ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	163/1124	423/7206	2.21893818463e-32
ko04724	Glutamatergic synapse	72/1124	152/7206	1.09143235229e-20
ko04020	Calcium signaling pathway	95/1124	265/7206	1.45754857778e-16
ko05033	Nicotine addiction	36/1124	56/7206	1.77922763536e-16
ko05032	Morphine addiction	52/1124	110/7206	3.22708534503e-15
ko04713	Circadian entrainment	59/1124	136/7206	5.81967523745e-15
ko04727	GABAergic synapse	50/1124	110/7206	7.75346853135e-14
ko04725	Cholinergic synapse	63/1124	160/7206	1.64528355185e-13
ko04726	Serotonergic synapse	55/1124	137/7206	2.35746111833e-12
ko04728	Dopaminergic synapse	66/1124	185/7206	9.64223177233e-12
ko04723	Retrograde endocannabinoid signaling	63/1124	175/7206	2.04518305524e-11
ko04921	Oxytocin signaling pathway	71/1124	209/7206	2.33390717138e-11
ko04024	cAMP signaling pathway	87/1124	279/7206	3.25031647199e-11
ko04721	Synaptic vesicle cycle	37/1124	80/7206	7.50869536278e-11
ko04911	Insulin secretion	47/1124	117/7206	9.35238940319e-11
ko03040	Spliceosome	2/1124	145/7206	1.03005106303e-08
ko03010	Ribosome	1/1124	129/7206	1.08003593489e-08
ko03013	RNA transport	4/1124	166/7206	2.98790504208e-08
ko05322	Systemic lupus erythematosus	4/1124	151/7206	3.21454678439e-07
ko04970	Salivary secretion	35/1124	95/7206	3.93146490046e-07
ko04070	Phosphatidylinositol signaling system	39/1124	112/7206	4.66970204046e-07
ko04072	Phospholipase D signaling pathway	58/1124	197/7206	6.72036528066e-07
ko04720	Long-term potentiation	35/1124	99/7206	9.95759814547e-07
ko04261	Adrenergic signaling in cardiomyocytes	59/1124	205/7206	1.16645105541e-06
ko05031	Amphetamine addiction	33/1124	91/7206	1.1811765146e-06
ko04022	cGMP-PKG signaling pathway	61/1124	216/7206	1.43602059718e-06
ko04742	Taste transduction	25/1124	61/7206	1.55420810127e-06
ko04925	Aldosterone synthesis and secretion	35/1124	105/7206	4.82467868776e-06
ko04971	Gastric acid secretion	33/1124	98/7206	7.58883963342e-06
ko04972	Pancreatic secretion	36/1124	111/7206	8.06015325176e-06
ko04730	Long-term depression	28/1124	78/7206	9.90491725594e-06
ko04110	Cell cycle	6/1124	145/7206	2.25065284031e-05
ko04710	Circadian rhythm	18/1124	43/7206	3.21893643392e-05
ko04514	Cell adhesion molecules (CAMs)	38/1124	130/7206	7.14730473568e-05
ko05203	Viral carcinogenesis	22/1124	277/7206	0.000182007109137
ko04014	Ras signaling pathway	66/1124	279/7206	0.000373300057778
ko04976	Bile secretion	25/1124	80/7206	0.000471779905072
ko04120	Ubiquitin mediated proteolysis	8/1124	138/7206	0.000539095842694
ko05030	Cocaine addiction	23/1124	73/7206	0.000541795941623
ko04750	Inflammatory mediator regulation of TRP channels	34/1124	122/7206	0.00055913162362
ko04010	MAPK signaling pathway	72/1124	321/7206	0.000916793703372
ko04666	Fc gamma R-mediated phagocytosis	33/1124	122/7206	0.000971459952125
ko05016	Huntington's disease	17/1124	215/7206	0.00108231623518
ko04141	Protein processing in endoplasmic reticulum	14/1124	184/7206	0.0013697493521
ko04711	Circadian rhythm - fly	7/1124	13/7206	0.00159025787901
ko03050	Proteasome	1/1124	54/7206	0.00205589538889
ko04744	Phototransduction	13/1124	36/7206	0.00207816261114
