ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	22/368	56/7206	8.898368401e-15
ko04727	GABAergic synapse	30/368	110/7206	1.09525180404e-14
ko04728	Dopaminergic synapse	39/368	185/7206	1.16375063552e-14
ko04724	Glutamatergic synapse	34/368	152/7206	1.04532266144e-13
ko04721	Synaptic vesicle cycle	24/368	80/7206	5.5353889343e-13
ko04723	Retrograde endocannabinoid signaling	34/368	175/7206	7.53247752354e-12
ko05032	Morphine addiction	25/368	110/7206	1.51554761486e-10
ko04911	Insulin secretion	23/368	117/7206	1.66225646754e-08
ko04726	Serotonergic synapse	25/368	137/7206	1.90615919808e-08
ko04725	Cholinergic synapse	27/368	160/7206	2.8927395291e-08
ko04360	Axon guidance	33/368	233/7206	6.99926677375e-08
ko04713	Circadian entrainment	24/368	136/7206	7.23282348886e-08
ko04024	cAMP signaling pathway	34/368	279/7206	1.9866150188e-06
ko04261	Adrenergic signaling in cardiomyocytes	27/368	205/7206	4.74164500188e-06
ko04010	MAPK signaling pathway	35/368	321/7206	2.05976523472e-05
ko04080	Neuroactive ligand-receptor interaction	42/368	423/7206	3.01005497735e-05
ko05031	Amphetamine addiction	15/368	91/7206	4.92429939983e-05
ko04964	Proximal tubule bicarbonate reclamation	8/368	29/7206	7.13915400283e-05
ko04514	Cell adhesion molecules (CAMs)	18/368	130/7206	9.73461494957e-05
ko04720	Long-term potentiation	14/368	99/7206	0.00046134453957
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/368	14/7206	0.000461358212477
ko04060	Cytokine-cytokine receptor interaction	1/368	191/7206	0.000724621443759
ko04071	Sphingolipid signaling pathway	19/368	162/7206	0.000748693606828
ko04921	Oxytocin signaling pathway	22/368	209/7206	0.00113325662739
ko05014	Amyotrophic lateral sclerosis (ALS)	11/368	74/7206	0.00121734127547
ko04971	Gastric acid secretion	13/368	98/7206	0.0013443425564
ko04730	Long-term depression	11/368	78/7206	0.00188733551868
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/368	59/7206	0.00278500863225
ko04742	Taste transduction	9/368	61/7206	0.00351372593805
ko05030	Cocaine addiction	10/368	73/7206	0.00372470666168
ko04972	Pancreatic secretion	13/368	111/7206	0.0041303456707
ko05016	Huntington's disease	3/368	215/7206	0.00696694985852
ko04072	Phospholipase D signaling pathway	19/368	197/7206	0.00751118404517
ko04970	Salivary secretion	11/368	95/7206	0.00874933777562
ko04744	Phototransduction	6/368	36/7206	0.00902178321482
ko04120	Ubiquitin mediated proteolysis	1/368	138/7206	0.0101599020466
ko05210	Colorectal cancer	10/368	86/7206	0.0118219150984
ko05110	Vibrio cholerae infection	8/368	63/7206	0.0141880809465
ko04540	Gap junction	13/368	128/7206	0.0145171345462
ko04260	Cardiac muscle contraction	11/368	98/7206	0.0166299798893
ko04960	Aldosterone-regulated sodium reabsorption	6/368	41/7206	0.0168249562245
ko05203	Viral carcinogenesis	6/368	277/7206	0.017775851715
ko04973	Carbohydrate digestion and absorption	6/368	42/7206	0.0188119940243
ko04930	Type II diabetes mellitus	7/368	54/7206	0.0190982223689
ko04940	Type I diabetes mellitus	5/368	32/7206	0.0218050466667
ko01200	Carbon metabolism	1/368	128/7206	0.0225643066452
ko04144	Endocytosis	27/368	342/7206	0.0226477814514
ko04015	Rap1 signaling pathway	23/368	278/7206	0.0246822990743
ko04114	Oocyte meiosis	13/368	139/7206	0.0304174102443
ko03040	Spliceosome	2/368	145/7206	0.0345392912355
ko02024	Quorum sensing	3/368	15/7206	0.038029987859
ko04966	Collecting duct acid secretion	4/368	26/7206	0.0410754669656
ko05142	Chagas disease (American trypanosomiasis)	12/368	130/7206	0.0416546973769
ko04745	Phototransduction - fly	5/368	38/7206	0.042441818739
ko04915	Estrogen signaling pathway	12/368	131/7206	0.0430162201409
ko04662	B cell receptor signaling pathway	9/368	88/7206	0.0445164693035
ko04145	Phagosome	14/368	162/7206	0.0461551449961
ko03013	RNA transport	3/368	166/7206	0.0485934704066
ko05164	Influenza A	3/368	167/7206	0.0487231246888