ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	98/716	423/7206	1.47453801377e-16
ko04724	Glutamatergic synapse	50/716	152/7206	3.68731632179e-15
ko05032	Morphine addiction	39/716	110/7206	2.84394609373e-13
ko05033	Nicotine addiction	25/716	56/7206	1.60018408914e-11
ko04713	Circadian entrainment	41/716	136/7206	2.8813849324e-11
ko04020	Calcium signaling pathway	62/716	265/7206	6.82910020603e-11
ko04024	cAMP signaling pathway	60/716	279/7206	4.39247396762e-09
ko04727	GABAergic synapse	32/716	110/7206	1.18259035628e-08
ko04921	Oxytocin signaling pathway	48/716	209/7206	2.19287159933e-08
ko04721	Synaptic vesicle cycle	26/716	80/7206	2.27992892016e-08
ko04728	Dopaminergic synapse	44/716	185/7206	2.47206788882e-08
ko04723	Retrograde endocannabinoid signaling	42/716	175/7206	4.34317962266e-08
ko04725	Cholinergic synapse	39/716	160/7206	1.12878655517e-07
ko04911	Insulin secretion	31/716	117/7206	2.12961623269e-07
ko04070	Phosphatidylinositol signaling system	27/716	112/7206	9.09260314297e-06
ko04261	Adrenergic signaling in cardiomyocytes	40/716	205/7206	2.45667621784e-05
ko04726	Serotonergic synapse	30/716	137/7206	3.09699457745e-05
ko03010	Ribosome	1/716	129/7206	3.69136342927e-05
ko04022	cGMP-PKG signaling pathway	41/716	216/7206	3.99355210556e-05
ko05322	Systemic lupus erythematosus	2/716	151/7206	4.30820264855e-05
ko04072	Phospholipase D signaling pathway	38/716	197/7206	5.12242531351e-05
ko05031	Amphetamine addiction	22/716	91/7206	5.80118028533e-05
ko03013	RNA transport	3/716	166/7206	5.85203475731e-05
ko03040	Spliceosome	2/716	145/7206	6.00071142346e-05
ko04720	Long-term potentiation	23/716	99/7206	0.000106507926139
ko04744	Phototransduction	12/716	36/7206	0.000111497455528
ko04970	Salivary secretion	22/716	95/7206	0.000160485971553
ko04742	Taste transduction	16/716	61/7206	0.000214045252961
ko04971	Gastric acid secretion	22/716	98/7206	0.000220196641629
ko04010	MAPK signaling pathway	51/716	321/7206	0.000561409284679
ko05203	Viral carcinogenesis	12/716	277/7206	0.000671612079218
ko04710	Circadian rhythm	12/716	43/7206	0.000711916926357
ko04925	Aldosterone synthesis and secretion	22/716	105/7206	0.000724182229992
ko04730	Long-term depression	17/716	78/7206	0.00166592089346
ko04110	Cell cycle	4/716	145/7206	0.00173198793065
ko04966	Collecting duct acid secretion	8/716	26/7206	0.00280829335722
ko04745	Phototransduction - fly	10/716	38/7206	0.00315447382056
ko00562	Inositol phosphate metabolism	18/716	89/7206	0.00342208784378
ko04972	Pancreatic secretion	21/716	111/7206	0.00344043910414
ko05030	Cocaine addiction	15/716	73/7206	0.00519689457736
ko04750	Inflammatory mediator regulation of TRP channels	22/716	122/7206	0.00534585816257
ko04014	Ras signaling pathway	42/716	279/7206	0.00561731886908
ko05164	Influenza A	7/716	167/7206	0.00850730278618
ko04930	Type II diabetes mellitus	12/716	54/7206	0.00919495836409
ko04922	Glucagon signaling pathway	22/716	128/7206	0.0102904394029
ko05169	Epstein-Barr virus infection	10/716	206/7206	0.0124009233282
ko02010	ABC transporters	9/716	39/7206	0.0124100888335
ko04360	Axon guidance	35/716	233/7206	0.013662227332
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/716	59/7206	0.0139052978506
ko05230	Central carbon metabolism in cancer	15/716	81/7206	0.0145805315849
ko00680	Methane metabolism	8/716	34/7206	0.0160350245863
ko04960	Aldosterone-regulated sodium reabsorption	9/716	41/7206	0.0171610708825
ko05231	Choline metabolism in cancer	22/716	134/7206	0.0183971376266
ko04964	Proximal tubule bicarbonate reclamation	7/716	29/7206	0.0207029515684
ko05168	Herpes simplex infection	9/716	182/7206	0.0228619273126
ko04071	Sphingolipid signaling pathway	25/716	162/7206	0.0233873837669
ko04015	Rap1 signaling pathway	39/716	278/7206	0.0242142518078
ko04514	Cell adhesion molecules (CAMs)	21/716	130/7206	0.0250207510694
ko05224	Breast cancer	9/716	174/7206	0.0291997961902
ko05110	Vibrio cholerae infection	12/716	63/7206	0.0303035279771
ko05130	Pathogenic Escherichia coli infection	2/716	77/7206	0.0321156912677
ko04612	Antigen processing and presentation	2/716	77/7206	0.0321156912677
ko04711	Circadian rhythm - fly	4/716	13/7206	0.0333206409281
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/716	79/7206	0.0342174152975
ko05202	Transcriptional misregulation in cancer	10/716	188/7206	0.0345516870363
ko05161	Hepatitis B	9/716	173/7206	0.0382586472526
ko00280	Valine, leucine and isoleucine degradation	1/716	54/7206	0.0395763124175
ko04260	Cardiac muscle contraction	16/716	98/7206	0.040533063145
ko04371	Apelin signaling pathway	26/716	177/7206	0.0407408280924
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/716	14/7206	0.0430834612861
ko04141	Protein processing in endoplasmic reticulum	10/716	184/7206	0.0444054010945
ko04657	IL-17 signaling pathway	3/716	87/7206	0.0448384788705
ko04666	Fc gamma R-mediated phagocytosis	19/716	122/7206	0.0456333896922
ko00010	Glycolysis / Gluconeogenesis	13/716	74/7206	0.0468296842766
ko05014	Amyotrophic lateral sclerosis (ALS)	13/716	74/7206	0.0468296842766