ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 46/379 145/7206 1.47927182881e-24 ko03440 Homologous recombination 22/379 41/7206 3.90347388277e-18 ko03013 RNA transport 38/379 166/7206 3.97112876989e-15 ko04110 Cell cycle 35/379 145/7206 9.17052920222e-15 ko03460 Fanconi anemia pathway 21/379 51/7206 2.14255419567e-14 ko04111 Cell cycle - yeast 25/379 90/7206 2.40994227139e-12 ko04113 Meiosis - yeast 18/379 70/7206 1.18367029461e-08 ko03022 Basal transcription factors 14/379 44/7206 2.64521954739e-08 ko04144 Endocytosis 3/379 342/7206 1.6914534316e-05 ko03410 Base excision repair 10/379 38/7206 1.80609725433e-05 ko03008 Ribosome biogenesis in eukaryotes 14/379 79/7206 5.29408157778e-05 ko03018 RNA degradation 14/379 84/7206 0.000106202385871 ko03030 DNA replication 9/379 38/7206 0.000116978162467 ko04151 PI3K-Akt signaling pathway 6/379 390/7206 0.000164320515372 ko04024 cAMP signaling pathway 3/379 279/7206 0.000308963711286 ko03015 mRNA surveillance pathway 14/379 93/7206 0.000322306743586 ko04114 Oocyte meiosis 18/379 139/7206 0.000332189701687 ko05010 Alzheimer's disease 1/379 202/7206 0.000334821580388 ko03420 Nucleotide excision repair 9/379 46/7206 0.000544152145247 ko00240 Pyrimidine metabolism 15/379 110/7206 0.000593400047903 ko03020 RNA polymerase 7/379 29/7206 0.00059999851479 ko03430 Mismatch repair 6/379 22/7206 0.000739017576885 ko04914 Progesterone-mediated oocyte maturation 14/379 104/7206 0.00102074454632 ko04921 Oxytocin signaling pathway 2/379 209/7206 0.00147110249854 ko04022 cGMP-PKG signaling pathway 2/379 216/7206 0.00156724636671 ko04510 Focal adhesion 3/379 240/7206 0.00178462785576 ko04261 Adrenergic signaling in cardiomyocytes 2/379 205/7206 0.00214233532504 ko05322 Systemic lupus erythematosus 17/379 151/7206 0.00260163661605 ko04621 NOD-like receptor signaling pathway 1/379 157/7206 0.00329613107633 ko04724 Glutamatergic synapse 1/379 152/7206 0.00489860965512 ko04218 Cellular senescence 18/379 177/7206 0.00600895721132 ko03450 Non-homologous end-joining 4/379 15/7206 0.0064704474331 ko04728 Dopaminergic synapse 2/379 185/7206 0.0064757834086 ko05205 Proteoglycans in cancer 5/379 271/7206 0.00764818320748 ko05203 Viral carcinogenesis 25/379 277/7206 0.00829837478994 ko04723 Retrograde endocannabinoid signaling 2/379 175/7206 0.00890871811624 ko04371 Apelin signaling pathway 2/379 177/7206 0.00914622349605 ko04530 Tight junction 4/379 228/7206 0.0101111259598 ko04713 Circadian entrainment 1/379 136/7206 0.0102453207012 ko04360 Axon guidance 4/379 233/7206 0.010266025451 ko04810 Regulation of actin cytoskeleton 5/379 264/7206 0.0104863844068 ko04015 Rap1 signaling pathway 6/379 278/7206 0.0132849983437 ko04014 Ras signaling pathway 6/379 279/7206 0.0132946466622 ko00190 Oxidative phosphorylation 1/379 127/7206 0.0147003159111 ko01200 Carbon metabolism 1/379 128/7206 0.0147936437304 ko04115 p53 signaling pathway 9/379 74/7206 0.014970686545 ko05166 HTLV-I infection 25/379 292/7206 0.0151598716395 ko05012 Parkinson's disease 2/379 155/7206 0.0173933388273 ko04725 Cholinergic synapse 2/379 160/7206 0.0179031091312 ko04120 Ubiquitin mediated proteolysis 14/379 138/7206 0.0181695112618 ko05152 Tuberculosis 3/379 187/7206 0.0187963497495 ko04911 Insulin secretion 1/379 117/7206 0.0211816533319 ko04668 TNF signaling pathway 1/379 120/7206 0.0213335850261 ko04750 Inflammatory mediator regulation of TRP channels 1/379 122/7206 0.0217355826299 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/379 182/7206 0.026561524751 ko03060 Protein export 4/379 23/7206 0.0301406142392 ko04727 GABAergic synapse 1/379 110/7206 0.0305432130649 ko04072 Phospholipase D signaling pathway 4/379 197/7206 0.034776757398 ko05418 Fluid shear stress and atherosclerosis 3/379 173/7206 0.0361278818546 ko05200 Pathways in cancer 16/379 492/7206 0.0362912431936 ko04659 Th17 cell differentiation 1/379 106/7206 0.0447868184525 ko04390 Hippo signaling pathway 4/379 188/7206 0.0468765033273 ko04915 Estrogen signaling pathway 2/379 131/7206 0.0480445845336 ko04630 Jak-STAT signaling pathway 2/379 132/7206 0.0480649756963 ko04152 AMPK signaling pathway 3/379 161/7206 0.0484741384007 ko04611 Platelet activation 3/379 163/7206 0.0487934482271 ko04931 Insulin resistance 2/379 137/7206 0.049574684516 ko04726 Serotonergic synapse 2/379 137/7206 0.049574684516