ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	82/969	152/7206	3.7262633453e-33
ko04080	Neuroactive ligand-receptor interaction	148/969	423/7206	1.35919745624e-31
ko05032	Morphine addiction	63/969	110/7206	1.22737660194e-27
ko04713	Circadian entrainment	69/969	136/7206	6.78397601237e-26
ko05033	Nicotine addiction	42/969	56/7206	1.01120068473e-25
ko04728	Dopaminergic synapse	78/969	185/7206	1.39153758954e-22
ko04727	GABAergic synapse	57/969	110/7206	3.71385616343e-22
ko04725	Cholinergic synapse	67/969	160/7206	2.44776584872e-19
ko04723	Retrograde endocannabinoid signaling	70/969	175/7206	7.87088586162e-19
ko04024	cAMP signaling pathway	91/969	279/7206	3.42811176069e-17
ko04721	Synaptic vesicle cycle	42/969	80/7206	6.5963838178e-17
ko04744	Phototransduction	25/969	36/7206	1.70490805133e-14
ko04921	Oxytocin signaling pathway	68/969	209/7206	5.18450090425e-13
ko04911	Insulin secretion	46/969	117/7206	1.85664723823e-12
ko04020	Calcium signaling pathway	78/969	265/7206	4.76342608171e-12
ko04726	Serotonergic synapse	50/969	137/7206	5.48388321505e-12
ko04720	Long-term potentiation	39/969	99/7206	8.64607107582e-11
ko05031	Amphetamine addiction	37/969	91/7206	8.91858802362e-11
ko04261	Adrenergic signaling in cardiomyocytes	62/969	205/7206	2.18876775121e-10
ko04742	Taste transduction	28/969	61/7206	6.28694552633e-10
ko03040	Spliceosome	1/969	145/7206	2.31426086282e-08
ko04925	Aldosterone synthesis and secretion	35/969	105/7206	1.24039981371e-07
ko04360	Axon guidance	61/969	233/7206	1.34210703246e-07
ko05030	Cocaine addiction	27/969	73/7206	3.24314811656e-07
ko04970	Salivary secretion	32/969	95/7206	3.28181006235e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/969	74/7206	4.46318352574e-07
ko04740	Olfactory transduction	28/969	80/7206	7.362747228e-07
ko05203	Viral carcinogenesis	13/969	277/7206	1.49669707536e-06
ko04971	Gastric acid secretion	31/969	98/7206	2.97589032308e-06
ko04010	MAPK signaling pathway	73/969	321/7206	3.32085852673e-06
ko04514	Cell adhesion molecules (CAMs)	37/969	130/7206	5.70673763983e-06
ko03013	RNA transport	5/969	166/7206	8.03935957173e-06
ko04022	cGMP-PKG signaling pathway	53/969	216/7206	9.76740276038e-06
ko04072	Phospholipase D signaling pathway	49/969	197/7206	1.10220621251e-05
ko04621	NOD-like receptor signaling pathway	5/969	157/7206	1.59661822313e-05
ko05322	Systemic lupus erythematosus	5/969	151/7206	3.28079105305e-05
ko04745	Phototransduction - fly	15/969	38/7206	5.74152427857e-05
ko04070	Phosphatidylinositol signaling system	31/969	112/7206	6.10159221909e-05
ko04730	Long-term depression	24/969	78/7206	6.49594335774e-05
ko04972	Pancreatic secretion	30/969	111/7206	0.000115808532566
ko05164	Influenza A	7/969	167/7206	0.000120848156137
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/969	79/7206	0.000202249672877
ko04014	Ras signaling pathway	59/969	279/7206	0.000309438971126
ko03008	Ribosome biogenesis in eukaryotes	1/969	79/7206	0.000331253128511
ko04060	Cytokine-cytokine receptor interaction	10/969	191/7206	0.000334171252678
ko04260	Cardiac muscle contraction	26/969	98/7206	0.000476754374095
ko05168	Herpes simplex infection	10/969	182/7206	0.000603928824549
ko04141	Protein processing in endoplasmic reticulum	10/969	184/7206	0.000609407655843
ko04110	Cell cycle	7/969	145/7206	0.00120228121009
ko05169	Epstein-Barr virus infection	13/969	206/7206	0.00124854266233
