ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 32/270 191/7206 4.54554267482e-13 ko04380 Osteoclast differentiation 20/270 134/7206 1.01646651437e-07 ko04217 Necroptosis 21/270 178/7206 2.67732633443e-06 ko05164 Influenza A 20/270 167/7206 3.69572897703e-06 ko04621 NOD-like receptor signaling pathway 19/270 157/7206 5.57411192961e-06 ko04650 Natural killer cell mediated cytotoxicity 14/270 97/7206 1.31500577334e-05 ko05162 Measles 15/270 120/7206 3.7552973484e-05 ko05160 Hepatitis C 17/270 153/7206 5.3471867268e-05 ko04064 NF-kappa B signaling pathway 13/270 96/7206 5.34964868525e-05 ko05140 Leishmaniasis 11/270 75/7206 9.67317763031e-05 ko04666 Fc gamma R-mediated phagocytosis 14/270 122/7206 0.000173638688301 ko05152 Tuberculosis 18/270 187/7206 0.000209704460083 ko04658 Th1 and Th2 cell differentiation 12/270 96/7206 0.000225571996425 ko05145 Toxoplasmosis 14/270 126/7206 0.000244703626975 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/270 191/7206 0.000273110042011 ko04630 Jak-STAT signaling pathway 14/270 132/7206 0.000397650361821 ko04062 Chemokine signaling pathway 18/270 201/7206 0.000509443855289 ko04659 Th17 cell differentiation 12/270 106/7206 0.000569721154641 ko00590 Arachidonic acid metabolism 8/270 52/7206 0.000628294422066 ko04660 T cell receptor signaling pathway 13/270 124/7206 0.000713069519826 ko00140 Steroid hormone biosynthesis 7/270 41/7206 0.00072199426693 ko05321 Inflammatory bowel disease (IBD) 8/270 56/7206 0.00104201512027 ko05168 Herpes simplex infection 16/270 182/7206 0.00126232244645 ko04668 TNF signaling pathway 12/270 120/7206 0.00171459697607 ko00051 Fructose and mannose metabolism 6/270 42/7206 0.00441140444625 ko04933 AGE-RAGE signaling pathway in diabetic complications 12/270 135/7206 0.00457782941609 ko05340 Primary immunodeficiency 5/270 30/7206 0.00469756826607 ko04611 Platelet activation 14/270 163/7206 0.00495212597451 ko04662 B cell receptor signaling pathway 9/270 88/7206 0.00546118190662 ko04750 Inflammatory mediator regulation of TRP channels 11/270 122/7206 0.00586578715502 ko04664 Fc epsilon RI signaling pathway 8/270 77/7206 0.00785556425166 ko04610 Complement and coagulation cascades 8/270 79/7206 0.00913618424295 ko04390 Hippo signaling pathway 1/270 188/7206 0.0104222461183 ko05230 Central carbon metabolism in cancer 8/270 81/7206 0.0105666230202 ko04672 Intestinal immune network for IgA production 5/270 37/7206 0.011616838216 ko04670 Leukocyte transendothelial migration 12/270 151/7206 0.0138846743867 ko04657 IL-17 signaling pathway 8/270 87/7206 0.0158548434888 ko05133 Pertussis 8/270 87/7206 0.0158548434888 ko05231 Choline metabolism in cancer 11/270 134/7206 0.0173035755239 ko04612 Antigen processing and presentation 7/270 77/7206 0.0247212188521 ko04210 Apoptosis 13/270 180/7206 0.0251602131452 ko04622 RIG-I-like receptor signaling pathway 6/270 62/7206 0.0278370766167 ko05132 Salmonella infection 8/270 98/7206 0.0301210992546 ko05012 Parkinson's disease 1/270 155/7206 0.0313357150284 ko05034 Alcoholism 3/270 238/7206 0.0359974059562 ko00120 Primary bile acid biosynthesis 3/270 20/7206 0.0370028405261 ko04931 Insulin resistance 10/270 137/7206 0.0376508993631 ko05418 Fluid shear stress and atherosclerosis 12/270 173/7206 0.0386928491029 ko05161 Hepatitis B 12/270 173/7206 0.0386928491029 ko03320 PPAR signaling pathway 6/270 69/7206 0.043818697293 ko04917 Prolactin signaling pathway 7/270 87/7206 0.0439888650874 ko05150 Staphylococcus aureus infection 4/270 36/7206 0.044344954124 ko04912 GnRH signaling pathway 9/270 122/7206 0.0482019429257 ko00982 Drug metabolism - cytochrome P450 4/270 37/7206 0.0483119984767 ko05323 Rheumatoid arthritis 7/270 89/7206 0.048750376196