ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	171/1016	423/7206	1.47745411041e-43
ko04724	Glutamatergic synapse	82/1016	152/7206	1.26848280842e-31
ko05033	Nicotine addiction	43/1016	56/7206	3.5534595417e-26
ko05032	Morphine addiction	60/1016	110/7206	1.03172888832e-23
ko04727	GABAergic synapse	57/1016	110/7206	4.03521365374e-21
ko04713	Circadian entrainment	64/1016	136/7206	1.11559562968e-20
ko04728	Dopaminergic synapse	76/1016	185/7206	6.32526066316e-20
ko04723	Retrograde endocannabinoid signaling	70/1016	175/7206	1.1163505106e-17
ko04725	Cholinergic synapse	65/1016	160/7206	6.74645368662e-17
ko04721	Synaptic vesicle cycle	41/1016	80/7206	2.60647129587e-15
ko04024	cAMP signaling pathway	89/1016	279/7206	1.01051341998e-14
ko04911	Insulin secretion	50/1016	117/7206	2.59720250655e-14
ko04020	Calcium signaling pathway	84/1016	265/7206	8.77056023874e-14
ko04726	Serotonergic synapse	52/1016	137/7206	2.25831964875e-12
ko04921	Oxytocin signaling pathway	68/1016	209/7206	4.95730943545e-12
ko04742	Taste transduction	31/1016	61/7206	9.13768166219e-12
ko04720	Long-term potentiation	40/1016	99/7206	8.64978576854e-11
ko05031	Amphetamine addiction	37/1016	91/7206	3.58220975976e-10
ko04261	Adrenergic signaling in cardiomyocytes	61/1016	205/7206	4.53273420432e-09
ko04360	Axon guidance	66/1016	233/7206	8.22255722157e-09
ko03040	Spliceosome	1/1016	145/7206	9.02443241978e-09
ko05030	Cocaine addiction	28/1016	73/7206	2.2086958209e-07
ko04010	MAPK signaling pathway	79/1016	321/7206	2.69655762193e-07
ko04970	Salivary secretion	33/1016	95/7206	2.91757294225e-07
ko04744	Phototransduction	18/1016	36/7206	3.07392429811e-07
ko03013	RNA transport	4/1016	166/7206	3.87762218455e-07
ko04925	Aldosterone synthesis and secretion	34/1016	105/7206	1.36506529668e-06
ko04072	Phospholipase D signaling pathway	53/1016	197/7206	1.93253741521e-06
ko04971	Gastric acid secretion	32/1016	98/7206	2.40980540615e-06
ko05322	Systemic lupus erythematosus	4/1016	151/7206	2.63665941879e-06
ko04070	Phosphatidylinositol signaling system	35/1016	112/7206	2.93260574057e-06
ko04730	Long-term depression	27/1016	78/7206	3.76907767442e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/1016	74/7206	1.39646596381e-05
ko04514	Cell adhesion molecules (CAMs)	37/1016	130/7206	1.73771846191e-05
ko04060	Cytokine-cytokine receptor interaction	9/1016	191/7206	3.25767698389e-05
ko04014	Ras signaling pathway	64/1016	279/7206	4.77401445564e-05
ko04022	cGMP-PKG signaling pathway	52/1016	216/7206	6.27068696484e-05
ko04120	Ubiquitin mediated proteolysis	5/1016	138/7206	6.36815163435e-05
ko05168	Herpes simplex infection	9/1016	182/7206	8.73139894189e-05
ko04745	Phototransduction - fly	15/1016	38/7206	0.00010016503679
ko04621	NOD-like receptor signaling pathway	7/1016	157/7206	0.000111213946996
ko04972	Pancreatic secretion	31/1016	111/7206	0.000146464797149
ko04612	Antigen processing and presentation	1/1016	77/7206	0.000197541752325
ko04141	Protein processing in endoplasmic reticulum	10/1016	184/7206	0.000229789918389
ko04750	Inflammatory mediator regulation of TRP channels	32/1016	122/7206	0.000332006539524
ko05203	Viral carcinogenesis	20/1016	277/7206	0.00040056356537
ko04966	Collecting duct acid secretion	11/1016	26/7206	0.000419735732044
ko05164	Influenza A	9/1016	167/7206	0.00043259889554
