ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	156/1039	423/7206	1.06553659754e-32
ko04724	Glutamatergic synapse	78/1039	152/7206	1.67142412521e-27
ko05033	Nicotine addiction	43/1039	56/7206	9.05768816896e-26
ko04721	Synaptic vesicle cycle	52/1039	80/7206	2.9761958596e-25
ko04727	GABAergic synapse	57/1039	110/7206	1.23490390248e-20
ko04728	Dopaminergic synapse	77/1039	185/7206	5.5366504705e-20
ko05032	Morphine addiction	56/1039	110/7206	8.16000580426e-20
ko04713	Circadian entrainment	63/1039	136/7206	2.07144065851e-19
ko04725	Cholinergic synapse	67/1039	160/7206	1.09312942447e-17
ko04723	Retrograde endocannabinoid signaling	67/1039	175/7206	2.56654322825e-15
ko04024	cAMP signaling pathway	89/1039	279/7206	4.20737364605e-14
ko04742	Taste transduction	32/1039	61/7206	2.52720686451e-12
ko04726	Serotonergic synapse	52/1039	137/7206	5.46932493237e-12
ko04911	Insulin secretion	47/1039	117/7206	5.51457606141e-12
ko04744	Phototransduction	22/1039	36/7206	1.28467618941e-10
ko04921	Oxytocin signaling pathway	64/1039	209/7206	1.28674817245e-09
ko04261	Adrenergic signaling in cardiomyocytes	63/1039	205/7206	1.69816570189e-09
ko05031	Amphetamine addiction	36/1039	91/7206	2.85011206526e-09
ko03040	Spliceosome	1/1039	145/7206	5.65073914566e-09
ko04360	Axon guidance	66/1039	233/7206	2.09047298177e-08
ko04720	Long-term potentiation	36/1039	99/7206	3.912977761e-08
ko05168	Herpes simplex infection	5/1039	182/7206	1.62500323335e-07
ko04966	Collecting duct acid secretion	15/1039	26/7206	3.55905786117e-07
ko04020	Calcium signaling pathway	69/1039	265/7206	4.18001409818e-07
ko05203	Viral carcinogenesis	14/1039	277/7206	7.38463682753e-07
ko04740	Olfactory transduction	29/1039	80/7206	8.85818714292e-07
ko03013	RNA transport	5/1039	166/7206	1.61215825141e-06
ko04060	Cytokine-cytokine receptor interaction	7/1039	191/7206	1.68965243039e-06
ko04120	Ubiquitin mediated proteolysis	3/1039	138/7206	1.83647265632e-06
ko04970	Salivary secretion	32/1039	95/7206	1.94338452253e-06
ko05030	Cocaine addiction	26/1039	73/7206	4.73470224374e-06
ko05164	Influenza A	6/1039	167/7206	5.84501270886e-06
ko04925	Aldosterone synthesis and secretion	32/1039	105/7206	1.87027409204e-05
ko04621	NOD-like receptor signaling pathway	6/1039	157/7206	2.54738435462e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1039	79/7206	2.82777119242e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	25/1039	74/7206	3.00139589799e-05
ko04971	Gastric acid secretion	30/1039	98/7206	3.25088564814e-05
ko04141	Protein processing in endoplasmic reticulum	9/1039	184/7206	4.41457422442e-05
ko04010	MAPK signaling pathway	72/1039	321/7206	8.49033974113e-05
ko04260	Cardiac muscle contraction	29/1039	98/7206	0.00011063510499
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/1039	59/7206	0.000129908282332
ko03008	Ribosome biogenesis in eukaryotes	1/1039	79/7206	0.000132970523452
ko04924	Renin secretion	26/1039	86/7206	0.000143678470314
ko05322	Systemic lupus erythematosus	7/1039	151/7206	0.000151909070835
ko05205	Proteoglycans in cancer	19/1039	271/7206	0.000191623049602
ko04514	Cell adhesion molecules (CAMs)	35/1039	130/7206	0.00019898748024
ko00604	Glycosphingolipid biosynthesis - ganglio series	8/1039	14/7206	0.000243043907156
ko04964	Proximal tubule bicarbonate reclamation	12/1039	29/7206	0.000365596340182
ko05169	Epstein-Barr virus infection	13/1039	206/7206	0.000378871977574
ko04745	Phototransduction - fly	14/1039	38/7206	0.000503316929271
ko04730	Long-term depression	23/1039	78/7206	0.000511454326566
ko04022	cGMP-PKG signaling pathway	50/1039	216/7206	0.000517294976582
ko04972	Pancreatic secretion	30/1039	111/7206	0.000524293057635