ko04064	NF-kappa B signaling pathway	3/969	96/7206	0.00127127550394
ko05161	Hepatitis B	10/969	173/7206	0.0014806004324
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/969	59/7206	0.0016435728999
ko04915	Estrogen signaling pathway	31/969	131/7206	0.00166031972157
ko04750	Inflammatory mediator regulation of TRP channels	29/969	122/7206	0.00181468985399
ko04930	Type II diabetes mellitus	16/969	54/7206	0.00183276968352
ko04612	Antigen processing and presentation	2/969	77/7206	0.00212234844015
ko04924	Renin secretion	22/969	86/7206	0.00217871092657
ko04540	Gap junction	30/969	128/7206	0.00230783611555
ko04640	Hematopoietic cell lineage	1/969	64/7206	0.00246936117209
ko05140	Leishmaniasis	2/969	75/7206	0.00316957232512
ko05205	Proteoglycans in cancer	21/969	271/7206	0.00359880746432
ko04711	Circadian rhythm - fly	6/969	13/7206	0.00429997026725
ko05414	Dilated cardiomyopathy	26/969	112/7206	0.00469322491748
ko04966	Collecting duct acid secretion	9/969	26/7206	0.00507638350084
ko04371	Apelin signaling pathway	37/969	177/7206	0.00508030283017
ko00480	Glutathione metabolism	1/969	55/7206	0.00508499186843
ko04710	Circadian rhythm	13/969	43/7206	0.00519226108739
ko04120	Ubiquitin mediated proteolysis	8/969	138/7206	0.00529621602377
ko04923	Regulation of lipolysis in adipocytes	19/969	77/7206	0.00665577139268
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/969	14/7206	0.00667905195013
ko00562	Inositol phosphate metabolism	21/969	89/7206	0.00760610812169
ko04722	Neurotrophin signaling pathway	33/969	160/7206	0.00976740985382
ko04973	Carbohydrate digestion and absorption	12/969	42/7206	0.00981928753802
ko00240	Pyrimidine metabolism	6/969	110/7206	0.0105785751304
ko04146	Peroxisome	4/969	89/7206	0.0112011027278
ko00330	Arginine and proline metabolism	2/969	61/7206	0.0135251567221
ko00620	Pyruvate metabolism	1/969	46/7206	0.0165484336533
ko03420	Nucleotide excision repair	1/969	46/7206	0.0165484336533
ko04114	Oocyte meiosis	28/969	139/7206	0.0236757959624
ko05110	Vibrio cholerae infection	15/969	63/7206	0.0240100609507
ko03022	Basal transcription factors	1/969	44/7206	0.0245924660756
ko00071	Fatty acid degradation	1/969	45/7206	0.0252554212249
ko04626	Plant-pathogen interaction	6/969	18/7206	0.0257296583079
ko04062	Chemokine signaling pathway	38/969	201/7206	0.027116661336
ko05321	Inflammatory bowel disease (IBD)	2/969	56/7206	0.0283010944341
ko05162	Measles	8/969	120/7206	0.0296437608334
ko04976	Bile secretion	18/969	80/7206	0.0300291795986
ko04015	Rap1 signaling pathway	50/969	278/7206	0.0308706428608
ko04510	Focal adhesion	21/969	240/7206	0.0335861394125
ko04071	Sphingolipid signaling pathway	31/969	162/7206	0.0360074865247
ko00980	Metabolism of xenobiotics by cytochrome P450	1/969	40/7206	0.0360146864714
ko00140	Steroid hormone biosynthesis	1/969	41/7206	0.0362981601525
ko05410	Hypertrophic cardiomyopathy (HCM)	21/969	100/7206	0.0370615388837
ko04657	IL-17 signaling pathway	5/969	87/7206	0.0379345063862
ko05133	Pertussis	5/969	87/7206	0.0379345063862
ko04115	p53 signaling pathway	4/969	74/7206	0.039227313481
ko00280	Valine, leucine and isoleucine degradation	2/969	54/7206	0.0417361658551
ko04217	Necroptosis	15/969	178/7206	0.0452798647488
ko04964	Proximal tubule bicarbonate reclamation	8/969	29/7206	0.0482288265305
ko05215	Prostate cancer	8/969	111/7206	0.0499326871345