ko pathway ratio_in_study ratio_in_pop p_value ko05217 Basal cell carcinoma 23/374 68/7206 1.35023492791e-13 ko04390 Hippo signaling pathway 31/374 188/7206 6.85730945157e-09 ko04550 Signaling pathways regulating pluripotency of stem cells 28/374 165/7206 1.99110653851e-08 ko05224 Breast cancer 28/374 174/7206 6.52929169822e-08 ko04340 Hedgehog signaling pathway 15/374 58/7206 1.55001809638e-07 ko03030 DNA replication 12/374 38/7206 2.54329045885e-07 ko04080 Neuroactive ligand-receptor interaction 3/374 423/7206 3.81608788484e-07 ko04310 Wnt signaling pathway 26/374 181/7206 1.87122588632e-06 ko04330 Notch signaling pathway 14/374 62/7206 2.39802567883e-06 ko05200 Pathways in cancer 50/374 492/7206 4.00621576551e-06 ko05202 Transcriptional misregulation in cancer 25/374 188/7206 1.20062041114e-05 ko03410 Base excision repair 10/374 38/7206 1.60816621287e-05 ko04110 Cell cycle 21/374 145/7206 1.63800201663e-05 ko05205 Proteoglycans in cancer 31/374 271/7206 3.11097746304e-05 ko04950 Maturity onset diabetes of the young 8/374 29/7206 8.00542200682e-05 ko05010 Alzheimer's disease 1/374 202/7206 0.000521457828101 ko04612 Antigen processing and presentation 12/374 77/7206 0.000550012226573 ko04111 Cell cycle - yeast 13/374 90/7206 0.000692775269885 ko04360 Axon guidance 24/374 233/7206 0.00129350924339 ko04723 Retrograde endocannabinoid signaling 1/374 175/7206 0.00155454129099 ko05166 HTLV-I infection 28/374 292/7206 0.0016562629827 ko04921 Oxytocin signaling pathway 2/374 209/7206 0.00217618017472 ko04391 Hippo signaling pathway - fly 12/374 90/7206 0.00223312770275 ko04910 Insulin signaling pathway 1/374 172/7206 0.00241374760711 ko04350 TGF-beta signaling pathway 13/374 103/7206 0.00245230838164 ko03015 mRNA surveillance pathway 12/374 93/7206 0.00295342067508 ko04062 Chemokine signaling pathway 2/374 201/7206 0.0031034322454 ko04725 Cholinergic synapse 1/374 160/7206 0.00331813958174 ko03040 Spliceosome 16/374 145/7206 0.00374764704583 ko04144 Endocytosis 7/374 342/7206 0.0054833869485 ko05222 Small cell lung cancer 11/374 89/7206 0.00605444646548 ko03420 Nucleotide excision repair 7/374 46/7206 0.00889607724821 ko04931 Insulin resistance 1/374 137/7206 0.0101982254867 ko04726 Serotonergic synapse 1/374 137/7206 0.0101982254867 ko04020 Calcium signaling pathway 5/374 265/7206 0.0102790460201 ko05418 Fluid shear stress and atherosclerosis 17/374 173/7206 0.0132739127762 ko04072 Phospholipase D signaling pathway 3/374 197/7206 0.013549813166 ko00240 Pyrimidine metabolism 12/374 110/7206 0.0140472831169 ko05206 MicroRNAs in cancer 17/374 177/7206 0.0144598800696 ko04922 Glucagon signaling pathway 1/374 128/7206 0.0146851328265 ko03020 RNA polymerase 5/374 29/7206 0.0155338943016 ko05130 Pathogenic Escherichia coli infection 9/374 77/7206 0.0176203316337 ko00670 One carbon pool by folate 4/374 20/7206 0.0178511137917 ko00514 Other types of O-glycan biosynthesis 5/374 30/7206 0.017869551474 ko04022 cGMP-PKG signaling pathway 4/374 216/7206 0.0189131175584 ko04211 Longevity regulating pathway 1/374 123/7206 0.0216172804307 ko04066 HIF-1 signaling pathway 1/374 123/7206 0.0216172804307 ko03430 Mismatch repair 4/374 22/7206 0.024845217798 ko04113 Meiosis - yeast 8/374 70/7206 0.0276958124778 ko04070 Phosphatidylinositol signaling system 1/374 112/7206 0.0305996691572 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 4/374 26/7206 0.0431943525365 ko04925 Aldosterone synthesis and secretion 1/374 105/7206 0.0441394430497 ko04341 Hedgehog signaling pathway - fly 5/374 38/7206 0.0449983702635 ko04060 Cytokine-cytokine receptor interaction 4/374 191/7206 0.0469108814867 ko05231 Choline metabolism in cancer 2/374 134/7206 0.0481365085524