ko pathway ratio_in_study ratio_in_pop p_value ko04974 Protein digestion and absorption 16/173 96/7206 7.58949028203e-10 ko04978 Mineral absorption 10/173 40/7206 2.23090246295e-08 ko04260 Cardiac muscle contraction 14/173 98/7206 7.04413528638e-08 ko00250 Alanine, aspartate and glutamate metabolism 8/173 38/7206 2.48236500149e-06 ko04261 Adrenergic signaling in cardiomyocytes 17/173 205/7206 7.48631068745e-06 ko01200 Carbon metabolism 13/173 128/7206 1.07502789572e-05 ko04972 Pancreatic secretion 12/173 111/7206 1.25190427849e-05 ko04976 Bile secretion 10/173 80/7206 1.89029192606e-05 ko04971 Gastric acid secretion 11/173 98/7206 2.03612356234e-05 ko04270 Vascular smooth muscle contraction 13/173 154/7206 7.71584330775e-05 ko04371 Apelin signaling pathway 14/173 177/7206 8.30645873836e-05 ko00983 Drug metabolism - other enzymes 6/173 42/7206 0.000449360209222 ko04921 Oxytocin signaling pathway 14/173 209/7206 0.000473772760203 ko04964 Proximal tubule bicarbonate reclamation 5/173 29/7206 0.000559965597389 ko05200 Pathways in cancer 2/173 492/7206 0.0006733935365 ko00620 Pyruvate metabolism 6/173 46/7206 0.00074120123731 ko04614 Renin-angiotensin system 4/173 18/7206 0.00075444589752 ko00380 Tryptophan metabolism 6/173 50/7206 0.00116171700922 ko00100 Steroid biosynthesis 4/173 21/7206 0.00139490514444 ko04152 AMPK signaling pathway 11/173 161/7206 0.00163927966597 ko04020 Calcium signaling pathway 15/173 265/7206 0.00169809552483 ko00630 Glyoxylate and dicarboxylate metabolism 5/173 38/7206 0.00198826259219 ko04022 cGMP-PKG signaling pathway 13/173 216/7206 0.0020089687418 ko05410 Hypertrophic cardiomyopathy (HCM) 8/173 100/7206 0.00267134148497 ko00830 Retinol metabolism 5/173 42/7206 0.00311931540479 ko00040 Pentose and glucuronate interconversions 4/173 26/7206 0.00317347613642 ko00680 Methane metabolism 4/173 34/7206 0.00848359165487 ko00640 Propanoate metabolism 4/173 34/7206 0.00848359165487 ko04975 Fat digestion and absorption 4/173 35/7206 0.00940241619584 ko05416 Viral myocarditis 5/173 55/7206 0.00993822067891 ko01212 Fatty acid metabolism 5/173 60/7206 0.0141815044671 ko00591 Linoleic acid metabolism 3/173 22/7206 0.0149734193777 ko00053 Ascorbate and aldarate metabolism 3/173 22/7206 0.0149734193777 ko05203 Viral carcinogenesis 1/173 277/7206 0.0150699319661 ko04924 Renin secretion 6/173 86/7206 0.0169560450194 ko00561 Glycerolipid metabolism 5/173 63/7206 0.0172373505073 ko04144 Endocytosis 2/173 342/7206 0.0175865788999 ko04973 Carbohydrate digestion and absorption 4/173 42/7206 0.0176622977687 ko00220 Arginine biosynthesis 3/173 24/7206 0.0190040628104 ko03320 PPAR signaling pathway 5/173 69/7206 0.0245918755958 ko00710 Carbon fixation in photosynthetic organisms 3/173 27/7206 0.0260666871265 ko04970 Salivary secretion 6/173 95/7206 0.0263171645123 ko05204 Chemical carcinogenesis 4/173 48/7206 0.0275008816401 ko00260 Glycine, serine and threonine metabolism 4/173 48/7206 0.0275008816401 ko00010 Glycolysis / Gluconeogenesis 5/173 74/7206 0.0320656791704 ko04922 Glucagon signaling pathway 7/173 128/7206 0.0340349204125 ko00280 Valine, leucine and isoleucine degradation 4/173 54/7206 0.0400573453988 ko00030 Pentose phosphate pathway 3/173 32/7206 0.0405358395106 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5/173 79/7206 0.0408242527442 ko00052 Galactose metabolism 3/173 33/7206 0.0438268611812 ko00860 Porphyrin and chlorophyll metabolism 3/173 34/7206 0.0472471775868 ko00254 Aflatoxin biosynthesis 1/173 2/7206 0.0474424216231 ko05034 Alcoholism 1/173 238/7206 0.0475336128542 ko05166 HTLV-I infection 2/173 292/7206 0.049013648981