ko pathway ratio_in_study ratio_in_pop p_value ko04390 Hippo signaling pathway 33/265 188/7206 2.74827879167e-14 ko05205 Proteoglycans in cancer 33/265 271/7206 8.34346626561e-10 ko05217 Basal cell carcinoma 16/265 68/7206 1.88005211127e-09 ko05200 Pathways in cancer 46/265 492/7206 2.35290210846e-09 ko04510 Focal adhesion 30/265 240/7206 2.79270609265e-09 ko05224 Breast cancer 25/265 174/7206 3.62847444532e-09 ko04550 Signaling pathways regulating pluripotency of stem cells 21/265 165/7206 5.60889338868e-07 ko04916 Melanogenesis 17/265 142/7206 1.58673610477e-05 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/265 79/7206 2.70968225395e-05 ko04530 Tight junction 22/265 228/7206 2.99891049872e-05 ko01522 Endocrine resistance 15/265 124/7206 4.46233498937e-05 ko04392 Hippo signaling pathway -multiple species 7/265 31/7206 0.000103474996292 ko04310 Wnt signaling pathway 18/265 181/7206 0.000109357112777 ko04670 Leukocyte transendothelial migration 16/265 151/7206 0.000125687679532 ko04512 ECM-receptor interaction 11/265 79/7206 0.000132437910441 ko04810 Regulation of actin cytoskeleton 23/265 264/7206 0.000140103112276 ko05100 Bacterial invasion of epithelial cells 12/265 99/7206 0.00025425116164 ko05206 MicroRNAs in cancer 17/265 177/7206 0.000258624121046 ko04514 Cell adhesion molecules (CAMs) 13/265 130/7206 0.000937143478355 ko05146 Amoebiasis 11/265 99/7206 0.000964615872263 ko04360 Axon guidance 19/265 233/7206 0.0010436317863 ko04668 TNF signaling pathway 12/265 120/7206 0.00146256894174 ko05222 Small cell lung cancer 10/265 89/7206 0.00149612348392 ko04391 Hippo signaling pathway - fly 10/265 90/7206 0.0016298440475 ko04330 Notch signaling pathway 8/265 62/7206 0.00181629658942 ko04658 Th1 and Th2 cell differentiation 10/265 96/7206 0.00265005387956 ko00590 Arachidonic acid metabolism 7/265 52/7206 0.00272447920414 ko04080 Neuroactive ligand-receptor interaction 5/265 423/7206 0.00298898670655 ko04011 MAPK signaling pathway - yeast 7/265 53/7206 0.00304270549707 ko05166 HTLV-I infection 21/265 292/7206 0.00353399091167 ko00512 Mucin type O-glycan biosynthesis 5/265 29/7206 0.00372499440042 ko04015 Rap1 signaling pathway 20/265 278/7206 0.00479768760906 ko04151 PI3K-Akt signaling pathway 25/265 390/7206 0.007767516983 ko05219 Bladder cancer 6/265 48/7206 0.00783897344833 ko04722 Neurotrophin signaling pathway 13/265 160/7206 0.00823293113019 ko04150 mTOR signaling pathway 14/265 184/7206 0.0086365324535 ko04611 Platelet activation 13/265 163/7206 0.00896004979782 ko05131 Shigellosis 8/265 82/7206 0.0102012092661 ko04350 TGF-beta signaling pathway 9/265 103/7206 0.0132127136861 ko05160 Hepatitis C 12/265 153/7206 0.0135516796054 ko04912 GnRH signaling pathway 10/265 122/7206 0.0141025714204 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/265 135/7206 0.0167787682622 ko04340 Hedgehog signaling pathway 6/265 58/7206 0.0190855292711 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/265 92/7206 0.0194934430069 ko04370 VEGF signaling pathway 7/265 77/7206 0.0225885836919 ko04974 Protein digestion and absorption 8/265 96/7206 0.0245199692301 ko04140 Autophagy - animal 1/265 164/7206 0.0322809135373 ko05212 Pancreatic cancer 7/265 83/7206 0.0324507280355 ko04014 Ras signaling pathway 17/265 279/7206 0.0347137716238 ko00540 Lipopolysaccharide biosynthesis 1/265 1/7206 0.0367749097974 ko04013 MAPK signaling pathway - fly 9/265 115/7206 0.0383577769088 ko04210 Apoptosis 12/265 180/7206 0.0419062740612 ko04666 Fc gamma R-mediated phagocytosis 9/265 122/7206 0.0452835727986 ko05012 Parkinson's disease 1/265 155/7206 0.0471982139304 ko00230 Purine metabolism 2/265 194/7206 0.0498667033944