ko00520	Amino sugar and nucleotide sugar metabolism	1/1124	55/7206	0.00215022223798
ko00562	Inositol phosphate metabolism	25/1124	89/7206	0.00279917962928
ko04964	Proximal tubule bicarbonate reclamation	11/1124	29/7206	0.00289961631245
ko04966	Collecting duct acid secretion	10/1124	26/7206	0.00397372768566
ko04745	Phototransduction - fly	13/1124	38/7206	0.00516157482115
ko05231	Choline metabolism in cancer	33/1124	134/7206	0.00552424558621
ko04360	Axon guidance	52/1124	233/7206	0.00574390271579
ko04540	Gap junction	32/1124	128/7206	0.00633476559903
ko04270	Vascular smooth muscle contraction	37/1124	154/7206	0.006620703259
ko04924	Renin secretion	23/1124	86/7206	0.00675956985339
ko03420	Nucleotide excision repair	1/1124	46/7206	0.00691126300362
ko05110	Vibrio cholerae infection	18/1124	63/7206	0.0079868238044
ko05168	Herpes simplex infection	16/1124	182/7206	0.00931751210872
ko04922	Glucagon signaling pathway	31/1124	128/7206	0.00954553452713
ko05014	Amyotrophic lateral sclerosis (ALS)	20/1124	74/7206	0.00971514998732
ko04371	Apelin signaling pathway	40/1124	177/7206	0.0117637694208
ko00280	Valine, leucine and isoleucine degradation	2/1124	54/7206	0.0127728530755
ko04623	Cytosolic DNA-sensing pathway	1/1124	41/7206	0.0155333029217
ko04923	Regulation of lipolysis in adipocytes	20/1124	77/7206	0.0169838285319
ko05164	Influenza A	15/1124	167/7206	0.017027159742
ko04621	NOD-like receptor signaling pathway	14/1124	157/7206	0.0189764336642
ko03410	Base excision repair	1/1124	38/7206	0.0229269766334
ko05133	Pertussis	6/1124	87/7206	0.0245077621499
ko05130	Pathogenic Escherichia coli infection	5/1124	77/7206	0.0258620076902
ko05219	Bladder cancer	2/1124	48/7206	0.0262722002269
ko00120	Primary bile acid biosynthesis	7/1124	20/7206	0.026562115732
ko04960	Aldosterone-regulated sodium reabsorption	12/1124	41/7206	0.027377843225
ko04350	TGF-beta signaling pathway	8/1124	103/7206	0.0276313116813
ko04915	Estrogen signaling pathway	30/1124	131/7206	0.0277795706573
ko04062	Chemokine signaling pathway	43/1124	201/7206	0.0294240310148
ko04932	Non-alcoholic fatty liver disease (NAFLD)	18/1124	182/7206	0.029686579369
ko03015	mRNA surveillance pathway	7/1124	93/7206	0.0300885468378
ko05169	Epstein-Barr virus infection	21/1124	206/7206	0.0315500924472
ko04650	Natural killer cell mediated cytotoxicity	23/1124	97/7206	0.0337213094226
ko04115	p53 signaling pathway	5/1124	74/7206	0.0351174522749
ko04260	Cardiac muscle contraction	23/1124	98/7206	0.0354746671988
ko05222	Small cell lung cancer	7/1124	89/7206	0.0398511525855
ko04015	Rap1 signaling pathway	56/1124	278/7206	0.0425308534913
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/1124	79/7206	0.04274541889
ko02010	ABC transporters	11/1124	39/7206	0.0428838052189
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1124	59/7206	0.0460982117417
ko04113	Meiosis - yeast	5/1124	70/7206	0.0474143442712
ko04919	Thyroid hormone signaling pathway	31/1124	143/7206	0.0477225187612
ko00564	Glycerophospholipid metabolism	23/1124	99/7206	0.049191129694
ko04626	Plant-pathogen interaction	6/1124	18/7206	0.0492920379777