ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	138/656	423/7206	1.89655187311e-45
ko05033	Nicotine addiction	45/656	56/7206	2.04071790453e-37
ko04724	Glutamatergic synapse	65/656	152/7206	4.99115322787e-29
ko05032	Morphine addiction	48/656	110/7206	4.05042113555e-22
ko04727	GABAergic synapse	46/656	110/7206	2.59519578081e-20
ko04728	Dopaminergic synapse	60/656	185/7206	1.55121401446e-19
ko04723	Retrograde endocannabinoid signaling	57/656	175/7206	1.05419005021e-18
ko04721	Synaptic vesicle cycle	37/656	80/7206	2.36639997795e-18
ko04713	Circadian entrainment	49/656	136/7206	2.73145738346e-18
ko04024	cAMP signaling pathway	70/656	279/7206	7.36384595484e-16
ko04725	Cholinergic synapse	45/656	160/7206	2.03063557413e-12
ko04726	Serotonergic synapse	40/656	137/7206	9.78044279512e-12
ko04742	Taste transduction	25/656	61/7206	2.30014990658e-11
ko05030	Cocaine addiction	27/656	73/7206	6.21488002233e-11
ko05031	Amphetamine addiction	30/656	91/7206	1.49102969869e-10
ko04911	Insulin secretion	34/656	117/7206	4.19460647922e-10
ko05014	Amyotrophic lateral sclerosis (ALS)	26/656	74/7206	5.26195456214e-10
ko04720	Long-term potentiation	30/656	99/7206	1.50634814088e-09
ko04261	Adrenergic signaling in cardiomyocytes	43/656	205/7206	1.69626001249e-07
ko04060	Cytokine-cytokine receptor interaction	1/656	191/7206	3.12870404268e-07
ko04020	Calcium signaling pathway	50/656	265/7206	5.36530813804e-07
ko04970	Salivary secretion	25/656	95/7206	7.26743688487e-07
ko04921	Oxytocin signaling pathway	39/656	209/7206	1.25770089444e-05
ko04730	Long-term depression	20/656	78/7206	1.4283026181e-05
ko04010	MAPK signaling pathway	53/656	321/7206	1.52604664337e-05
ko03040	Spliceosome	1/656	145/7206	2.64738325689e-05
ko05164	Influenza A	2/656	167/7206	2.9737838286e-05
ko05203	Viral carcinogenesis	8/656	277/7206	6.42933239448e-05
ko05034	Alcoholism	40/656	238/7206	0.000124599272897
ko04514	Cell adhesion molecules (CAMs)	26/656	130/7206	0.000141486486494
ko04915	Estrogen signaling pathway	26/656	131/7206	0.000149826736289
ko04744	Phototransduction	11/656	36/7206	0.000235668612862
ko05168	Herpes simplex infection	4/656	182/7206	0.000333462422813
ko04972	Pancreatic secretion	22/656	111/7206	0.000373865318036
ko04120	Ubiquitin mediated proteolysis	2/656	138/7206	0.000437689273513
ko04971	Gastric acid secretion	20/656	98/7206	0.000513222606787
ko04014	Ras signaling pathway	43/656	279/7206	0.000595925899263
ko04022	cGMP-PKG signaling pathway	35/656	216/7206	0.000670825762592
ko05205	Proteoglycans in cancer	10/656	271/7206	0.000759507602114
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/656	14/7206	0.000882378611727
ko03013	RNA transport	4/656	166/7206	0.000895917320431
ko04740	Olfactory transduction	17/656	80/7206	0.0011669802567
ko04966	Collecting duct acid secretion	8/656	26/7206	0.00160170143531
ko04621	NOD-like receptor signaling pathway	4/656	157/7206	0.00176804512548
ko05162	Measles	2/656	120/7206	0.00190340750745
ko05169	Epstein-Barr virus infection	7/656	206/7206	0.00196139350109
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/656	59/7206	0.00206855962395
ko04540	Gap junction	22/656	128/7206	0.00295425748065
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/656	182/7206	0.00369293247401
ko04260	Cardiac muscle contraction	18/656	98/7206	0.00376847549248
ko00240	Pyrimidine metabolism	2/656	110/7206	0.00384221716594
ko04146	Peroxisome	1/656	89/7206	0.00436994240625
ko04110	Cell cycle	4/656	145/7206	0.00493024289053
ko04360	Axon guidance	34/656	233/7206	0.00518216815468
ko04350	TGF-beta signaling pathway	2/656	103/7206	0.00540047915042
ko03018	RNA degradation	1/656	84/7206	0.00630234955123
ko05166	HTLV-I infection	14/656	292/7206	0.00671277550535
ko04924	Renin secretion	16/656	86/7206	0.00674404214943
ko05146	Amoebiasis	2/656	99/7206	0.00772624901681
ko04072	Phospholipase D signaling pathway	29/656	197/7206	0.00815535802686
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/656	15/7206	0.00853280222549
ko04141	Protein processing in endoplasmic reticulum	7/656	184/7206	0.00882254710287
ko04612	Antigen processing and presentation	1/656	77/7206	0.00894555768843
ko04925	Aldosterone synthesis and secretion	18/656	105/7206	0.00895169347777
ko03008	Ribosome biogenesis in eukaryotes	1/656	79/7206	0.00911174704477
ko05322	Systemic lupus erythematosus	5/656	151/7206	0.00931960331061
ko01200	Carbon metabolism	4/656	128/7206	0.0125761526411
ko00310	Lysine degradation	1/656	73/7206	0.0130877184309
ko04214	Apoptosis - fly	1/656	72/7206	0.0130985914819
ko00512	Mucin type O-glycan biosynthesis	7/656	29/7206	0.0132416733377
ko04964	Proximal tubule bicarbonate reclamation	7/656	29/7206	0.0132416733377
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	14/656	79/7206	0.015669047911
ko04745	Phototransduction - fly	8/656	38/7206	0.0189621142115
ko04626	Plant-pathogen interaction	5/656	18/7206	0.0193722514302
ko04371	Apelin signaling pathway	25/656	177/7206	0.0240119836587
ko04071	Sphingolipid signaling pathway	23/656	162/7206	0.0271264400096
ko05110	Vibrio cholerae infection	11/656	63/7206	0.0277636415151
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/656	8/7206	0.0296917982523
ko04138	Autophagy - yeast	2/656	81/7206	0.0315359236459
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	6/656	28/7206	0.0369898267514
ko04962	Vasopressin-regulated water reabsorption	10/656	58/7206	0.038679057416
ko01212	Fatty acid metabolism	1/656	60/7206	0.0405355481485
ko00330	Arginine and proline metabolism	1/656	61/7206	0.0410008253101
ko00561	Glycerolipid metabolism	1/656	63/7206	0.0429249518721
ko04015	Rap1 signaling pathway	35/656	278/7206	0.0433175692698
ko01524	Platinum drug resistance	2/656	76/7206	0.0444266473934
ko04064	NF-kappa B signaling pathway	3/656	96/7206	0.0464370326482
ko04976	Bile secretion	13/656	80/7206	0.0467743081803