ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	155/868	423/7206	4.27623411891e-42
ko05033	Nicotine addiction	43/868	56/7206	4.70571254348e-29
ko04724	Glutamatergic synapse	67/868	152/7206	1.49185513738e-23
ko04721	Synaptic vesicle cycle	44/868	80/7206	1.32848002512e-20
ko05032	Morphine addiction	51/868	110/7206	2.31916764749e-19
ko04728	Dopaminergic synapse	68/868	185/7206	1.25456621627e-18
ko04727	GABAergic synapse	48/868	110/7206	5.8717428387e-17
ko04713	Circadian entrainment	53/868	136/7206	5.11058596503e-16
ko04725	Cholinergic synapse	56/868	160/7206	1.86360462483e-14
ko04723	Retrograde endocannabinoid signaling	59/868	175/7206	2.48124696051e-14
ko04024	cAMP signaling pathway	77/868	279/7206	6.12279585881e-13
ko04911	Insulin secretion	40/868	117/7206	2.52313453107e-10
ko04360	Axon guidance	61/868	233/7206	1.90775418403e-09
ko04020	Calcium signaling pathway	66/868	265/7206	3.56937323187e-09
ko04726	Serotonergic synapse	42/868	137/7206	4.0266296213e-09
ko04261	Adrenergic signaling in cardiomyocytes	55/868	205/7206	4.95894690465e-09
ko05031	Amphetamine addiction	32/868	91/7206	7.27078953884e-09
ko04921	Oxytocin signaling pathway	55/868	209/7206	8.83654973343e-09
ko04742	Taste transduction	24/868	61/7206	4.69060808528e-08
ko04744	Phototransduction	17/868	36/7206	1.87298952481e-07
ko03040	Spliceosome	1/868	145/7206	2.24001590886e-07
ko05203	Viral carcinogenesis	9/868	277/7206	2.38110231791e-07
ko04970	Salivary secretion	29/868	95/7206	1.15352466168e-06
ko05030	Cocaine addiction	24/868	73/7206	2.23990004967e-06
ko04720	Long-term potentiation	29/868	99/7206	2.93740105942e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/868	74/7206	2.94343335836e-06
ko04060	Cytokine-cytokine receptor interaction	5/868	191/7206	4.31946277881e-06
ko04120	Ubiquitin mediated proteolysis	2/868	138/7206	7.48838807766e-06
ko05168	Herpes simplex infection	5/868	182/7206	8.79718588295e-06
ko05164	Influenza A	4/868	167/7206	1.00911910559e-05
ko04966	Collecting duct acid secretion	12/868	26/7206	1.66482894024e-05
ko04022	cGMP-PKG signaling pathway	48/868	216/7206	1.72800417615e-05
ko03013	RNA transport	5/868	166/7206	5.27551342229e-05
ko04514	Cell adhesion molecules (CAMs)	32/868	130/7206	5.70221321817e-05
ko05322	Systemic lupus erythematosus	4/868	151/7206	6.48225228425e-05
ko04010	MAPK signaling pathway	62/868	321/7206	0.000142338067331
ko04621	NOD-like receptor signaling pathway	5/868	157/7206	0.000155362119951
ko04730	Long-term depression	21/868	78/7206	0.000295822282181
ko05205	Proteoglycans in cancer	15/868	271/7206	0.000388335830305
ko04740	Olfactory transduction	21/868	80/7206	0.000402617825156
ko04971	Gastric acid secretion	24/868	98/7206	0.000494617874617
ko04141	Protein processing in endoplasmic reticulum	8/868	184/7206	0.000497352329487
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/868	14/7206	0.000572695508908
ko04924	Renin secretion	22/868	86/7206	0.00059492314096
ko04972	Pancreatic secretion	26/868	111/7206	0.00063231112125
ko03008	Ribosome biogenesis in eukaryotes	1/868	79/7206	0.000751784365045
ko04612	Antigen processing and presentation	1/868	77/7206	0.00115073269204
