ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 18/183 134/7206 5.893109357e-09 ko04060 Cytokine-cytokine receptor interaction 19/183 191/7206 3.06243831855e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/183 191/7206 1.4194601118e-06 ko04668 TNF signaling pathway 13/183 120/7206 9.73390854936e-06 ko05152 Tuberculosis 16/183 187/7206 1.92802097752e-05 ko04666 Fc gamma R-mediated phagocytosis 12/183 122/7206 5.69842405133e-05 ko04145 Phagosome 14/183 162/7206 5.82837474708e-05 ko05323 Rheumatoid arthritis 10/183 89/7206 7.7991854452e-05 ko05164 Influenza A 14/183 167/7206 8.12673202869e-05 ko04650 Natural killer cell mediated cytotoxicity 10/183 97/7206 0.000161851495513 ko05132 Salmonella infection 10/183 98/7206 0.000176335934149 ko04137 Mitophagy - animal 9/183 82/7206 0.000214165784079 ko04672 Intestinal immune network for IgA production 6/183 37/7206 0.000298304880949 ko04142 Lysosome 12/183 151/7206 0.00043339297254 ko04630 Jak-STAT signaling pathway 11/183 132/7206 0.000502501949925 ko04062 Chemokine signaling pathway 14/183 201/7206 0.000564080952266 ko04217 Necroptosis 13/183 178/7206 0.000567889556936 ko05140 Leishmaniasis 8/183 75/7206 0.000585535103907 ko04621 NOD-like receptor signaling pathway 12/183 157/7206 0.000616774358014 ko04064 NF-kappa B signaling pathway 9/183 96/7206 0.000698724877191 ko04610 Complement and coagulation cascades 8/183 79/7206 0.000830652569877 ko05144 Malaria 6/183 45/7206 0.000883319014987 ko04620 Toll-like receptor signaling pathway 9/183 100/7206 0.000939833289106 ko00120 Primary bile acid biosynthesis 4/183 20/7206 0.00141771387664 ko05161 Hepatitis B 12/183 173/7206 0.0014471585839 ko05150 Staphylococcus aureus infection 5/183 36/7206 0.00198946707174 ko05321 Inflammatory bowel disease (IBD) 6/183 56/7206 0.00279665602465 ko05162 Measles 9/183 120/7206 0.003349530894 ko05166 HTLV-I infection 16/183 292/7206 0.00344300373039 ko04623 Cytosolic DNA-sensing pathway 5/183 41/7206 0.00357041637693 ko04660 T cell receptor signaling pathway 9/183 124/7206 0.00416885647476 ko05418 Fluid shear stress and atherosclerosis 11/183 173/7206 0.00444668565641 ko05131 Shigellosis 7/183 82/7206 0.00464207080167 ko05133 Pertussis 7/183 87/7206 0.00641926214431 ko04215 Apoptosis - multiple species 5/183 47/7206 0.00646717251638 ko05340 Primary immunodeficiency 4/183 30/7206 0.00658106820328 ko04080 Neuroactive ligand-receptor interaction 3/183 423/7206 0.00974453328303 ko04664 Fc epsilon RI signaling pathway 6/183 77/7206 0.0131979068007 ko04670 Leukocyte transendothelial migration 9/183 151/7206 0.0144913117523 ko05145 Toxoplasmosis 8/183 126/7206 0.0146220960409 ko05160 Hepatitis C 9/183 153/7206 0.015678920749 ko04622 RIG-I-like receptor signaling pathway 5/183 62/7206 0.0201381033902 ko05169 Epstein-Barr virus infection 11/183 206/7206 0.0202062010082 ko00051 Fructose and mannose metabolism 4/183 42/7206 0.0212518073527 ko04933 AGE-RAGE signaling pathway in diabetic complications 8/183 135/7206 0.0213043517453 ko04611 Platelet activation 9/183 163/7206 0.022714525179 ko04662 B cell receptor signaling pathway 6/183 88/7206 0.0240444441513 ko04810 Regulation of actin cytoskeleton 13/183 264/7206 0.0247055367949 ko04210 Apoptosis 10/183 180/7206 0.0253030040568 ko04966 Collecting duct acid secretion 3/183 26/7206 0.0272780655991 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/183 92/7206 0.0291422520983 ko05100 Bacterial invasion of epithelial cells 6/183 99/7206 0.0396799164447 ko05146 Amoebiasis 6/183 99/7206 0.0396799164447 ko01524 Platinum drug resistance 5/183 76/7206 0.0434290861297 ko05130 Pathogenic Escherichia coli infection 5/183 77/7206 0.0455284735834 ko04612 Antigen processing and presentation 5/183 77/7206 0.0455284735834