ko pathway ratio_in_study ratio_in_pop p_value ko04713 Circadian entrainment 18/181 136/7206 6.28808882868e-09 ko04724 Glutamatergic synapse 18/181 152/7206 3.73211276626e-08 ko04725 Cholinergic synapse 17/181 160/7206 4.46327031209e-07 ko04744 Phototransduction 8/181 36/7206 2.25042802415e-06 ko04728 Dopaminergic synapse 17/181 185/7206 3.4402598347e-06 ko04745 Phototransduction - fly 8/181 38/7206 3.48387204755e-06 ko04371 Apelin signaling pathway 16/181 177/7206 8.35538275025e-06 ko04921 Oxytocin signaling pathway 17/181 209/7206 1.76653561663e-05 ko04721 Synaptic vesicle cycle 10/181 80/7206 2.79867983836e-05 ko04740 Olfactory transduction 10/181 80/7206 2.79867983836e-05 ko04626 Plant-pathogen interaction 5/181 18/7206 6.21400633633e-05 ko00190 Oxidative phosphorylation 12/181 127/7206 7.60020834652e-05 ko04726 Serotonergic synapse 12/181 137/7206 0.000157939474193 ko04911 Insulin secretion 11/181 117/7206 0.000158997630753 ko00680 Methane metabolism 6/181 34/7206 0.000173106253172 ko04966 Collecting duct acid secretion 5/181 26/7206 0.000405214570209 ko05031 Amphetamine addiction 9/181 91/7206 0.000434450410446 ko00010 Glycolysis / Gluconeogenesis 8/181 74/7206 0.000496721599682 ko04261 Adrenergic signaling in cardiomyocytes 14/181 205/7206 0.00061527521393 ko04720 Long-term potentiation 9/181 99/7206 0.000807986088187 ko05110 Vibrio cholerae infection 7/181 63/7206 0.00094799890458 ko04922 Glucagon signaling pathway 10/181 128/7206 0.00136410813613 ko04723 Retrograde endocannabinoid signaling 12/181 175/7206 0.00145357741856 ko05010 Alzheimer's disease 13/181 202/7206 0.00165529884917 ko05032 Morphine addiction 9/181 110/7206 0.00171186066285 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/181 92/7206 0.00209151437338 ko04024 cAMP signaling pathway 16/181 279/7206 0.0023936778587 ko04970 Salivary secretion 8/181 95/7206 0.00256275589115 ko04066 HIF-1 signaling pathway 9/181 123/7206 0.00367358612581 ko00051 Fructose and mannose metabolism 5/181 42/7206 0.00378868452661 ko04062 Chemokine signaling pathway 12/181 201/7206 0.00458247205983 ko04925 Aldosterone synthesis and secretion 8/181 105/7206 0.00475624319219 ko01230 Biosynthesis of amino acids 7/181 85/7206 0.0053302838848 ko04727 GABAergic synapse 8/181 110/7206 0.00628794178652 ko05323 Rheumatoid arthritis 7/181 89/7206 0.00684447535217 ko04152 AMPK signaling pathway 10/181 161/7206 0.0071690839442 ko05152 Tuberculosis 11/181 187/7206 0.00729775574122 ko04020 Calcium signaling pathway 14/181 265/7206 0.0077356545333 ko04360 Axon guidance 13/181 233/7206 0.00810118097468 ko04971 Gastric acid secretion 7/181 98/7206 0.0113926472491 ko04912 GnRH signaling pathway 8/181 122/7206 0.011474192508 ko04022 cGMP-PKG signaling pathway 12/181 216/7206 0.0118150168107 ko05033 Nicotine addiction 5/181 56/7206 0.0128415676289 ko04730 Long-term depression 6/181 78/7206 0.0133229952895 ko05214 Glioma 6/181 79/7206 0.0141263239875 ko01200 Carbon metabolism 8/181 128/7206 0.015017638402 ko04014 Ras signaling pathway 14/181 279/7206 0.0164176300402 ko05034 Alcoholism 12/181 238/7206 0.0185966550599 ko04722 Neurotrophin signaling pathway 9/181 160/7206 0.0191392991201 ko04145 Phagosome 9/181 162/7206 0.0205756752304 ko04710 Circadian rhythm 4/181 43/7206 0.0221722597145 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/181 1/7206 0.0251179572578 ko04916 Melanogenesis 8/181 142/7206 0.026275135531 ko04260 Cardiac muscle contraction 6/181 98/7206 0.0363528382385 ko05410 Hypertrophic cardiomyopathy (HCM) 6/181 100/7206 0.0395370286776 ko04514 Cell adhesion molecules (CAMs) 7/181 130/7206 0.0449117893068 ko00030 Pentose phosphate pathway 3/181 32/7206 0.0453699494134