ko pathway ratio_in_study ratio_in_pop p_value ko05224 Breast cancer 11/102 174/7206 3.14329033176e-05 ko04390 Hippo signaling pathway 11/102 188/7206 6.40377664949e-05 ko04916 Melanogenesis 9/102 142/7206 0.000168112762133 ko04514 Cell adhesion molecules (CAMs) 8/102 130/7206 0.000478698489597 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 6/102 79/7206 0.000836864333169 ko04330 Notch signaling pathway 5/102 62/7206 0.00175868529715 ko05217 Basal cell carcinoma 5/102 68/7206 0.00265003383739 ko05200 Pathways in cancer 15/102 492/7206 0.00437012107849 ko04370 VEGF signaling pathway 5/102 77/7206 0.00454498246342 ko04730 Long-term depression 5/102 78/7206 0.00480271062291 ko04670 Leukocyte transendothelial migration 7/102 151/7206 0.00541443735161 ko04011 MAPK signaling pathway - yeast 4/102 53/7206 0.00651435822203 ko04668 TNF signaling pathway 6/102 120/7206 0.00691085157429 ko04912 GnRH signaling pathway 6/102 122/7206 0.00747688658444 ko00512 Mucin type O-glycan biosynthesis 3/102 29/7206 0.00770315335608 ko04550 Signaling pathways regulating pluripotency of stem cells 7/102 165/7206 0.00868658873292 ko04658 Th1 and Th2 cell differentiation 5/102 96/7206 0.0113949134337 ko04726 Serotonergic synapse 6/102 137/7206 0.0128391388994 ko00564 Glycerophospholipid metabolism 5/102 99/7206 0.0128996459582 ko00540 Lipopolysaccharide biosynthesis 1/102 1/7206 0.0141548709409 ko05205 Proteoglycans in cancer 9/102 271/7206 0.0142443197905 ko04530 Tight junction 8/102 228/7206 0.0151846793958 ko04015 Rap1 signaling pathway 9/102 278/7206 0.0165802082232 ko04014 Ras signaling pathway 9/102 279/7206 0.016935641766 ko04360 Axon guidance 8/102 233/7206 0.0170993396696 ko04060 Cytokine-cytokine receptor interaction 7/102 191/7206 0.0183106869275 ko05160 Hepatitis C 6/102 153/7206 0.0210609257022 ko00565 Ether lipid metabolism 3/102 42/7206 0.0212079244376 ko04722 Neurotrophin signaling pathway 6/102 160/7206 0.0255817637416 ko00592 alpha-Linolenic acid metabolism 2/102 19/7206 0.0290096484864 ko04666 Fc gamma R-mediated phagocytosis 5/102 122/7206 0.0290406937798 ko01522 Endocrine resistance 5/102 124/7206 0.0308606482762 ko04918 Thyroid hormone synthesis 4/102 86/7206 0.0332230422045 ko00590 Arachidonic acid metabolism 3/102 52/7206 0.0369130367801 ko00591 Linoleic acid metabolism 2/102 22/7206 0.0381314399371 ko04371 Apelin signaling pathway 6/102 177/7206 0.0391437102441 ko04962 Vasopressin-regulated water reabsorption 3/102 58/7206 0.0485302709477