	0.0378091691148
ko04614	Renin-angiotensin system	3/304	18/7206	0.0379139292374
ko04933	AGE-RAGE signaling pathway in diabetic complications	1/304	135/7206	0.0468288448799
ko04068	FoxO signaling pathway	2/304	167/7206	0.0490731347089