ko04260	Cardiac muscle contraction	23/868	98/7206	0.00143618809729
ko05169	Epstein-Barr virus infection	11/868	206/7206	0.00151593925146
ko05162	Measles	4/868	120/7206	0.00156732271469
ko04214	Apoptosis - fly	1/868	72/7206	0.00165963871937
ko04925	Aldosterone synthesis and secretion	24/868	105/7206	0.00207605676788
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/868	79/7206	0.00258803110543
ko05110	Vibrio cholerae infection	16/868	63/7206	0.00289267862554
ko05161	Hepatitis B	9/868	173/7206	0.00298336841594
ko04064	NF-kappa B signaling pathway	3/868	96/7206	0.00392239095074
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/868	59/7206	0.00395197024979
ko04745	Phototransduction - fly	11/868	38/7206	0.00403196734675
ko05166	HTLV-I infection	20/868	292/7206	0.00425193557394
ko04110	Cell cycle	7/868	145/7206	0.00432584577086
ko04964	Proximal tubule bicarbonate reclamation	9/868	29/7206	0.00546248058532
ko04540	Gap junction	26/868	128/7206	0.00597412650517
ko05140	Leishmaniasis	2/868	75/7206	0.00688523313215
ko04146	Peroxisome	3/868	89/7206	0.00786541222119
ko00330	Arginine and proline metabolism	1/868	61/7206	0.00847850170417
ko00310	Lysine degradation	2/868	73/7206	0.0100997672244
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/868	182/7206	0.0105993109038
ko03018	RNA degradation	3/868	84/7206	0.0109557405078
ko00240	Pyrimidine metabolism	5/868	110/7206	0.0114093171056
ko00480	Glutathione metabolism	1/868	55/7206	0.0117835124151
ko05321	Inflammatory bowel disease (IBD)	1/868	56/7206	0.0118855983537
ko04630	Jak-STAT signaling pathway	7/868	132/7206	0.014320367649
ko04014	Ras signaling pathway	47/868	279/7206	0.0146451522681
ko04140	Autophagy - animal	10/868	164/7206	0.0148737949593
ko04626	Plant-pathogen interaction	6/868	18/7206	0.0155137915731
ko00590	Arachidonic acid metabolism	1/868	52/7206	0.017381327894
ko04070	Phosphatidylinositol signaling system	22/868	112/7206	0.0183850787236
ko05414	Dilated cardiomyopathy	22/868	112/7206	0.0183850787236
ko04640	Hematopoietic cell lineage	2/868	64/7206	0.0203848919288
ko05215	Prostate cancer	6/868	111/7206	0.0269581119056
ko00561	Glycerolipid metabolism	2/868	63/7206	0.0298377162948
ko01524	Platinum drug resistance	3/868	76/7206	0.0311139729357
ko04391	Hippo signaling pathway - fly	18/868	90/7206	0.0319370915257
ko04668	TNF signaling pathway	7/868	120/7206	0.0331997265979
ko05418	Fluid shear stress and atherosclerosis	12/868	173/7206	0.0333706860827
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/868	92/7206	0.0346005361767
ko00071	Fatty acid degradation	1/868	45/7206	0.0374584404748
ko04611	Platelet activation	11/868	163/7206	0.0375545114735
ko03420	Nucleotide excision repair	1/868	46/7206	0.037900238044
ko00270	Cysteine and methionine metabolism	1/868	47/7206	0.0389146110421
ko01200	Carbon metabolism	8/868	128/7206	0.0396605669611
ko05220	Chronic myeloid leukemia	4/868	85/7206	0.0418700635442
ko04510	Focal adhesion	19/868	240/7206	0.043760588829
ko05200	Pathways in cancer	45/868	492/7206	0.0441778282336
ko04371	Apelin signaling pathway	30/868	177/7206	0.0468175369252
ko04217	Necroptosis	13/868	178/7206	0.047479098845