ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	87/751	145/7206	1.9985330284e-49
ko05322	Systemic lupus erythematosus	67/751	151/7206	1.72208194948e-27
ko04110	Cell cycle	62/751	145/7206	2.00588200714e-24
ko03440	Homologous recombination	32/751	41/7206	2.87138851034e-24
ko03013	RNA transport	65/751	166/7206	5.39512297757e-23
ko03460	Fanconi anemia pathway	32/751	51/7206	1.42810508102e-19
ko04111	Cell cycle - yeast	43/751	90/7206	1.56535912594e-19
ko03030	DNA replication	27/751	38/7206	7.79752289628e-19
ko05034	Alcoholism	69/751	238/7206	4.3008414373e-16
ko03008	Ribosome biogenesis in eukaryotes	35/751	79/7206	7.48315049839e-15
ko04113	Meiosis - yeast	31/751	70/7206	2.70830974401e-13
ko03430	Mismatch repair	16/751	22/7206	6.82141878201e-12
ko03420	Nucleotide excision repair	23/751	46/7206	1.49965547034e-11
ko04020	Calcium signaling pathway	2/751	265/7206	1.12401877841e-10
ko00240	Pyrimidine metabolism	36/751	110/7206	1.37757134949e-10
ko04144	Endocytosis	6/751	342/7206	2.74538049387e-10
ko05203	Viral carcinogenesis	64/751	277/7206	5.54072738777e-10
ko03018	RNA degradation	27/751	84/7206	4.41840516222e-08
ko03410	Base excision repair	17/751	38/7206	5.89584646124e-08
ko04024	cAMP signaling pathway	6/751	279/7206	1.14495273381e-07
ko03015	mRNA surveillance pathway	28/751	93/7206	1.20301898029e-07
ko04060	Cytokine-cytokine receptor interaction	2/751	191/7206	2.42955560732e-07
ko04151	PI3K-Akt signaling pathway	14/751	390/7206	5.57153798017e-07
ko03022	Basal transcription factors	17/751	44/7206	7.67987008799e-07
ko04621	NOD-like receptor signaling pathway	1/751	157/7206	9.33675432922e-07
ko04724	Glutamatergic synapse	1/751	152/7206	1.38252219243e-06
ko05012	Parkinson's disease	1/751	155/7206	1.5023305853e-06
ko04723	Retrograde endocannabinoid signaling	2/751	175/7206	1.86158682319e-06
ko03020	RNA polymerase	13/751	29/7206	2.14296232807e-06
ko05010	Alzheimer's disease	4/751	202/7206	5.766343058e-06
ko04022	cGMP-PKG signaling pathway	5/751	216/7206	7.13151342486e-06
ko04713	Circadian entrainment	1/751	136/7206	1.13310861862e-05
ko04270	Vascular smooth muscle contraction	2/751	154/7206	1.24206093061e-05
ko04510	Focal adhesion	7/751	240/7206	1.37464959731e-05
ko04921	Oxytocin signaling pathway	5/751	209/7206	1.48810999665e-05
ko04010	MAPK signaling pathway	13/751	321/7206	3.2945107109e-05
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/751	182/7206	3.54962641296e-05
ko04725	Cholinergic synapse	3/751	160/7206	3.83583282223e-05
ko04911	Insulin secretion	1/751	117/7206	5.18533400154e-05
ko04668	TNF signaling pathway	1/751	120/7206	5.43016970464e-05
ko04261	Adrenergic signaling in cardiomyocytes	6/751	205/7206	6.78094101e-05
ko04014	Ras signaling pathway	11/751	279/7206	8.39943741418e-05
ko04062	Chemokine signaling pathway	6/751	201/7206	9.5243812734e-05
ko04727	GABAergic synapse	1/751	110/7206	0.000114676327238
ko05032	Morphine addiction	1/751	110/7206	0.000114676327238
ko05414	Dilated cardiomyopathy	1/751	112/7206	0.000118820242706
ko04728	Dopaminergic synapse	5/751	185/7206	0.000122115340589
ko04514	Cell adhesion molecules (CAMs)	2/751	130/7206	0.00012348441508
ko05145	Toxoplasmosis	2/751	126/7206	0.000180431610777
ko00190	Oxidative phosphorylation	2/751	127/7206	0.000182524390873
ko04015	Rap1 signaling pathway	12/751	278/7206	0.000276599891664
ko04726	Serotonergic synapse	3/751	137/7206	0.000346558937749
ko05152	Tuberculosis	6/751	187/7206	0.000366803457394
ko04260	Cardiac muscle contraction	1/751	98/7206	0.000376571136833
ko05410	Hypertrophic cardiomyopathy (HCM)	1/751	100/7206	0.000383917943947
ko03450	Non-homologous end-joining	7/751	15/7206	0.000394252970713
ko04380	Osteoclast differentiation	3/751	134/7206	0.000500083047168
ko04970	Salivary secretion	1/751	95/7206	0.000558753564491
ko04114	Oocyte meiosis	28/751	139/7206	0.00060429923982
ko04611	Platelet activation	5/751	163/7206	0.000655364257635
ko04371	Apelin signaling pathway	6/751	177/7206	0.00069968452014
ko04915	Estrogen signaling pathway	3/751	131/7206	0.00072744588302
ko04152	AMPK signaling pathway	5/751	161/7206	0.000937699860102
ko04360	Axon guidance	10/751	233/7206	0.000965865330694
