ko pathway ratio_in_study ratio_in_pop p_value ko00190 Oxidative phosphorylation 44/186 127/7206 3.32273595278e-39 ko05012 Parkinson's disease 43/186 155/7206 1.29083009735e-33 ko05016 Huntington's disease 45/186 215/7206 2.21815138024e-29 ko05010 Alzheimer's disease 43/186 202/7206 2.25427765602e-28 ko04932 Non-alcoholic fatty liver disease (NAFLD) 35/186 182/7206 1.59355155753e-21 ko04260 Cardiac muscle contraction 21/186 98/7206 3.25058479822e-14 ko01200 Carbon metabolism 22/186 128/7206 9.27865434562e-13 ko04723 Retrograde endocannabinoid signaling 23/186 175/7206 8.51461787807e-11 ko05410 Hypertrophic cardiomyopathy (HCM) 17/186 100/7206 4.93577017139e-10 ko00020 Citrate cycle (TCA cycle) 10/186 35/7206 1.08114758339e-08 ko00010 Glycolysis / Gluconeogenesis 12/186 74/7206 3.32715895795e-07 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 12/186 79/7206 6.93663824149e-07 ko05414 Dilated cardiomyopathy 14/186 112/7206 9.38022080496e-07 ko00710 Carbon fixation in photosynthetic organisms 7/186 27/7206 3.91010751431e-06 ko01230 Biosynthesis of amino acids 11/186 85/7206 1.0188202214e-05 ko04921 Oxytocin signaling pathway 16/186 209/7206 9.14158582924e-05 ko00620 Pyruvate metabolism 7/186 46/7206 0.000155652564803 ko00680 Methane metabolism 6/186 34/7206 0.000200907707874 ko04261 Adrenergic signaling in cardiomyocytes 15/186 205/7206 0.000250808082672 ko04371 Apelin signaling pathway 12/186 177/7206 0.00201853837794 ko00220 Arginine biosynthesis 4/186 24/7206 0.00304664106891 ko00030 Pentose phosphate pathway 4/186 32/7206 0.00878313134719 ko04015 Rap1 signaling pathway 1/186 278/7206 0.0105812805088 ko04014 Ras signaling pathway 1/186 279/7206 0.0106365661082 ko00640 Propanoate metabolism 4/186 34/7206 0.0108841402452 ko04022 cGMP-PKG signaling pathway 12/186 216/7206 0.0131175405027 ko05416 Viral myocarditis 5/186 55/7206 0.013307038967 ko01210 2-Oxocarboxylic acid metabolism 3/186 20/7206 0.0139592681272 ko00250 Alanine, aspartate and glutamate metabolism 4/186 38/7206 0.0159985995321 ko04922 Glucagon signaling pathway 8/186 128/7206 0.0174343580314 ko00051 Fructose and mannose metabolism 4/186 42/7206 0.0224103254587 ko04213 Longevity regulating pathway - multiple species 6/186 86/7206 0.0233318482968 ko04020 Calcium signaling pathway 13/186 265/7206 0.0264636505949 ko04010 MAPK signaling pathway 15/186 321/7206 0.0277649253734 ko04510 Focal adhesion 12/186 240/7206 0.0340044629553 ko04152 AMPK signaling pathway 9/186 161/7206 0.0373725896741 ko04964 Proximal tubule bicarbonate reclamation 3/186 29/7206 0.0378024203952 ko04910 Insulin signaling pathway 9/186 172/7206 0.0441931321889