ko04540	Gap junction	33/1016	128/7206	0.000438609119038
ko04710	Circadian rhythm	15/1016	43/7206	0.000493028469573
ko05231	Choline metabolism in cancer	33/1016	134/7206	0.000991331208702
ko04260	Cardiac muscle contraction	26/1016	98/7206	0.00107425102344
ko04915	Estrogen signaling pathway	32/1016	131/7206	0.00137523815773
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/1016	79/7206	0.00156644072957
ko04740	Olfactory transduction	22/1016	80/7206	0.00169791205356
ko04930	Type II diabetes mellitus	16/1016	54/7206	0.00263579935443
ko04110	Cell cycle	9/1016	145/7206	0.00363998439728
ko04924	Renin secretion	22/1016	86/7206	0.00440905767819
ko04964	Proximal tubule bicarbonate reclamation	10/1016	29/7206	0.00466586509372
ko04960	Aldosterone-regulated sodium reabsorption	13/1016	41/7206	0.00501651551869
ko04146	Peroxisome	4/1016	89/7206	0.00538211910169
ko05110	Vibrio cholerae infection	17/1016	63/7206	0.00591902354614
ko05169	Epstein-Barr virus infection	16/1016	206/7206	0.0059728585256
ko05162	Measles	7/1016	120/7206	0.00749906203821
ko04064	NF-kappa B signaling pathway	5/1016	96/7206	0.0076460007406
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1016	14/7206	0.00845141410272
ko05414	Dilated cardiomyopathy	26/1016	112/7206	0.008701103969
ko00310	Lysine degradation	3/1016	73/7206	0.0102242879587
ko04015	Rap1 signaling pathway	54/1016	278/7206	0.0134927313594
ko00562	Inositol phosphate metabolism	21/1016	89/7206	0.0137532271
ko04071	Sphingolipid signaling pathway	34/1016	162/7206	0.0158551206236
ko03022	Basal transcription factors	1/1016	44/7206	0.0161597410934
ko05144	Malaria	1/1016	45/7206	0.0162921123214
ko00071	Fatty acid degradation	1/1016	45/7206	0.0162921123214
ko03420	Nucleotide excision repair	1/1016	46/7206	0.0168180021554
ko05133	Pertussis	5/1016	87/7206	0.0197693184889
ko05161	Hepatitis B	14/1016	173/7206	0.0198277298113
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1016	59/7206	0.0217490469191
ko04012	ErbB signaling pathway	24/1016	109/7206	0.0252023145776
ko04711	Circadian rhythm - fly	5/1016	13/7206	0.0266577838714
ko03018	RNA degradation	5/1016	84/7206	0.026917347732
ko00280	Valine, leucine and isoleucine degradation	2/1016	54/7206	0.0281940415998
ko05140	Leishmaniasis	4/1016	75/7206	0.028450954544
ko04640	Hematopoietic cell lineage	3/1016	64/7206	0.0286521202299
ko04923	Regulation of lipolysis in adipocytes	18/1016	77/7206	0.0302388363569
ko04626	Plant-pathogen interaction	6/1016	18/7206	0.0317969964234
ko03410	Base excision repair	1/1016	38/7206	0.035373632245
ko04214	Apoptosis - fly	4/1016	72/7206	0.0391262419699
ko04932	Non-alcoholic fatty liver disease (NAFLD)	16/1016	182/7206	0.0396616345728
ko00330	Arginine and proline metabolism	3/1016	61/7206	0.0400844085174
ko04973	Carbohydrate digestion and absorption	11/1016	42/7206	0.0407755704546
ko04330	Notch signaling pathway	3/1016	62/7206	0.0410241311333
ko04622	RIG-I-like receptor signaling pathway	3/1016	62/7206	0.0410241311333
ko00910	Nitrogen metabolism	6/1016	19/7206	0.0410961695537
ko04114	Oocyte meiosis	28/1016	139/7206	0.0479203592866
ko04912	GnRH signaling pathway	25/1016	122/7206	0.0482949602886
ko04217	Necroptosis	16/1016	178/7206	0.0491521041754
ko04610	Complement and coagulation cascades	5/1016	79/7206	0.0495454145769