ko04914	Progesterone-mediated oocyte maturation	22/751	104/7206	0.00100792732234
ko04920	Adipocytokine signaling pathway	1/751	89/7206	0.00126698173282
ko04530	Tight junction	10/751	228/7206	0.00128484064717
ko04218	Cellular senescence	32/751	177/7206	0.00166851857597
ko04072	Phospholipase D signaling pathway	8/751	197/7206	0.00188452714811
ko04810	Regulation of actin cytoskeleton	13/751	264/7206	0.00191882832196
ko04924	Renin secretion	1/751	86/7206	0.00193331545158
ko05166	HTLV-I infection	47/751	292/7206	0.00228351709827
ko04630	Jak-STAT signaling pathway	4/751	132/7206	0.00231266225208
ko05202	Transcriptional misregulation in cancer	33/751	188/7206	0.00233077101358
ko04971	Gastric acid secretion	2/751	98/7206	0.00246557365292
ko04620	Toll-like receptor signaling pathway	2/751	100/7206	0.00251082081305
ko00230	Purine metabolism	34/751	194/7206	0.00260509751661
ko04922	Glucagon signaling pathway	4/751	128/7206	0.00323624216327
ko05140	Leishmaniasis	1/751	75/7206	0.00393501822596
ko04660	T cell receptor signaling pathway	4/751	124/7206	0.00451615843789
ko05031	Amphetamine addiction	2/751	91/7206	0.00513076555734
ko05030	Cocaine addiction	1/751	73/7206	0.00590710762272
ko00010	Glycolysis / Gluconeogenesis	1/751	74/7206	0.00608309020184
ko04912	GnRH signaling pathway	4/751	122/7206	0.00641303295752
ko04750	Inflammatory mediator regulation of TRP channels	4/751	122/7206	0.00641303295752
ko04120	Ubiquitin mediated proteolysis	25/751	138/7206	0.00676374715097
ko04918	Thyroid hormone synthesis	2/751	86/7206	0.00735384429382
ko05133	Pertussis	2/751	87/7206	0.00736560667195
ko04146	Peroxisome	2/751	89/7206	0.00762700203977
ko05418	Fluid shear stress and atherosclerosis	8/751	173/7206	0.0079594220126
ko05142	Chagas disease (American trypanosomiasis)	5/751	130/7206	0.00881168337117
ko05205	Proteoglycans in cancer	16/751	271/7206	0.0110071851511
ko05132	Salmonella infection	3/751	98/7206	0.0116582371085
ko04972	Pancreatic secretion	4/751	111/7206	0.0120599835537
ko00561	Glycerolipid metabolism	1/751	63/7206	0.0125165198488
ko04670	Leukocyte transendothelial migration	7/751	151/7206	0.0149371440569
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	2/751	79/7206	0.0150680530409
ko04512	ECM-receptor interaction	2/751	79/7206	0.0150680530409
ko04721	Synaptic vesicle cycle	2/751	80/7206	0.0152347881168
ko04976	Bile secretion	2/751	80/7206	0.0152347881168
ko05167	Kaposi's sarcoma-associated herpesvirus infection	10/751	191/7206	0.0157229038626
ko04066	HIF-1 signaling pathway	5/751	123/7206	0.0164142249059
ko05016	Huntington's disease	12/751	215/7206	0.0167613720504
ko04658	Th1 and Th2 cell differentiation	3/751	96/7206	0.0168550603262
ko05200	Pathways in cancer	36/751	492/7206	0.0177374390355
ko01212	Fatty acid metabolism	1/751	60/7206	0.0183351526137
ko04071	Sphingolipid signaling pathway	8/751	162/7206	0.0185186665441
ko04140	Autophagy - animal	8/751	164/7206	0.0189230138157
ko04622	RIG-I-like receptor signaling pathway	1/751	62/7206	0.0189848366743
ko04933	AGE-RAGE signaling pathway in diabetic complications	6/751	135/7206	0.0215934493499
ko04923	Regulation of lipolysis in adipocytes	2/751	77/7206	0.0221216509764
ko04925	Aldosterone synthesis and secretion	4/751	105/7206	0.0229667308495
ko04659	Th17 cell differentiation	4/751	106/7206	0.0232903275167
ko05321	Inflammatory bowel disease (IBD)	1/751	56/7206	0.026804199824
ko01200	Carbon metabolism	6/751	128/7206	0.0281702307106
ko04540	Gap junction	6/751	128/7206	0.0281702307106
ko05164	Influenza A	9/751	167/7206	0.0288637374607
ko00564	Glycerophospholipid metabolism	4/751	99/7206	0.0311258793512
ko04115	p53 signaling pathway	14/751	74/7206	0.032233442716
ko04662	B cell receptor signaling pathway	3/751	88/7206	0.032651667104
ko00590	Arachidonic acid metabolism	1/751	52/7206	0.0391078270028
ko04012	ErbB signaling pathway	5/751	109/7206	0.04014464223
ko04930	Type II diabetes mellitus	1/751	54/7206	0.0402721316349
ko04931	Insulin resistance	7/751	137/7206	0.0463081511062
ko05162	Measles	6/751	120/7206	0.0495291096235
ko00670	One carbon pool by folate	5/751	20/7206	0.0499953794851