ko pathway ratio_in_study ratio_in_pop p_value ko03440 Homologous recombination 24/299 41/7206 2.18910506665e-23 ko04110 Cell cycle 38/299 145/7206 7.39150074852e-21 ko03460 Fanconi anemia pathway 22/299 51/7206 9.66531569782e-18 ko04111 Cell cycle - yeast 25/299 90/7206 1.06319116738e-14 ko03040 Spliceosome 31/299 145/7206 1.72283754408e-14 ko04113 Meiosis - yeast 17/299 70/7206 2.18740071692e-09 ko03013 RNA transport 24/299 166/7206 7.03702256163e-08 ko03410 Base excision repair 11/299 38/7206 2.30750076218e-07 ko03030 DNA replication 11/299 38/7206 2.30750076218e-07 ko04114 Oocyte meiosis 20/299 139/7206 9.74096546818e-07 ko03420 Nucleotide excision repair 10/299 46/7206 1.40401821032e-05 ko03430 Mismatch repair 7/299 22/7206 1.96613359748e-05 ko00240 Pyrimidine metabolism 15/299 110/7206 4.34504326498e-05 ko04144 Endocytosis 2/299 342/7206 7.79832478426e-05 ko03008 Ribosome biogenesis in eukaryotes 12/299 79/7206 8.80758404325e-05 ko04218 Cellular senescence 19/299 177/7206 0.000125645044337 ko03018 RNA degradation 12/299 84/7206 0.000161405293834 ko00310 Lysine degradation 11/299 73/7206 0.000186328243063 ko04115 p53 signaling pathway 11/299 74/7206 0.000210925879064 ko04020 Calcium signaling pathway 1/299 265/7206 0.000233231894396 ko04914 Progesterone-mediated oocyte maturation 13/299 104/7206 0.000339741620434 ko04151 PI3K-Akt signaling pathway 4/299 390/7206 0.000366778017535 ko03022 Basal transcription factors 8/299 44/7206 0.000384326809946 ko05166 HTLV-I infection 24/299 292/7206 0.00133262392446 ko03450 Non-homologous end-joining 4/299 15/7206 0.00275780088113 ko04261 Adrenergic signaling in cardiomyocytes 1/299 205/7206 0.00357195094268 ko04010 MAPK signaling pathway 4/299 321/7206 0.00388600945503 ko03015 mRNA surveillance pathway 10/299 93/7206 0.00497617522222 ko04024 cAMP signaling pathway 3/299 279/7206 0.00514351155082 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/299 182/7206 0.00723576928664 ko04728 Dopaminergic synapse 1/299 185/7206 0.00745696367064 ko04723 Retrograde endocannabinoid signaling 1/299 175/7206 0.0107548300307 ko04371 Apelin signaling pathway 1/299 177/7206 0.0110482339667 ko04014 Ras signaling pathway 4/299 279/7206 0.0139966032608 ko04725 Cholinergic synapse 1/299 160/7206 0.014992741146 ko04510 Focal adhesion 3/299 240/7206 0.0194118242967 ko04015 Rap1 signaling pathway 4/299 278/7206 0.0197673969098 ko04724 Glutamatergic synapse 1/299 152/7206 0.0217805563413 ko05012 Parkinson's disease 1/299 155/7206 0.0222761647713 ko04621 NOD-like receptor signaling pathway 1/299 157/7206 0.0227959087771 ko04530 Tight junction 3/299 228/7206 0.0264281386632 ko05142 Chagas disease (American trypanosomiasis) 1/299 130/7206 0.0447884283465 ko04915 Estrogen signaling pathway 1/299 131/7206 0.0448559340294 ko04933 AGE-RAGE signaling pathway in diabetic complications 1/299 135/7206 0.0458296872892 ko04713 Circadian entrainment 1/299 136/7206 0.0462479551408 ko04726 Serotonergic synapse 1/299 137/7206 0.0467357825801 ko04910 Insulin signaling pathway 2/299 172/7206 0.0496862159026 ko04921 Oxytocin signaling pathway 3/299 209/7206 0.0499859628029