ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03010	Ribosome	115/726	129/7206	2.35237215242e-101
ko03050	Proteasome	37/726	54/7206	5.04272280859e-25
ko04080	Neuroactive ligand-receptor interaction	1/726	423/7206	7.40411845019e-19
ko03013	RNA transport	58/726	166/7206	1.53651606508e-18
ko03040	Spliceosome	49/726	145/7206	3.64129238522e-15
ko03008	Ribosome biogenesis in eukaryotes	30/726	79/7206	3.20159843457e-11
ko03020	RNA polymerase	16/726	29/7206	1.85590879487e-09
ko04020	Calcium signaling pathway	4/726	265/7206	2.99189358311e-08
ko04060	Cytokine-cytokine receptor interaction	1/726	191/7206	5.79991375362e-08
ko00970	Aminoacyl-tRNA biosynthesis	18/726	44/7206	7.66382338268e-08
ko05169	Epstein-Barr virus infection	46/726	206/7206	1.92730968437e-07
ko03015	mRNA surveillance pathway	27/726	93/7206	2.30487392435e-07
ko03030	DNA replication	15/726	38/7206	1.63310732997e-06
ko03060	Protein export	11/726	23/7206	4.37418278806e-06
ko04024	cAMP signaling pathway	8/726	279/7206	5.7994431258e-06
ko04068	FoxO signaling pathway	2/726	167/7206	5.87049786532e-06
ko00240	Pyrimidine metabolism	27/726	110/7206	8.21573891864e-06
ko04010	MAPK signaling pathway	12/726	321/7206	2.48484781121e-05
ko04724	Glutamatergic synapse	2/726	152/7206	2.81417997711e-05
ko04144	Endocytosis	14/726	342/7206	4.43064046667e-05
ko04022	cGMP-PKG signaling pathway	6/726	216/7206	4.93919469316e-05
ko04921	Oxytocin signaling pathway	6/726	209/7206	9.73972584401e-05
ko03420	Nucleotide excision repair	14/726	46/7206	0.000108934170549
ko04070	Phosphatidylinositol signaling system	1/726	112/7206	0.000181916132734
ko04630	Jak-STAT signaling pathway	2/726	132/7206	0.000189628643847
ko05034	Alcoholism	9/726	238/7206	0.000403099222721
ko04725	Cholinergic synapse	4/726	160/7206	0.000440967094575
ko04723	Retrograde endocannabinoid signaling	5/726	175/7206	0.000490982245201
ko04015	Rap1 signaling pathway	12/726	278/7206	0.000501145217388
ko04014	Ras signaling pathway	12/726	279/7206	0.000504234681868
ko04931	Insulin resistance	3/726	137/7206	0.000508251428764
ko04726	Serotonergic synapse	3/726	137/7206	0.000508251428764
ko05010	Alzheimer's disease	7/726	202/7206	0.000537129424829
ko03018	RNA degradation	19/726	84/7206	0.000670741113563
ko04380	Osteoclast differentiation	3/726	134/7206	0.000727334133152
ko04713	Circadian entrainment	3/726	136/7206	0.000750799719433
ko04062	Chemokine signaling pathway	7/726	201/7206	0.00075403107647
ko04974	Protein digestion and absorption	1/726	96/7206	0.000873214364129
ko04650	Natural killer cell mediated cytotoxicity	1/726	97/7206	0.000907124008088
ko04727	GABAergic synapse	2/726	110/7206	0.0011999891423
ko05032	Morphine addiction	2/726	110/7206	0.0011999891423
ko04922	Glucagon signaling pathway	3/726	128/7206	0.00153378700976
ko04141	Protein processing in endoplasmic reticulum	32/726	184/7206	0.00178083271768
ko00562	Inositol phosphate metabolism	1/726	89/7206	0.00197309855856
ko00230	Purine metabolism	33/726	194/7206	0.00231450196017
ko04072	Phospholipase D signaling pathway	8/726	197/7206	0.0025107743277
ko05231	Choline metabolism in cancer	4/726	134/7206	0.0033277397038
ko04933	AGE-RAGE signaling pathway in diabetic complications	4/726	135/7206	0.00338920252363
ko03022	Basal transcription factors	11/726	44/7206	0.00344786190673
ko04971	Gastric acid secretion	2/726	98/7206	0.00361565276754
ko00564	Glycerophospholipid metabolism	2/726	99/7206	0.00365441797013
ko05410	Hypertrophic cardiomyopathy (HCM)	2/726	100/7206	0.00373231446114
ko04620	Toll-like receptor signaling pathway	2/726	100/7206	0.00373231446114
ko04612	Antigen processing and presentation	16/726	77/7206	0.00393552804052
ko04730	Long-term depression	1/726	78/7206	0.00399683841149
ko04610	Complement and coagulation cascades	1/726	79/7206	0.00403606066578
ko04740	Olfactory transduction	1/726	80/7206	0.00412791799535
ko04261	Adrenergic signaling in cardiomyocytes	9/726	205/7206	0.00437343860017
ko03430	Mismatch repair	7/726	22/7206	0.00450902258185
ko05142	Chagas disease (American trypanosomiasis)	4/726	130/7206	0.00464970691606
ko04919	Thyroid hormone signaling pathway	5/726	143/7206	0.00474749495674
