ko pathway ratio_in_study ratio_in_pop p_value ko04925 Aldosterone synthesis and secretion 17/424 105/7206 0.000118395999992 ko04060 Cytokine-cytokine receptor interaction 25/424 191/7206 0.000134372424763 ko04020 Calcium signaling pathway 30/424 265/7206 0.000461937541529 ko04710 Circadian rhythm 9/424 43/7206 0.00072919169467 ko04022 cGMP-PKG signaling pathway 25/424 216/7206 0.00103106977491 ko04724 Glutamatergic synapse 19/424 152/7206 0.00150205677883 ko04380 Osteoclast differentiation 17/424 134/7206 0.00238440477199 ko03040 Spliceosome 1/424 145/7206 0.00344303058994 ko04110 Cell cycle 1/424 145/7206 0.00344303058994 ko03013 RNA transport 2/424 166/7206 0.00423304497573 ko04745 Phototransduction - fly 7/424 38/7206 0.00598245984086 ko04070 Phosphatidylinositol signaling system 14/424 112/7206 0.00684635022448 ko03010 Ribosome 1/424 129/7206 0.00698561902412 ko04933 AGE-RAGE signaling pathway in diabetic complications 16/424 135/7206 0.00803603783842 ko04713 Circadian entrainment 16/424 136/7206 0.00831544209067 ko00140 Steroid hormone biosynthesis 7/424 41/7206 0.00915806303293 ko04725 Cholinergic synapse 18/424 160/7206 0.0093319866864 ko00051 Fructose and mannose metabolism 7/424 42/7206 0.0104492598739 ko00565 Ether lipid metabolism 7/424 42/7206 0.0104492598739 ko05167 Kaposi's sarcoma-associated herpesvirus infection 20/424 191/7206 0.0115102172438 ko05322 Systemic lupus erythematosus 2/424 151/7206 0.0126939573104 ko04658 Th1 and Th2 cell differentiation 12/424 96/7206 0.0130846197826 ko04921 Oxytocin signaling pathway 21/424 209/7206 0.0157544882331 ko04924 Renin secretion 11/424 86/7206 0.0168546573255 ko04750 Inflammatory mediator regulation of TRP channels 14/424 122/7206 0.0171087332468 ko04120 Ubiquitin mediated proteolysis 2/424 138/7206 0.0171666314449 ko04072 Phospholipase D signaling pathway 20/424 197/7206 0.0196088303049 ko04672 Intestinal immune network for IgA production 6/424 37/7206 0.0196863896582 ko05145 Toxoplasmosis 14/424 126/7206 0.0197833182868 ko05031 Amphetamine addiction 11/424 91/7206 0.0211350721408 ko00592 alpha-Linolenic acid metabolism 4/424 19/7206 0.0226225142815 ko04514 Cell adhesion molecules (CAMs) 14/424 130/7206 0.0234433535109 ko04610 Complement and coagulation cascades 10/424 79/7206 0.0249173600822 ko05230 Central carbon metabolism in cancer 10/424 81/7206 0.0269371286459 ko00120 Primary bile acid biosynthesis 4/424 20/7206 0.0270001043109 ko04650 Natural killer cell mediated cytotoxicity 11/424 97/7206 0.0292182241686 ko04014 Ras signaling pathway 25/424 279/7206 0.036423955454 ko04711 Circadian rhythm - fly 3/424 13/7206 0.0371982730219 ko04728 Dopaminergic synapse 18/424 185/7206 0.0372374918352 ko04071 Sphingolipid signaling pathway 16/424 162/7206 0.0403100012176 ko04080 Neuroactive ligand-receptor interaction 35/424 423/7206 0.0420248755373 ko05321 Inflammatory bowel disease (IBD) 7/424 56/7206 0.0446162872906 ko04360 Axon guidance 21/424 233/7206 0.0465974825816 ko04720 Long-term potentiation 11/424 99/7206 0.0475466199959 ko04261 Adrenergic signaling in cardiomyocytes 19/424 205/7206 0.0482691259698 ko05034 Alcoholism 7/424 238/7206 0.0491509332814 ko04512 ECM-receptor interaction 9/424 79/7206 0.0495224160295