ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 15/131 134/7206 1.52909014131e-08 ko04668 TNF signaling pathway 13/131 120/7206 2.18485047142e-07 ko05164 Influenza A 15/131 167/7206 2.95346114942e-07 ko04060 Cytokine-cytokine receptor interaction 16/131 191/7206 3.02831136947e-07 ko04621 NOD-like receptor signaling pathway 12/131 157/7206 2.54636284437e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/131 191/7206 3.97196006612e-05 ko04620 Toll-like receptor signaling pathway 9/131 100/7206 7.74894487997e-05 ko04660 T cell receptor signaling pathway 10/131 124/7206 7.87500830049e-05 ko04210 Apoptosis 12/131 180/7206 9.74389832154e-05 ko05160 Hepatitis C 11/131 153/7206 9.80357792951e-05 ko04630 Jak-STAT signaling pathway 10/131 132/7206 0.000133187126777 ko05161 Hepatitis B 11/131 173/7206 0.000290680795756 ko05162 Measles 9/131 120/7206 0.000313742939132 ko04064 NF-kappa B signaling pathway 8/131 96/7206 0.000333761781067 ko04623 Cytosolic DNA-sensing pathway 5/131 41/7206 0.000815288982227 ko00051 Fructose and mannose metabolism 5/131 42/7206 0.000912129483186 ko04657 IL-17 signaling pathway 7/131 87/7206 0.000976119906482 ko04662 B cell receptor signaling pathway 7/131 88/7206 0.00104468836721 ko04217 Necroptosis 10/131 178/7206 0.00143387529646 ko05168 Herpes simplex infection 10/131 182/7206 0.00169408110479 ko04932 Non-alcoholic fatty liver disease (NAFLD) 10/131 182/7206 0.00169408110479 ko05132 Salmonella infection 7/131 98/7206 0.00195982536538 ko05142 Chagas disease (American trypanosomiasis) 8/131 130/7206 0.00244307618881 ko04931 Insulin resistance 8/131 137/7206 0.00338242989005 ko04062 Chemokine signaling pathway 10/131 201/7206 0.00350338575371 ko05131 Shigellosis 6/131 82/7206 0.00364310304029 ko04672 Intestinal immune network for IgA production 4/131 37/7206 0.00432983068037 ko04917 Prolactin signaling pathway 6/131 87/7206 0.00488123088137 ko04622 RIG-I-like receptor signaling pathway 5/131 62/7206 0.00519655486111 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/131 92/7206 0.00640448023537 ko05145 Toxoplasmosis 7/131 126/7206 0.00787576925874 ko05134 Legionellosis 5/131 74/7206 0.010888183467 ko04933 AGE-RAGE signaling pathway in diabetic complications 7/131 135/7206 0.0112965506447 ko01524 Platinum drug resistance 5/131 76/7206 0.0121348829101 ko05418 Fluid shear stress and atherosclerosis 8/131 173/7206 0.0132978984237 ko05215 Prostate cancer 6/131 111/7206 0.0153993821373 ko05230 Central carbon metabolism in cancer 5/131 81/7206 0.0156679656265 ko04930 Type II diabetes mellitus 4/131 54/7206 0.0163698700923 ko05152 Tuberculosis 8/131 187/7206 0.0203492647752 ko05133 Pertussis 5/131 87/7206 0.0207420590802 ko05166 HTLV-I infection 11/131 292/7206 0.0211755787878 ko05323 Rheumatoid arthritis 5/131 89/7206 0.0226464684251 ko04920 Adipocytokine signaling pathway 5/131 89/7206 0.0226464684251 ko04211 Longevity regulating pathway 6/131 123/7206 0.0242672431935 ko04722 Neurotrophin signaling pathway 7/131 160/7206 0.026283641958 ko05221 Acute myeloid leukemia 4/131 63/7206 0.0272341700522 ko04658 Th1 and Th2 cell differentiation 5/131 96/7206 0.0301919685968 ko04650 Natural killer cell mediated cytotoxicity 5/131 97/7206 0.0313845920423 ko04068 FoxO signaling pathway 7/131 167/7206 0.0321759160294 ko04080 Neuroactive ligand-receptor interaction 2/131 423/7206 0.0357118707573 ko05140 Leishmaniasis 4/131 75/7206 0.0471479581746