ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	176/1038	423/7206	1.31500509127e-45
ko05033	Nicotine addiction	45/1038	56/7206	1.77177974755e-28
ko04724	Glutamatergic synapse	79/1038	152/7206	2.29743737313e-28
ko05032	Morphine addiction	62/1038	110/7206	5.32219135747e-25
ko04713	Circadian entrainment	67/1038	136/7206	1.77170643399e-22
ko04727	GABAergic synapse	59/1038	110/7206	2.40663871529e-22
ko04728	Dopaminergic synapse	78/1038	185/7206	1.13786155772e-20
ko04725	Cholinergic synapse	68/1038	160/7206	2.25234380293e-18
ko04723	Retrograde endocannabinoid signaling	71/1038	175/7206	8.54125183256e-18
ko04020	Calcium signaling pathway	92/1038	265/7206	2.23370143567e-17
ko04721	Synaptic vesicle cycle	43/1038	80/7206	1.18961739426e-16
ko04024	cAMP signaling pathway	91/1038	279/7206	4.05286297218e-15
ko04911	Insulin secretion	50/1038	117/7206	6.16517885858e-14
ko04726	Serotonergic synapse	54/1038	137/7206	3.37593947046e-13
ko04742	Taste transduction	33/1038	61/7206	3.50580255823e-13
ko04744	Phototransduction	24/1038	36/7206	1.1050538525e-12
ko04921	Oxytocin signaling pathway	70/1038	209/7206	1.4798237489e-12
ko04261	Adrenergic signaling in cardiomyocytes	67/1038	205/7206	2.0096040795e-11
ko05031	Amphetamine addiction	38/1038	91/7206	1.53083036887e-10
ko04970	Salivary secretion	38/1038	95/7206	6.87630020597e-10
ko03040	Spliceosome	1/1038	145/7206	5.64333324456e-09
ko05203	Viral carcinogenesis	11/1038	277/7206	1.34821525344e-08
ko04720	Long-term potentiation	36/1038	99/7206	3.81473052438e-08
ko04360	Axon guidance	65/1038	233/7206	5.99473158488e-08
ko05322	Systemic lupus erythematosus	4/1038	151/7206	1.73896034327e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1038	74/7206	1.7833013925e-06
ko04740	Olfactory transduction	28/1038	80/7206	2.9930475722e-06
ko04925	Aldosterone synthesis and secretion	34/1038	105/7206	3.42314983425e-06
ko04514	Cell adhesion molecules (CAMs)	39/1038	130/7206	3.58597023309e-06
ko04971	Gastric acid secretion	32/1038	98/7206	3.58757650912e-06
ko04070	Phosphatidylinositol signaling system	35/1038	112/7206	4.1661876997e-06
ko05030	Cocaine addiction	26/1038	73/7206	4.6496243207e-06
ko04060	Cytokine-cytokine receptor interaction	8/1038	191/7206	5.3728742236e-06
ko04022	cGMP-PKG signaling pathway	56/1038	216/7206	7.00035188902e-06
ko04010	MAPK signaling pathway	75/1038	321/7206	1.3638888918e-05
ko05168	Herpes simplex infection	8/1038	182/7206	1.51601373562e-05
ko03013	RNA transport	7/1038	166/7206	2.7548168065e-05
ko05164	Influenza A	7/1038	167/7206	2.78919118427e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1038	79/7206	2.79218342046e-05
ko04745	Phototransduction - fly	16/1038	38/7206	2.98561015045e-05
ko04730	Long-term depression	25/1038	78/7206	6.0723951042e-05
ko04924	Renin secretion	27/1038	86/7206	6.51680864443e-05
ko04621	NOD-like receptor signaling pathway	7/1038	157/7206	7.72397738352e-05
ko04260	Cardiac muscle contraction	29/1038	98/7206	0.000109737402569
ko04120	Ubiquitin mediated proteolysis	6/1038	138/7206	0.000199552983123
ko04141	Protein processing in endoplasmic reticulum	11/1038	184/7206	0.000407227040891
ko04972	Pancreatic secretion	30/1038	111/7206	0.000520886370878
ko05414	Dilated cardiomyopathy	30/1038	112/7206	0.000562945052802
ko05169	Epstein-Barr virus infection	14/1038	206/7206	0.000835573156284
ko04612	Antigen processing and presentation	2/1038	77/7206	0.000934647473117
ko04610	Complement and coagulation cascades	2/1038	79/7206	0.000976262478653