ko04970	Salivary secretion	2/726	95/7206	0.00526034041684
ko04510	Focal adhesion	12/726	240/7206	0.00607455710981
ko04728	Dopaminergic synapse	8/726	185/7206	0.00608022886573
ko05414	Dilated cardiomyopathy	3/726	112/7206	0.00623369666737
ko04370	VEGF signaling pathway	1/726	77/7206	0.0062791495784
ko04923	Regulation of lipolysis in adipocytes	1/726	77/7206	0.0062791495784
ko04623	Cytosolic DNA-sensing pathway	10/726	41/7206	0.00628048997005
ko04270	Vascular smooth muscle contraction	6/726	154/7206	0.00648011762251
ko04916	Melanogenesis	5/726	142/7206	0.00673651604571
ko05120	Epithelial cell signaling in Helicobacter pylori infection	2/726	92/7206	0.00771989347315
ko04925	Aldosterone synthesis and secretion	3/726	105/7206	0.00838436126634
ko04912	GnRH signaling pathway	4/726	122/7206	0.00900160904808
ko04750	Inflammatory mediator regulation of TRP channels	4/726	122/7206	0.00900160904808
ko04360	Axon guidance	12/726	233/7206	0.0103844922999
ko05220	Chronic myeloid leukemia	2/726	85/7206	0.0106606428573
ko04924	Renin secretion	2/726	86/7206	0.0106925349095
ko04371	Apelin signaling pathway	8/726	177/7206	0.010804324636
ko04917	Prolactin signaling pathway	2/726	87/7206	0.010826721184
ko03410	Base excision repair	9/726	38/7206	0.0113903813754
ko00670	One carbon pool by folate	6/726	20/7206	0.0115402344622
ko04514	Cell adhesion molecules (CAMs)	5/726	130/7206	0.0121677210735
ko04911	Insulin secretion	4/726	117/7206	0.0122911448851
ko04810	Regulation of actin cytoskeleton	15/726	264/7206	0.012356809769
ko05223	Non-small cell lung cancer	1/726	66/7206	0.0126607156955
ko03320	PPAR signaling pathway	1/726	69/7206	0.0134985689664
ko05212	Pancreatic cancer	2/726	83/7206	0.0154750458881
ko03460	Fanconi anemia pathway	11/726	51/7206	0.0155462325187
ko00190	Oxidative phosphorylation	5/726	127/7206	0.0165665920679
ko01200	Carbon metabolism	5/726	128/7206	0.0167033759728
ko04720	Long-term potentiation	3/726	99/7206	0.0169299335992
ko05146	Amoebiasis	3/726	99/7206	0.0169299335992
ko05213	Endometrial cancer	1/726	62/7206	0.0185344010664
ko04913	Ovarian steroidogenesis	1/726	63/7206	0.0187261448289
ko00561	Glycerolipid metabolism	1/726	63/7206	0.0187261448289
ko04640	Hematopoietic cell lineage	1/726	64/7206	0.0191292731711
ko04151	PI3K-Akt signaling pathway	26/726	390/7206	0.019399436807
ko05322	Systemic lupus erythematosus	7/726	151/7206	0.0200315005788
ko05160	Hepatitis C	7/726	153/7206	0.0201410293204
ko05167	Kaposi's sarcoma-associated herpesvirus infection	10/726	191/7206	0.0204427549669
ko04664	Fc epsilon RI signaling pathway	2/726	77/7206	0.0216486924877
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	2/726	79/7206	0.0220582952037
ko04512	ECM-receptor interaction	2/726	79/7206	0.0220582952037
ko05214	Glioma	2/726	79/7206	0.0220582952037
ko05200	Pathways in cancer	35/726	492/7206	0.0241252761389
ko04611	Platelet activation	8/726	163/7206	0.0245018841839
ko04110	Cell cycle	23/726	145/7206	0.0251167464864
ko04712	Circadian rhythm - plant	3/726	7/7206	0.0261432523669
ko01212	Fatty acid metabolism	1/726	60/7206	0.0279553453952
ko03070	Bacterial secretion system	2/726	3/7206	0.0283758819662
ko04742	Taste transduction	1/726	61/7206	0.0288333686065
ko04910	Insulin signaling pathway	9/726	172/7206	0.0290892655707
ko05140	Leishmaniasis	2/726	75/7206	0.0313474190751
ko04621	NOD-like receptor signaling pathway	8/726	157/7206	0.0319313794487
ko04146	Peroxisome	3/726	89/7206	0.0319636011098
ko04659	Th17 cell differentiation	4/726	106/7206	0.0324242525143
ko05031	Amphetamine addiction	3/726	91/7206	0.032930516749
ko04915	Estrogen signaling pathway	6/726	131/7206	0.0385174179616
ko00280	Valine, leucine and isoleucine degradation	1/726	54/7206	0.0394981018982
ko04260	Cardiac muscle contraction	4/726	98/7206	0.0427155988192
ko04217	Necroptosis	10/726	178/7206	0.0434728081749
ko05218	Melanoma	3/726	85/7206	0.0442716890703
ko04657	IL-17 signaling pathway	3/726	87/7206	0.0456569629227
ko04111	Cell cycle - yeast	15/726	90/7206	0.0498352876612
ko04660	T cell receptor signaling pathway	6/726	124/7206	0.0498895385171