ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	185/1132	423/7206	5.42016559699e-46
ko04724	Glutamatergic synapse	83/1132	152/7206	5.06279461071e-29
ko05033	Nicotine addiction	44/1132	56/7206	1.6936845481e-25
ko04713	Circadian entrainment	70/1132	136/7206	1.30455526962e-22
ko05032	Morphine addiction	61/1132	110/7206	4.66722131709e-22
ko04728	Dopaminergic synapse	80/1132	185/7206	1.37271762828e-19
ko04725	Cholinergic synapse	72/1132	160/7206	6.43613481287e-19
ko04727	GABAergic synapse	57/1132	110/7206	8.46492329279e-19
ko04721	Synaptic vesicle cycle	47/1132	80/7206	1.15581106795e-18
ko04020	Calcium signaling pathway	98/1132	265/7206	6.2858599797e-18
ko04723	Retrograde endocannabinoid signaling	72/1132	175/7206	2.60621710236e-16
ko04726	Serotonergic synapse	59/1132	137/7206	1.21086862301e-14
ko04911	Insulin secretion	53/1132	117/7206	2.2019027136e-14
ko04024	cAMP signaling pathway	94/1132	279/7206	2.97095426523e-14
ko04742	Taste transduction	34/1132	61/7206	6.25884221766e-13
ko04921	Oxytocin signaling pathway	73/1132	209/7206	5.28425937176e-12
ko04744	Phototransduction	23/1132	36/7206	7.76036910615e-11
ko05031	Amphetamine addiction	39/1132	91/7206	4.8481460958e-10
ko04720	Long-term potentiation	41/1132	99/7206	6.19308934286e-10
ko04740	Olfactory transduction	35/1132	80/7206	1.94075634651e-09
ko04970	Salivary secretion	39/1132	95/7206	2.20751758997e-09
ko03010	Ribosome	1/1132	129/7206	1.09776645924e-08
ko04925	Aldosterone synthesis and secretion	40/1132	105/7206	1.78380376879e-08
ko03040	Spliceosome	3/1132	145/7206	9.45905158386e-08
ko04261	Adrenergic signaling in cardiomyocytes	61/1132	205/7206	2.5871216214e-07
ko04971	Gastric acid secretion	36/1132	98/7206	3.15310011705e-07
ko05322	Systemic lupus erythematosus	4/1132	151/7206	3.31475986894e-07
ko04730	Long-term depression	30/1132	78/7206	8.5536068477e-07
ko03013	RNA transport	6/1132	166/7206	1.23357802881e-06
ko05030	Cocaine addiction	28/1132	73/7206	2.10925466487e-06
ko05168	Herpes simplex infection	8/1132	182/7206	2.33412113946e-06
ko04120	Ubiquitin mediated proteolysis	4/1132	138/7206	2.33782081073e-06
ko05164	Influenza A	7/1132	167/7206	4.21247969281e-06
ko04972	Pancreatic secretion	36/1132	111/7206	9.09367356153e-06
ko04022	cGMP-PKG signaling pathway	59/1132	216/7206	9.83185010841e-06
ko04745	Phototransduction - fly	17/1132	38/7206	2.05202093958e-05
ko03008	Ribosome biogenesis in eukaryotes	1/1132	79/7206	3.26163540796e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	26/1132	74/7206	3.3239909367e-05
ko04514	Cell adhesion molecules (CAMs)	39/1132	130/7206	4.21947699205e-05
ko04750	Inflammatory mediator regulation of TRP channels	37/1132	122/7206	4.22477105085e-05
ko04966	Collecting duct acid secretion	13/1132	26/7206	4.62869486628e-05
ko04540	Gap junction	38/1132	128/7206	6.38438564492e-05
ko04110	Cell cycle	7/1132	145/7206	6.97796925209e-05
ko04060	Cytokine-cytokine receptor interaction	12/1132	191/7206	0.000107709477786
ko04360	Axon guidance	59/1132	233/7206	0.000109034378663
ko05162	Measles	5/1132	120/7206	0.000114510264249
ko05203	Viral carcinogenesis	22/1132	277/7206	0.000136279433797
ko04010	MAPK signaling pathway	76/1132	321/7206	0.000150446254616
ko04070	Phosphatidylinositol signaling system	33/1132	112/7206	0.000198328371552
ko04621	NOD-like receptor signaling pathway	9/1132	157/7206	0.000209893906824
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/1132	182/7206	0.00061877254936
ko04141	Protein processing in endoplasmic reticulum	13/1132	184/7206	0.00063046632657
ko04014	Ras signaling pathway	65/1132	279/7206	0.000739527823507
ko05169	Epstein-Barr virus infection	16/1132	206/7206	0.000882528125026