ko05162	Measles	5/1039	120/7206	0.000533261579678
ko04064	NF-kappa B signaling pathway	3/1039	96/7206	0.000591266318308
ko04640	Hematopoietic cell lineage	1/1039	64/7206	0.000979818137638
ko04976	Bile secretion	23/1039	80/7206	0.00104013001025
ko04110	Cell cycle	8/1039	145/7206	0.00111194531307
ko04540	Gap junction	32/1039	128/7206	0.00133808257746
ko05161	Hepatitis B	11/1039	173/7206	0.00135136755963
ko05140	Leishmaniasis	2/1039	75/7206	0.00138044210209
ko05414	Dilated cardiomyopathy	29/1039	112/7206	0.00153927952213
ko05110	Vibrio cholerae infection	19/1039	63/7206	0.00161646397117
ko00480	Glutathione metabolism	1/1039	55/7206	0.00325376352849
ko00590	Arachidonic acid metabolism	1/1039	52/7206	0.00485053221682
ko05166	HTLV-I infection	26/1039	292/7206	0.00489387781721
ko01200	Carbon metabolism	8/1039	128/7206	0.00507806251134
ko04014	Ras signaling pathway	57/1039	279/7206	0.00524167492601
ko04915	Estrogen signaling pathway	31/1039	131/7206	0.00526520453319
ko04657	IL-17 signaling pathway	4/1039	87/7206	0.00530333705658
ko04146	Peroxisome	4/1039	89/7206	0.00552378295777
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/1039	182/7206	0.00724132600045
ko03018	RNA degradation	4/1039	84/7206	0.00743827343538
ko00330	Arginine and proline metabolism	2/1039	61/7206	0.00916758951921
ko04626	Plant-pathogen interaction	7/1039	18/7206	0.00944869794597
ko04930	Type II diabetes mellitus	15/1039	54/7206	0.00990817789935
ko04214	Apoptosis - fly	3/1039	72/7206	0.0102420143784
ko03420	Nucleotide excision repair	1/1039	46/7206	0.0107514396868
ko00240	Pyrimidine metabolism	7/1039	110/7206	0.0131234394201
ko04070	Phosphatidylinositol signaling system	26/1039	112/7206	0.0137021763044
ko03022	Basal transcription factors	1/1039	44/7206	0.0161003760084
ko00071	Fatty acid degradation	1/1039	45/7206	0.016633317544
ko00280	Valine, leucine and isoleucine degradation	2/1039	54/7206	0.0188130009199
ko04750	Inflammatory mediator regulation of TRP channels	27/1039	122/7206	0.0188912338568
ko05321	Inflammatory bowel disease (IBD)	2/1039	56/7206	0.0196357059094
ko05410	Hypertrophic cardiomyopathy (HCM)	23/1039	100/7206	0.0206865418138
ko04612	Antigen processing and presentation	4/1039	77/7206	0.020742845976
ko04391	Hippo signaling pathway - fly	21/1039	90/7206	0.0223358760011
ko04072	Phospholipase D signaling pathway	40/1039	197/7206	0.0230681036582
ko04630	Jak-STAT signaling pathway	10/1039	132/7206	0.0235783177062
ko00980	Metabolism of xenobiotics by cytochrome P450	1/1039	40/7206	0.0237032858605
ko00983	Drug metabolism - other enzymes	1/1039	42/7206	0.0244947485528
ko04668	TNF signaling pathway	9/1039	120/7206	0.025861401382
ko00310	Lysine degradation	4/1039	73/7206	0.0280092348987
ko05418	Fluid shear stress and atherosclerosis	15/1039	173/7206	0.0280897591161
ko04622	RIG-I-like receptor signaling pathway	3/1039	62/7206	0.0281570378573
ko00561	Glycerolipid metabolism	3/1039	63/7206	0.0286149943797
ko00600	Sphingolipid metabolism	3/1039	63/7206	0.0286149943797
ko04923	Regulation of lipolysis in adipocytes	18/1039	77/7206	0.0326640148545
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/1039	92/7206	0.0347581911136
ko00982	Drug metabolism - cytochrome P450	1/1039	37/7206	0.0350945480464
ko03320	PPAR signaling pathway	4/1039	69/7206	0.0382009089721
ko05206	MicroRNAs in cancer	16/1039	177/7206	0.0391685796909
ko05145	Toxoplasmosis	10/1039	126/7206	0.0395669848236
ko00380	Tryptophan metabolism	2/1039	50/7206	0.0401084515265
ko04973	Carbohydrate digestion and absorption	11/1039	42/7206	0.043528676907
ko05133	Pertussis	6/1039	87/7206	0.0450647248588
ko01524	Platinum drug resistance	5/1039	76/7206	0.0488314841657