ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	73/707	152/7206	1.71488410358e-34
ko04080	Neuroactive ligand-receptor interaction	128/707	423/7206	1.91803087311e-34
ko05033	Nicotine addiction	42/707	56/7206	2.24118637273e-31
ko04727	GABAergic synapse	57/707	110/7206	2.62232869958e-29
ko05032	Morphine addiction	54/707	110/7206	2.70623857366e-26
ko04723	Retrograde endocannabinoid signaling	64/707	175/7206	3.25529282419e-22
ko04713	Circadian entrainment	55/707	136/7206	1.20245736601e-21
ko04728	Dopaminergic synapse	60/707	185/7206	6.49451598941e-18
ko04744	Phototransduction	25/707	36/7206	8.83241235242e-18
ko04726	Serotonergic synapse	45/707	137/7206	6.18573966042e-14
ko04725	Cholinergic synapse	48/707	160/7206	4.21814653171e-13
ko04020	Calcium signaling pathway	63/707	265/7206	1.06177660754e-11
ko04024	cAMP signaling pathway	65/707	279/7206	1.73608145999e-11
ko04721	Synaptic vesicle cycle	30/707	80/7206	2.37182584937e-11
ko04911	Insulin secretion	37/707	117/7206	3.98664402486e-11
ko04742	Taste transduction	25/707	61/7206	1.18221471602e-10
ko04261	Adrenergic signaling in cardiomyocytes	49/707	205/7206	2.28644460336e-09
ko04921	Oxytocin signaling pathway	49/707	209/7206	3.95457732677e-09
ko05031	Amphetamine addiction	28/707	91/7206	1.92907268139e-08
ko04720	Long-term potentiation	29/707	99/7206	3.67490578669e-08
ko05030	Cocaine addiction	24/707	73/7206	4.84607447361e-08
ko04970	Salivary secretion	28/707	95/7206	5.46478676444e-08
ko04010	MAPK signaling pathway	61/707	321/7206	2.47190589655e-07
ko04740	Olfactory transduction	24/707	80/7206	3.40441128726e-07
ko05203	Viral carcinogenesis	6/707	277/7206	5.15014192677e-07
ko04072	Phospholipase D signaling pathway	40/707	197/7206	7.52934443624e-06
ko04730	Long-term depression	21/707	78/7206	1.22704040097e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	19/707	74/7206	6.47477792001e-05
ko04925	Aldosterone synthesis and secretion	24/707	105/7206	7.64092207396e-05
ko04110	Cell cycle	2/707	145/7206	9.43700446503e-05
ko04972	Pancreatic secretion	24/707	111/7206	0.000157815780769
ko05164	Influenza A	4/707	167/7206	0.00030663937556
ko04022	cGMP-PKG signaling pathway	38/707	216/7206	0.000413081290452
ko04260	Cardiac muscle contraction	21/707	98/7206	0.000467804236482
ko04971	Gastric acid secretion	21/707	98/7206	0.000467804236482
ko04070	Phosphatidylinositol signaling system	23/707	112/7206	0.000562645702947
ko05169	Epstein-Barr virus infection	7/707	206/7206	0.000759242659959
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/707	79/7206	0.000774389326512
ko05162	Measles	2/707	120/7206	0.000888706106182
ko04141	Protein processing in endoplasmic reticulum	6/707	184/7206	0.000997132331287
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/707	182/7206	0.00140021149408
ko05414	Dilated cardiomyopathy	22/707	112/7206	0.00187728503885
ko04060	Cytokine-cytokine receptor interaction	7/707	191/7206	0.00190381562223
ko04514	Cell adhesion molecules (CAMs)	24/707	130/7206	0.00244317641917
ko04745	Phototransduction - fly	10/707	38/7206	0.00287343086486
ko00562	Inositol phosphate metabolism	18/707	89/7206	0.00320563137104
ko05205	Proteoglycans in cancer	13/707	271/7206	0.00333949666633
