ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	26/300	80/7206	4.4275597951e-17
ko05033	Nicotine addiction	19/300	56/7206	3.51638712361e-13
ko04713	Circadian entrainment	27/300	136/7206	6.4929018906e-12
ko04911	Insulin secretion	25/300	117/7206	7.35359465201e-12
ko04744	Phototransduction	14/300	36/7206	5.7794552946e-11
ko04728	Dopaminergic synapse	30/300	185/7206	9.00214684536e-11
ko04724	Glutamatergic synapse	27/300	152/7206	9.76252736497e-11
ko04261	Adrenergic signaling in cardiomyocytes	31/300	205/7206	2.66640101586e-10
ko04727	GABAergic synapse	22/300	110/7206	5.44051029829e-10
ko04970	Salivary secretion	20/300	95/7206	1.31439652852e-09
ko04024	cAMP signaling pathway	34/300	279/7206	1.16830598582e-08
ko05032	Morphine addiction	20/300	110/7206	1.91096054261e-08
ko04723	Retrograde endocannabinoid signaling	24/300	175/7206	2.08058068705e-07
ko04966	Collecting duct acid secretion	9/300	26/7206	5.57319718988e-07
ko05110	Vibrio cholerae infection	12/300	63/7206	8.61274523987e-06
ko05120	Epithelial cell signaling in Helicobacter pylori infection	14/300	92/7206	2.32346839207e-05
ko04080	Neuroactive ligand-receptor interaction	36/300	423/7206	4.06373276251e-05
ko05030	Cocaine addiction	12/300	73/7206	4.08413053386e-05
ko04972	Pancreatic secretion	15/300	111/7206	5.02868847347e-05
ko05031	Amphetamine addiction	13/300	91/7206	8.94012314934e-05
ko04725	Cholinergic synapse	18/300	160/7206	0.000108045364185
ko04260	Cardiac muscle contraction	13/300	98/7206	0.000192866847697
ko04971	Gastric acid secretion	13/300	98/7206	0.000192866847697
ko04720	Long-term potentiation	13/300	99/7206	0.000213877559522
ko04022	cGMP-PKG signaling pathway	21/300	216/7206	0.000328854000037
ko04726	Serotonergic synapse	15/300	137/7206	0.000540463237964
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/300	59/7206	0.000667739585495
ko05014	Amyotrophic lateral sclerosis (ALS)	10/300	74/7206	0.000907466376711
ko04964	Proximal tubule bicarbonate reclamation	6/300	29/7206	0.00104507134738
ko05323	Rheumatoid arthritis	11/300	89/7206	0.00108957506169
ko00190	Oxidative phosphorylation	13/300	127/7206	0.00231672535087
ko04924	Renin secretion	10/300	86/7206	0.00288205279801
ko04921	Oxytocin signaling pathway	18/300	209/7206	0.00390353460997
ko04145	Phagosome	15/300	162/7206	0.00391352026016
ko04745	Phototransduction - fly	6/300	38/7206	0.00443524919816
ko04730	Long-term depression	9/300	78/7206	0.00486007480338
ko05203	Viral carcinogenesis	3/300	277/7206	0.00510481080594
ko04626	Plant-pathogen interaction	4/300	18/7206	0.00567030728806
ko04978	Mineral absorption	6/300	40/7206	0.00575240147996
ko04960	Aldosterone-regulated sodium reabsorption	6/300	41/7206	0.00650855259824
ko05034	Alcoholism	19/300	238/7206	0.00706437607897
ko05168	Herpes simplex infection	1/300	182/7206	0.00726865112485
ko04973	Carbohydrate digestion and absorption	6/300	42/7206	0.00733438840376
ko04940	Type I diabetes mellitus	5/300	32/7206	0.00966171927241
ko05164	Influenza A	1/300	167/7206	0.0103550454313
ko04020	Calcium signaling pathway	20/300	265/7206	0.0108235104453
ko04371	Apelin signaling pathway	15/300	177/7206	0.0111481038657
ko05010	Alzheimer's disease	16/300	202/7206	0.0115498391799
ko04976	Bile secretion	8/300	80/7206	0.0176872615664
ko04740	Olfactory transduction	8/300	80/7206	0.0176872615664
ko05205	Proteoglycans in cancer	4/300	271/7206	0.0191414548307
ko04510	Focal adhesion	3/300	240/7206	0.0195384813039
ko04014	Ras signaling pathway	20/300	279/7206	0.020118817549
ko02024	Quorum sensing	3/300	15/7206	0.0224028167544
ko04514	Cell adhesion molecules (CAMs)	11/300	130/7206	0.0230731649354
ko04060	Cytokine-cytokine receptor interaction	2/300	191/7206	0.0253594733293
ko04918	Thyroid hormone synthesis	8/300	86/7206	0.0261808125162
ko04810	Regulation of actin cytoskeleton	4/300	264/7206	0.026325603632
ko04062	Chemokine signaling pathway	15/300	201/7206	0.0288143146755
ko04120	Ubiquitin mediated proteolysis	1/300	138/7206	0.0311697063443
ko05166	HTLV-I infection	5/300	292/7206	0.0343337377848
ko04925	Aldosterone synthesis and secretion	9/300	105/7206	0.0414975244806
ko02025	Biofilm formation - Pseudomonas aeruginosa	1/300	1/7206	0.0416319733557
ko00230	Purine metabolism	14/300	194/7206	0.0422830587783
ko04010	MAPK signaling pathway	21/300	321/7206	0.0432914781284
ko04630	Jak-STAT signaling pathway	1/300	132/7206	0.0450687128396
ko04016	MAPK signaling pathway - plant	3/300	20/7206	0.0481994641607