ko pathway ratio_in_study ratio_in_pop p_value ko04360 Axon guidance 49/380 233/7206 1.4303133747e-17 ko05033 Nicotine addiction 19/380 56/7206 2.36430249599e-11 ko04721 Synaptic vesicle cycle 18/380 80/7206 1.15963214927e-07 ko04391 Hippo signaling pathway - fly 16/380 90/7206 1.54329060707e-05 ko04728 Dopaminergic synapse 24/380 185/7206 3.53838146404e-05 ko04727 GABAergic synapse 17/380 110/7206 5.54559456882e-05 ko05217 Basal cell carcinoma 12/380 68/7206 0.00019299414332 ko05202 Transcriptional misregulation in cancer 22/380 188/7206 0.000373641325932 ko04514 Cell adhesion molecules (CAMs) 17/380 130/7206 0.00044406687795 ko04340 Hedgehog signaling pathway 10/380 58/7206 0.000793081481108 ko04141 Protein processing in endoplasmic reticulum 1/380 184/7206 0.00112074556116 ko04550 Signaling pathways regulating pluripotency of stem cells 19/380 165/7206 0.00115887778926 ko05030 Cocaine addiction 11/380 73/7206 0.00140790123413 ko05203 Viral carcinogenesis 4/380 277/7206 0.00143175137706 ko05032 Morphine addiction 14/380 110/7206 0.00181531404052 ko04140 Autophagy - animal 1/380 164/7206 0.00225782516758 ko04724 Glutamatergic synapse 17/380 152/7206 0.00282321224779 ko04723 Retrograde endocannabinoid signaling 19/380 175/7206 0.00283518691475 ko04621 NOD-like receptor signaling pathway 1/380 157/7206 0.00330084786224 ko04950 Maturity onset diabetes of the young 6/380 29/7206 0.00348873117374 ko04024 cAMP signaling pathway 26/380 279/7206 0.00390909240437 ko04974 Protein digestion and absorption 12/380 96/7206 0.00437720210941 ko04725 Cholinergic synapse 17/380 160/7206 0.0059815808917 ko00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 5/380 26/7206 0.0104291096488 ko04611 Platelet activation 2/380 163/7206 0.0123193798885 ko03013 RNA transport 2/380 166/7206 0.0125104827501 ko04060 Cytokine-cytokine receptor interaction 3/380 191/7206 0.0134518519343 ko05014 Amyotrophic lateral sclerosis (ALS) 9/380 74/7206 0.0152086627181 ko04270 Vascular smooth muscle contraction 2/380 154/7206 0.0173946061698 ko05016 Huntington's disease 4/380 215/7206 0.0190117801998 ko04211 Longevity regulating pathway 1/380 123/7206 0.0221282019167 ko04020 Calcium signaling pathway 6/380 265/7206 0.0238493574313 ko05322 Systemic lupus erythematosus 2/380 151/7206 0.0249768840288 ko05169 Epstein-Barr virus infection 4/380 206/7206 0.0257482461024 ko04218 Cellular senescence 3/380 177/7206 0.0257668284571 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/380 182/7206 0.0266957787728 ko04390 Hippo signaling pathway 17/380 188/7206 0.0293789568504 ko00240 Pyrimidine metabolism 1/380 110/7206 0.0305394700648 ko04911 Insulin secretion 12/380 117/7206 0.0327784175744 ko00604 Glycosphingolipid biosynthesis - ganglio series 3/380 14/7206 0.0343108662896 ko04961 Endocrine and other factor-regulated calcium reabsorption 7/380 59/7206 0.0344752781096 ko05164 Influenza A 3/380 167/7206 0.0353726123254 ko03040 Spliceosome 2/380 145/7206 0.0357118978592 ko04512 ECM-receptor interaction 9/380 79/7206 0.0360397100189 ko04080 Neuroactive ligand-receptor interaction 32/380 423/7206 0.0424209435364 ko04914 Progesterone-mediated oocyte maturation 1/380 104/7206 0.0442026325293 ko05210 Colorectal cancer 9/380 86/7206 0.0457814596639 ko04630 Jak-STAT signaling pathway 2/380 132/7206 0.0480834927136