ko pathway ratio_in_study ratio_in_pop p_value ko00190 Oxidative phosphorylation 46/332 127/7206 5.32245566379e-30 ko05012 Parkinson's disease 46/332 155/7206 1.09816291568e-25 ko05010 Alzheimer's disease 51/332 202/7206 8.55273340171e-25 ko05016 Huntington's disease 48/332 215/7206 7.13144827e-21 ko04260 Cardiac muscle contraction 31/332 98/7206 1.7925073862e-18 ko04932 Non-alcoholic fatty liver disease (NAFLD) 35/332 182/7206 2.37396056614e-13 ko05410 Hypertrophic cardiomyopathy (HCM) 24/332 100/7206 1.20382875543e-11 ko01200 Carbon metabolism 27/332 128/7206 1.56811749036e-11 ko00010 Glycolysis / Gluconeogenesis 19/332 74/7206 5.11509066923e-10 ko05414 Dilated cardiomyopathy 23/332 112/7206 9.33548833576e-10 ko04974 Protein digestion and absorption 21/332 96/7206 1.51948407695e-09 ko04723 Retrograde endocannabinoid signaling 28/332 175/7206 5.4895054218e-09 ko00020 Citrate cycle (TCA cycle) 12/332 35/7206 2.40550318671e-08 ko04512 ECM-receptor interaction 17/332 79/7206 7.43111914745e-08 ko04510 Focal adhesion 30/332 240/7206 4.77861304861e-07 ko04261 Adrenergic signaling in cardiomyocytes 27/332 205/7206 6.47482263726e-07 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 15/332 79/7206 2.39548496145e-06 ko01230 Biosynthesis of amino acids 14/332 85/7206 2.86651191089e-05 ko00710 Carbon fixation in photosynthetic organisms 7/332 27/7206 0.000165189143858 ko00620 Pyruvate metabolism 9/332 46/7206 0.000203843725619 ko05034 Alcoholism 1/332 238/7206 0.000231619114121 ko04020 Calcium signaling pathway 26/332 265/7206 0.000242342371582 ko00680 Methane metabolism 7/332 34/7206 0.000757656043099 ko05416 Viral myocarditis 9/332 55/7206 0.000816350362045 ko00250 Alanine, aspartate and glutamate metabolism 7/332 38/7206 0.00151706235801 ko04964 Proximal tubule bicarbonate reclamation 6/332 29/7206 0.0017643274401 ko05203 Viral carcinogenesis 3/332 277/7206 0.00182799708003 ko05152 Tuberculosis 1/332 187/7206 0.00229522528597 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/332 191/7206 0.00235391577903 ko00030 Pentose phosphate pathway 6/332 32/7206 0.00299591156309 ko00350 Tyrosine metabolism 6/332 33/7206 0.00352255560196 ko04921 Oxytocin signaling pathway 19/332 209/7206 0.00396091895922 ko00220 Arginine biosynthesis 5/332 24/7206 0.00414848657771 ko00500 Starch and sucrose metabolism 6/332 35/7206 0.00477808992908 ko05161 Hepatitis B 1/332 173/7206 0.00495538535894 ko04071 Sphingolipid signaling pathway 1/332 162/7206 0.00709271434921 ko04022 cGMP-PKG signaling pathway 19/332 216/7206 0.0071672774058 ko04140 Autophagy - animal 1/332 164/7206 0.00717729435435 ko03013 RNA transport 1/332 166/7206 0.00733090199541 ko04151 PI3K-Akt signaling pathway 29/332 390/7206 0.00896860378391 ko04724 Glutamatergic synapse 1/332 152/7206 0.0102598591976 ko00280 Valine, leucine and isoleucine degradation 7/332 54/7206 0.0113521275541 ko04728 Dopaminergic synapse 2/332 185/7206 0.012477613997 ko04110 Cell cycle 1/332 145/7206 0.0149132983254 ko00330 Arginine and proline metabolism 7/332 61/7206 0.0212943972143 ko04120 Ubiquitin mediated proteolysis 1/332 138/7206 0.021770595573 ko05164 Influenza A 2/332 167/7206 0.0247791753756 ko03010 Ribosome 1/332 129/7206 0.0313141328517 ko05230 Central carbon metabolism in cancer 8/332 81/7206 0.0322746966109 ko04722 Neurotrophin signaling pathway 2/332 160/7206 0.0347524566236 ko04550 Signaling pathways regulating pluripotency of stem cells 2/332 165/7206 0.0357357702441 ko00051 Fructose and mannose metabolism 5/332 42/7206 0.0423950078967 ko04668 TNF signaling pathway 1/332 120/7206 0.0449547224715 ko04211 Longevity regulating pathway 1/332 123/7206 0.0462109823326 ko04660 T cell receptor signaling pathway 1/332 124/7206 0.0468012256353 ko04150 mTOR signaling pathway 3/332 184/7206 0.0488941461562