ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/196 191/7206 3.87384560813e-17 ko05340 Primary immunodeficiency 14/196 30/7206 7.57595651503e-15 ko04612 Antigen processing and presentation 17/196 77/7206 1.42947340963e-11 ko04650 Natural killer cell mediated cytotoxicity 18/196 97/7206 7.77098603235e-11 ko05168 Herpes simplex infection 24/196 182/7206 9.13879149616e-11 ko05320 Autoimmune thyroid disease 11/196 29/7206 1.02812921964e-10 ko05330 Allograft rejection 10/196 24/7206 2.48314174558e-10 ko05152 Tuberculosis 23/196 187/7206 9.52194890242e-10 ko04380 Osteoclast differentiation 19/196 134/7206 2.7346122874e-09 ko05164 Influenza A 21/196 167/7206 3.58621594021e-09 ko04621 NOD-like receptor signaling pathway 20/196 157/7206 6.8987632218e-09 ko05332 Graft-versus-host disease 8/196 18/7206 9.00444306392e-09 ko05140 Leishmaniasis 14/196 75/7206 9.95658192474e-09 ko04217 Necroptosis 21/196 178/7206 1.1466653618e-08 ko05162 Measles 17/196 120/7206 1.98112094064e-08 ko04659 Th17 cell differentiation 16/196 106/7206 2.08978601654e-08 ko04064 NF-kappa B signaling pathway 15/196 96/7206 3.64583390261e-08 ko05145 Toxoplasmosis 17/196 126/7206 4.17436941958e-08 ko04620 Toll-like receptor signaling pathway 15/196 100/7206 6.41615519441e-08 ko05321 Inflammatory bowel disease (IBD) 11/196 56/7206 2.32632467545e-07 ko04145 Phagosome 18/196 162/7206 3.38992293551e-07 ko04672 Intestinal immune network for IgA production 9/196 37/7206 4.36376387976e-07 ko04062 Chemokine signaling pathway 20/196 201/7206 4.49928597173e-07 ko04640 Hematopoietic cell lineage 11/196 64/7206 9.60431659126e-07 ko04940 Type I diabetes mellitus 8/196 32/7206 1.5594076493e-06 ko05310 Asthma 6/196 17/7206 3.61584174717e-06 ko04660 T cell receptor signaling pathway 14/196 124/7206 5.98473698456e-06 ko04658 Th1 and Th2 cell differentiation 12/196 96/7206 9.87781841583e-06 ko03050 Proteasome 9/196 54/7206 1.25005075607e-05 ko05150 Staphylococcus aureus infection 7/196 36/7206 4.22782596737e-05 ko04630 Jak-STAT signaling pathway 13/196 132/7206 5.63345439319e-05 ko05416 Viral myocarditis 8/196 55/7206 0.000105560891151 ko05144 Malaria 7/196 45/7206 0.000186819541521 ko04514 Cell adhesion molecules (CAMs) 12/196 130/7206 0.000202997313943 ko05167 Kaposi's sarcoma-associated herpesvirus infection 15/196 191/7206 0.000205178010562 ko05161 Hepatitis B 14/196 173/7206 0.000245368160855 ko05133 Pertussis 9/196 87/7206 0.000556210232702 ko05323 Rheumatoid arthritis 9/196 89/7206 0.000657812107463 ko04664 Fc epsilon RI signaling pathway 8/196 77/7206 0.00109507635076 ko04622 RIG-I-like receptor signaling pathway 7/196 62/7206 0.00137119490832 ko05142 Chagas disease (American trypanosomiasis) 10/196 130/7206 0.00276307524921 ko04210 Apoptosis 12/196 180/7206 0.00357783381695 ko04611 Platelet activation 11/196 163/7206 0.0047568793321 ko04666 Fc gamma R-mediated phagocytosis 9/196 122/7206 0.00585685900125 ko04670 Leukocyte transendothelial migration 10/196 151/7206 0.00795479750818 ko05166 HTLV-I infection 16/196 292/7206 0.00838110011812 ko05160 Hepatitis C 10/196 153/7206 0.00869571881756 ko04662 B cell receptor signaling pathway 7/196 88/7206 0.00979926865321 ko04510 Focal adhesion 1/196 240/7206 0.0230996664338 ko05131 Shigellosis 6/196 82/7206 0.0237676466769 ko05169 Epstein-Barr virus infection 11/196 206/7206 0.0277334414171 ko05016 Huntington's disease 1/196 215/7206 0.0315756507094 ko04080 Neuroactive ligand-receptor interaction 5/196 423/7206 0.0440527799049 ko04668 TNF signaling pathway 7/196 120/7206 0.0447624676503