ko04120	Ubiquitin mediated proteolysis	4/707	138/7206	0.00338718890711
ko05322	Systemic lupus erythematosus	5/707	151/7206	0.00348547686214
ko05168	Herpes simplex infection	7/707	182/7206	0.0035024927062
ko05130	Pathogenic Escherichia coli infection	1/707	77/7206	0.00600074749825
ko04610	Complement and coagulation cascades	1/707	79/7206	0.00633318572164
ko04915	Estrogen signaling pathway	23/707	131/7206	0.00677220716514
ko04014	Ras signaling pathway	41/707	279/7206	0.00742115921482
ko05034	Alcoholism	36/707	238/7206	0.00757210283555
ko04150	mTOR signaling pathway	8/707	184/7206	0.00812215627424
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/707	14/7206	0.00844964280147
ko00240	Pyrimidine metabolism	3/707	110/7206	0.00869320662324
ko04621	NOD-like receptor signaling pathway	6/707	157/7206	0.00914988486174
ko04540	Gap junction	22/707	128/7206	0.0097256316275
ko04371	Apelin signaling pathway	28/707	177/7206	0.0100348002207
ko04062	Chemokine signaling pathway	31/707	201/7206	0.0109200212335
ko04550	Signaling pathways regulating pluripotency of stem cells	7/707	165/7206	0.0114273497907
ko03013	RNA transport	7/707	166/7206	0.0114909348072
ko04350	TGF-beta signaling pathway	3/707	103/7206	0.01185899359
ko03320	PPAR signaling pathway	1/707	69/7206	0.0129508981914
ko03018	RNA degradation	2/707	84/7206	0.0153830806551
ko04640	Hematopoietic cell lineage	1/707	64/7206	0.0187302550267
ko04964	Proximal tubule bicarbonate reclamation	7/707	29/7206	0.0194267901057
ko04810	Regulation of actin cytoskeleton	15/707	264/7206	0.0199443615517
ko04750	Inflammatory mediator regulation of TRP channels	20/707	122/7206	0.0201807661903
ko03008	Ribosome biogenesis in eukaryotes	2/707	79/7206	0.0218183505821
ko05145	Toxoplasmosis	5/707	126/7206	0.0225821054467
ko05131	Shigellosis	2/707	82/7206	0.0226433563689
ko04658	Th1 and Th2 cell differentiation	3/707	96/7206	0.0232670272354
ko05410	Hypertrophic cardiomyopathy (HCM)	17/707	100/7206	0.0255127324382
ko04142	Lysosome	7/707	151/7206	0.0266462098917
ko04670	Leukocyte transendothelial migration	7/707	151/7206	0.0266462098917
ko05231	Choline metabolism in cancer	21/707	134/7206	0.0272874460403
ko01212	Fatty acid metabolism	1/707	60/7206	0.0273782085926
ko04210	Apoptosis	9/707	180/7206	0.0297985191592
ko05140	Leishmaniasis	2/707	75/7206	0.0309378492764
ko04145	Phagosome	8/707	162/7206	0.0321253134484
ko00910	Nitrogen metabolism	5/707	19/7206	0.0325447160098
ko04710	Circadian rhythm	9/707	43/7206	0.033092554317
ko05202	Transcriptional misregulation in cancer	10/707	188/7206	0.0341728387235
ko04510	Focal adhesion	14/707	240/7206	0.0353517446741
ko04930	Type II diabetes mellitus	10/707	54/7206	0.0387026022634
ko05416	Viral myocarditis	1/707	55/7206	0.0396997639553
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/707	59/7206	0.0429977519138
ko04666	Fc gamma R-mediated phagocytosis	19/707	122/7206	0.0438401040952
ko04214	Apoptosis - fly	2/707	72/7206	0.0440891964972
ko04657	IL-17 signaling pathway	3/707	87/7206	0.0444440715039
ko05133	Pertussis	3/707	87/7206	0.0444440715039
ko00310	Lysine degradation	2/707	73/7206	0.0447568773992
ko04146	Peroxisome	3/707	89/7206	0.0456312694887