ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 37/173 145/7206 1.18591042728e-28 ko03030 DNA replication 21/173 38/7206 5.74263092656e-25 ko03460 Fanconi anemia pathway 17/173 51/7206 9.65354886517e-16 ko03410 Base excision repair 14/173 38/7206 7.30776873253e-14 ko03440 Homologous recombination 14/173 41/7206 2.50166126827e-13 ko04110 Cell cycle 23/173 145/7206 3.31151728114e-13 ko04111 Cell cycle - yeast 17/173 90/7206 2.71592584106e-11 ko03420 Nucleotide excision repair 12/173 46/7206 4.79244670281e-10 ko00240 Pyrimidine metabolism 16/173 110/7206 5.97449330217e-09 ko03430 Mismatch repair 8/173 22/7206 2.25402157079e-08 ko04113 Meiosis - yeast 11/173 70/7206 7.0393110807e-07 ko05168 Herpes simplex infection 14/173 182/7206 0.000112175331534 ko00230 Purine metabolism 13/173 194/7206 0.00075285121137 ko03015 mRNA surveillance pathway 8/173 93/7206 0.00168457883779 ko03013 RNA transport 11/173 166/7206 0.00209211077742 ko04218 Cellular senescence 11/173 177/7206 0.00345042416372 ko05222 Small cell lung cancer 7/173 89/7206 0.00536916348822 ko04010 MAPK signaling pathway 1/173 321/7206 0.00748832455987 ko04115 p53 signaling pathway 6/173 74/7206 0.00844474609665 ko04024 cAMP signaling pathway 1/173 279/7206 0.015127353697 ko03022 Basal transcription factors 4/173 44/7206 0.0206473914198 ko04810 Regulation of actin cytoskeleton 1/173 264/7206 0.0220151908721 ko05205 Proteoglycans in cancer 1/173 271/7206 0.0228552768266 ko05166 HTLV-I infection 13/173 292/7206 0.0291638655418 ko04510 Focal adhesion 1/173 240/7206 0.0314634973982 ko05203 Viral carcinogenesis 12/173 277/7206 0.0426379085545 ko04120 Ubiquitin mediated proteolysis 7/173 138/7206 0.0479542508615 ko03450 Non-homologous end-joining 2/173 15/7206 0.0490265431436