ko03008	Ribosome biogenesis in eukaryotes	2/1038	79/7206	0.000976262478653
ko05205	Proteoglycans in cancer	21/1038	271/7206	0.00102584362103
ko04750	Inflammatory mediator regulation of TRP channels	31/1038	122/7206	0.00106435345274
ko04014	Ras signaling pathway	60/1038	279/7206	0.00120720920199
ko04540	Gap junction	32/1038	128/7206	0.00132682226902
ko00562	Inositol phosphate metabolism	24/1038	89/7206	0.00196333761426
ko04966	Collecting duct acid secretion	10/1038	26/7206	0.0021734893714
ko04072	Phospholipase D signaling pathway	44/1038	197/7206	0.00264293374876
ko05161	Hepatitis B	12/1038	173/7206	0.00295364619738
ko00480	Glutathione metabolism	1/1038	55/7206	0.00325441834346
ko05162	Measles	7/1038	120/7206	0.0053989166265
ko04146	Peroxisome	4/1038	89/7206	0.00551046163126
ko04976	Bile secretion	21/1038	80/7206	0.00560837894711
ko04711	Circadian rhythm - fly	6/1038	13/7206	0.00610073168343
ko05140	Leishmaniasis	3/1038	75/7206	0.00721495437166
ko04064	NF-kappa B signaling pathway	5/1038	96/7206	0.00768862770914
ko04110	Cell cycle	10/1038	145/7206	0.00806360739744
ko00330	Arginine and proline metabolism	2/1038	61/7206	0.00915887319858
ko05410	Hypertrophic cardiomyopathy (HCM)	24/1038	100/7206	0.00931847248876
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1038	14/7206	0.00939247896891
ko04626	Plant-pathogen interaction	7/1038	18/7206	0.00939899068961
ko04330	Notch signaling pathway	2/1038	62/7206	0.00949274730854
ko05166	HTLV-I infection	27/1038	292/7206	0.0104019437364
ko00620	Pyruvate metabolism	1/1038	46/7206	0.0107585158493
ko03420	Nucleotide excision repair	1/1038	46/7206	0.0107585158493
ko04630	Jak-STAT signaling pathway	9/1038	132/7206	0.0116232878471
ko04973	Carbohydrate digestion and absorption	12/1038	42/7206	0.0143201518569
ko03022	Basal transcription factors	1/1038	44/7206	0.016095156044
ko04915	Estrogen signaling pathway	29/1038	131/7206	0.0162772067515
ko04722	Neurotrophin signaling pathway	34/1038	160/7206	0.0164686635265
ko00071	Fatty acid degradation	1/1038	45/7206	0.0166102353792
ko04371	Apelin signaling pathway	37/1038	177/7206	0.0167083977503
ko05016	Huntington's disease	19/1038	215/7206	0.0175428517348
ko05110	Vibrio cholerae infection	16/1038	63/7206	0.0182789408209
ko00280	Valine, leucine and isoleucine degradation	2/1038	54/7206	0.0188204256395
ko04350	TGF-beta signaling pathway	7/1038	103/7206	0.023375500806
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/1038	59/7206	0.0236288578451
ko00140	Steroid hormone biosynthesis	1/1038	41/7206	0.0238057870835
ko04710	Circadian rhythm	12/1038	43/7206	0.0257116573212
ko03018	RNA degradation	5/1038	84/7206	0.0271238134181
ko00310	Lysine degradation	4/1038	73/7206	0.0279923597986
ko04964	Proximal tubule bicarbonate reclamation	9/1038	29/7206	0.0281510847993
ko04622	RIG-I-like receptor signaling pathway	3/1038	62/7206	0.0281553670678
ko04115	p53 signaling pathway	4/1038	74/7206	0.0285728094032
ko04930	Type II diabetes mellitus	14/1038	54/7206	0.0293277556351
ko04932	Non-alcoholic fatty liver disease (NAFLD)	16/1038	182/7206	0.0316976715057
ko00630	Glyoxylate and dicarboxylate metabolism	1/1038	38/7206	0.0351558540175
ko05219	Bladder cancer	2/1038	48/7206	0.0387675762036
ko05145	Toxoplasmosis	10/1038	126/7206	0.039531968891
ko04960	Aldosterone-regulated sodium reabsorption	11/1038	41/7206	0.0401136087347
ko04657	IL-17 signaling pathway	6/1038	87/7206	0.0450619245271
ko05133	Pertussis	6/1038	87/7206	0.0450619245271
ko04142	Lysosome	13/1038	151/7206	0.0454313484607