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/1132	79/7206	0.000899602274851
ko04630	Jak-STAT signaling pathway	8/1132	132/7206	0.00101457573369
ko04976	Bile secretion	24/1132	80/7206	0.00104081297697
ko05110	Vibrio cholerae infection	20/1132	63/7206	0.00134955916669
ko00520	Amino sugar and nucleotide sugar metabolism	1/1132	55/7206	0.00134974383707
ko04146	Peroxisome	4/1132	89/7206	0.00177835706715
ko04915	Estrogen signaling pathway	34/1132	131/7206	0.00224370549882
ko05140	Leishmaniasis	3/1132	75/7206	0.0022486737255
ko04612	Antigen processing and presentation	3/1132	77/7206	0.00231405606629
ko04064	NF-kappa B signaling pathway	5/1132	96/7206	0.00266531599223
ko04072	Phospholipase D signaling pathway	47/1132	197/7206	0.00271063118587
ko04964	Proximal tubule bicarbonate reclamation	11/1132	29/7206	0.00307133287252
ko04916	Melanogenesis	36/1132	142/7206	0.0032836796643
ko04626	Plant-pathogen interaction	8/1132	18/7206	0.00361931702665
ko04924	Renin secretion	24/1132	86/7206	0.00401970564432
ko05161	Hepatitis B	14/1132	173/7206	0.00406638055997
ko04371	Apelin signaling pathway	42/1132	177/7206	0.00457079520913
ko04260	Cardiac muscle contraction	26/1132	98/7206	0.00496884939952
ko05414	Dilated cardiomyopathy	29/1132	112/7206	0.00546894406061
ko05205	Proteoglycans in cancer	27/1132	271/7206	0.00640699486448
ko05144	Malaria	1/1132	45/7206	0.00682160210132
ko00071	Fatty acid degradation	1/1132	45/7206	0.00682160210132
ko03420	Nucleotide excision repair	1/1132	46/7206	0.00693927100699
ko04930	Type II diabetes mellitus	16/1132	54/7206	0.00812717860555
ko05166	HTLV-I infection	30/1132	292/7206	0.00840777929267
ko04960	Aldosterone-regulated sodium reabsorption	13/1132	41/7206	0.00880656656419
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1132	59/7206	0.010484538446
ko03022	Basal transcription factors	1/1132	44/7206	0.01065447063
ko00280	Valine, leucine and isoleucine degradation	2/1132	54/7206	0.012908272042
ko05145	Toxoplasmosis	10/1132	126/7206	0.0131157150548
ko04270	Vascular smooth muscle contraction	36/1132	154/7206	0.0131798819941
ko04622	RIG-I-like receptor signaling pathway	3/1132	62/7206	0.0134836788649
ko04214	Apoptosis - fly	4/1132	72/7206	0.0138307592483
ko04710	Circadian rhythm	13/1132	43/7206	0.0178552699637
ko04922	Glucagon signaling pathway	30/1132	128/7206	0.0195399114321
ko05016	Huntington's disease	22/1132	215/7206	0.0224348423145
ko04672	Intestinal immune network for IgA production	1/1132	37/7206	0.0226809469697
ko04658	Th1 and Th2 cell differentiation	7/1132	96/7206	0.022738243324
ko03410	Base excision repair	1/1132	38/7206	0.0229889984871
ko04657	IL-17 signaling pathway	6/1132	87/7206	0.024749266184
ko05133	Pertussis	6/1132	87/7206	0.024749266184
ko00260	Glycine, serine and threonine metabolism	2/1132	48/7206	0.0263829988484
ko05321	Inflammatory bowel disease (IBD)	3/1132	56/7206	0.0270218892262
ko04912	GnRH signaling pathway	28/1132	122/7206	0.0324053287752
ko05131	Shigellosis	6/1132	82/7206	0.0324675844794
ko00640	Propanoate metabolism	1/1132	34/7206	0.0337799272544
ko00500	Starch and sucrose metabolism	1/1132	35/7206	0.0338972117474
ko00310	Lysine degradation	5/1132	73/7206	0.0348819023908
ko04620	Toll-like receptor signaling pathway	8/1132	100/7206	0.0365595626827
ko04217	Necroptosis	18/1132	178/7206	0.0368103721918
ko05416	Viral myocarditis	3/1132	55/7206	0.0385120624619
ko05222	Small cell lung cancer	7/1132	89/7206	0.0397033748387
ko04711	Circadian rhythm - fly	5/1132	13/7206	0.0407035539839
ko04015	Rap1 signaling pathway	56/1132	278/7206	0.0433806588609
ko04610	Complement and coagulation cascades	6/1132	79/7206	0.0435231651006
ko04114	Oocyte meiosis	31/1132	139/7206	0.0442976895907