ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	157/840	423/7206	1.9042517859e-45
ko05033	Nicotine addiction	45/840	56/7206	1.44022861532e-32
ko04724	Glutamatergic synapse	76/840	152/7206	3.74329234992e-32
ko05032	Morphine addiction	59/840	110/7206	2.94855033058e-27
ko04727	GABAergic synapse	57/840	110/7206	2.40593859233e-25
ko04713	Circadian entrainment	62/840	136/7206	1.34292528331e-23
ko04728	Dopaminergic synapse	70/840	185/7206	8.66174059938e-21
ko04024	cAMP signaling pathway	88/840	279/7206	1.04016181207e-19
ko04723	Retrograde endocannabinoid signaling	66/840	175/7206	1.45232125805e-19
ko04911	Insulin secretion	50/840	117/7206	9.28599119766e-18
ko04721	Synaptic vesicle cycle	39/840	80/7206	1.64624908576e-16
ko04725	Cholinergic synapse	58/840	160/7206	2.18663261315e-16
ko04020	Calcium signaling pathway	77/840	265/7206	6.9130994615e-15
ko04726	Serotonergic synapse	48/840	137/7206	4.0538160054e-13
ko04742	Taste transduction	29/840	61/7206	2.98368624743e-12
ko04261	Adrenergic signaling in cardiomyocytes	60/840	205/7206	3.69393475275e-12
ko05031	Amphetamine addiction	36/840	91/7206	6.298866795e-12
ko04921	Oxytocin signaling pathway	60/840	209/7206	1.28716401459e-11
ko04720	Long-term potentiation	36/840	99/7206	1.10336857671e-10
ko04925	Aldosterone synthesis and secretion	34/840	105/7206	1.1782650423e-08
ko05030	Cocaine addiction	27/840	73/7206	1.58720646623e-08
ko04970	Salivary secretion	30/840	95/7206	1.61041495179e-07
ko04010	MAPK signaling pathway	69/840	321/7206	2.64314941876e-07
ko03040	Spliceosome	1/840	145/7206	5.5835101564e-07
ko04971	Gastric acid secretion	29/840	98/7206	1.18943391365e-06
ko04072	Phospholipase D signaling pathway	47/840	197/7206	1.28899804618e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/840	74/7206	1.63250990095e-06
ko04972	Pancreatic secretion	31/840	111/7206	2.98355930898e-06
ko04022	cGMP-PKG signaling pathway	47/840	216/7206	1.96858915316e-05
ko05203	Viral carcinogenesis	12/840	277/7206	2.23099213658e-05
ko04360	Axon guidance	49/840	233/7206	2.75143256597e-05
ko04260	Cardiac muscle contraction	26/840	98/7206	4.10468457227e-05
ko05322	Systemic lupus erythematosus	4/840	151/7206	9.30181216276e-05
ko04744	Phototransduction	13/840	36/7206	0.000118316685368
ko04621	NOD-like receptor signaling pathway	5/840	157/7206	0.00021945409338
ko04730	Long-term depression	21/840	78/7206	0.00021946047806
ko04745	Phototransduction - fly	13/840	38/7206	0.000221958589412
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/840	79/7206	0.000246820258216
ko04514	Cell adhesion molecules (CAMs)	30/840	130/7206	0.00024779628154
ko05168	Herpes simplex infection	7/840	182/7206	0.000257132188157
ko04915	Estrogen signaling pathway	30/840	131/7206	0.00026366137487
ko05164	Influenza A	6/840	167/7206	0.000339171184546
ko04120	Ubiquitin mediated proteolysis	4/840	138/7206	0.000395530046866
ko04750	Inflammatory mediator regulation of TRP channels	28/840	122/7206	0.000490616623133
ko04070	Phosphatidylinositol signaling system	26/840	112/7206	0.000492414521093
ko04060	Cytokine-cytokine receptor interaction	8/840	191/7206	0.000518299641746
ko04110	Cell cycle	5/840	145/7206	0.0006119243509
ko04141	Protein processing in endoplasmic reticulum	8/840	184/7206	0.000687022585709
ko04740	Olfactory transduction	20/840	80/7206	0.000699686732274
ko04540	Gap junction	28/840	128/7206	0.000764521223571
