ko pathway ratio_in_study ratio_in_pop p_value ko04110 Cell cycle 36/184 145/7206 2.04311879884e-26 ko04111 Cell cycle - yeast 21/184 90/7206 4.16301452018e-15 ko03410 Base excision repair 11/184 38/7206 1.47393000298e-09 ko03030 DNA replication 11/184 38/7206 1.47393000298e-09 ko04113 Meiosis - yeast 13/184 70/7206 1.70835652083e-08 ko05322 Systemic lupus erythematosus 18/184 151/7206 4.34815275487e-08 ko03008 Ribosome biogenesis in eukaryotes 12/184 79/7206 6.17521478338e-07 ko04218 Cellular senescence 17/184 177/7206 2.3455027682e-06 ko05034 Alcoholism 20/184 238/7206 2.40033210088e-06 ko00240 Pyrimidine metabolism 13/184 110/7206 3.90802117877e-06 ko05202 Transcriptional misregulation in cancer 17/184 188/7206 5.36272841353e-06 ko04114 Oocyte meiosis 13/184 139/7206 5.02532792195e-05 ko05203 Viral carcinogenesis 19/184 277/7206 7.6608033906e-05 ko04115 p53 signaling pathway 9/184 74/7206 0.000100280991548 ko05166 HTLV-I infection 19/184 292/7206 0.000154199970933 ko03040 Spliceosome 12/184 145/7206 0.000313760740425 ko05206 MicroRNAs in cancer 13/184 177/7206 0.00056687173742 ko05222 Small cell lung cancer 8/184 89/7206 0.00187688917053 ko03430 Mismatch repair 4/184 22/7206 0.00209873842271 ko04144 Endocytosis 1/184 342/7206 0.00231356284319 ko04010 MAPK signaling pathway 1/184 321/7206 0.00335631454838 ko03440 Homologous recombination 5/184 41/7206 0.00365489840555 ko04914 Progesterone-mediated oocyte maturation 8/184 104/7206 0.00495342227423 ko03420 Nucleotide excision repair 5/184 46/7206 0.00603412693304 ko04024 cAMP signaling pathway 1/184 279/7206 0.010487859219 ko04014 Ras signaling pathway 1/184 279/7206 0.010487859219 ko05224 Breast cancer 10/184 174/7206 0.0134183088608 ko04810 Regulation of actin cytoskeleton 1/184 264/7206 0.0152525148627 ko00230 Purine metabolism 10/184 194/7206 0.0327078789184 ko04510 Focal adhesion 1/184 240/7206 0.0332467052134 ko05219 Bladder cancer 4/184 48/7206 0.0334519240968 ko03460 Fanconi anemia pathway 4/184 51/7206 0.040529198457 ko05161 Hepatitis B 9/184 173/7206 0.0435255070472 ko04022 cGMP-PKG signaling pathway 1/184 216/7206 0.045683906008 ko04151 PI3K-Akt signaling pathway 4/184 390/7206 0.0468039159838 ko04350 TGF-beta signaling pathway 6/184 103/7206 0.0476983967867 ko04015 Rap1 signaling pathway 2/184 278/7206 0.0495455690269