ko03013	RNA transport	7/840	166/7206	0.0012942099786
ko00240	Pyrimidine metabolism	3/840	110/7206	0.00138492200763
ko05414	Dilated cardiomyopathy	25/840	112/7206	0.00148340998686
ko04966	Collecting duct acid secretion	9/840	26/7206	0.00188529105259
ko05110	Vibrio cholerae infection	16/840	63/7206	0.00223800294677
ko04976	Bile secretion	19/840	80/7206	0.00225129279303
ko04930	Type II diabetes mellitus	14/840	54/7206	0.00404495859136
ko04964	Proximal tubule bicarbonate reclamation	9/840	29/7206	0.00438186733972
ko04064	NF-kappa B signaling pathway	3/840	96/7206	0.00570538861943
ko05169	Epstein-Barr virus infection	12/840	206/7206	0.00571691858246
ko04924	Renin secretion	19/840	86/7206	0.00580363602664
ko05162	Measles	5/840	120/7206	0.0061297017571
ko05205	Proteoglycans in cancer	18/840	271/7206	0.00674277617439
ko04612	Antigen processing and presentation	2/840	77/7206	0.00699851884001
ko04610	Complement and coagulation cascades	2/840	79/7206	0.00713706393712
ko03008	Ribosome biogenesis in eukaryotes	2/840	79/7206	0.00713706393712
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/840	59/7206	0.00734234282894
ko00330	Arginine and proline metabolism	1/840	61/7206	0.00814280081909
ko04722	Neurotrophin signaling pathway	30/840	160/7206	0.00829126145336
ko04014	Ras signaling pathway	47/840	279/7206	0.00981688976388
ko05140	Leishmaniasis	2/840	75/7206	0.0101671843139
ko04146	Peroxisome	3/840	89/7206	0.011400887816
ko05161	Hepatitis B	10/840	173/7206	0.0115287728566
ko04371	Apelin signaling pathway	32/840	177/7206	0.0120609011592
ko04711	Circadian rhythm - fly	5/840	13/7206	0.0122700378821
ko04626	Plant-pathogen interaction	6/840	18/7206	0.0132968428105
ko04710	Circadian rhythm	11/840	43/7206	0.0134232338653
ko00680	Methane metabolism	9/840	34/7206	0.0134793017501
ko05231	Choline metabolism in cancer	25/840	134/7206	0.0143634834756
ko00310	Lysine degradation	2/840	73/7206	0.0151769282849
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/840	14/7206	0.0172892315361
ko00562	Inositol phosphate metabolism	18/840	89/7206	0.0184093778113
ko04510	Focal adhesion	17/840	240/7206	0.0239359212439
ko04973	Carbohydrate digestion and absorption	10/840	42/7206	0.0253380890143
ko04918	Thyroid hormone synthesis	17/840	86/7206	0.0264274453916
ko00590	Arachidonic acid metabolism	1/840	52/7206	0.0267925372812
ko05410	Hypertrophic cardiomyopathy (HCM)	19/840	100/7206	0.0273826444898
ko04350	TGF-beta signaling pathway	5/840	103/7206	0.0291035556769
ko05016	Huntington's disease	15/840	215/7206	0.0302888376944
ko04912	GnRH signaling pathway	22/840	122/7206	0.0324674491777
ko04015	Rap1 signaling pathway	44/840	278/7206	0.0353244273131
ko03420	Nucleotide excision repair	1/840	46/7206	0.037844443596
ko05204	Chemical carcinogenesis	1/840	48/7206	0.0386934395136
ko00260	Glycine, serine and threonine metabolism	1/840	48/7206	0.0386934395136
ko05034	Alcoholism	38/840	238/7206	0.0397371232215
ko04630	Jak-STAT signaling pathway	8/840	132/7206	0.0400444225845
ko01212	Fatty acid metabolism	2/840	60/7206	0.0418384053751
ko04217	Necroptosis	12/840	178/7206	0.0432456478731
ko04330	Notch signaling pathway	2/840	62/7206	0.0433617417152
ko04923	Regulation of lipolysis in adipocytes	15/840	77/7206	0.0465551232191
ko04140	Autophagy - animal	11/840	164/7206	0.0480493713969
ko04960	Aldosterone-regulated sodium reabsorption	9/840	41/7206	0.0492121278452