ko pathway ratio_in_study ratio_in_pop p_value ko05033 Nicotine addiction 21/412 56/7206 1.01643000433e-12 ko05032 Morphine addiction 27/412 110/7206 5.45423437111e-11 ko04360 Axon guidance 41/412 233/7206 5.55129943423e-11 ko04727 GABAergic synapse 26/412 110/7206 3.08018047116e-10 ko04724 Glutamatergic synapse 30/412 152/7206 1.43749488128e-09 ko04723 Retrograde endocannabinoid signaling 32/412 175/7206 2.98919110419e-09 ko04721 Synaptic vesicle cycle 19/412 80/7206 7.34445862266e-08 ko04728 Dopaminergic synapse 29/412 185/7206 5.43122685206e-07 ko04514 Cell adhesion molecules (CAMs) 22/412 130/7206 3.63132441978e-06 ko04713 Circadian entrainment 21/412 136/7206 2.59683312703e-05 ko04725 Cholinergic synapse 23/412 160/7206 3.51630709714e-05 ko05203 Viral carcinogenesis 3/412 277/7206 0.000104007745386 ko04726 Serotonergic synapse 19/412 137/7206 0.000269919792058 ko04024 cAMP signaling pathway 31/412 279/7206 0.000315418743438 ko04080 Neuroactive ligand-receptor interaction 41/412 423/7206 0.000737267306205 ko00604 Glycosphingolipid biosynthesis - ganglio series 5/412 14/7206 0.000776166612495 ko05014 Amyotrophic lateral sclerosis (ALS) 12/412 74/7206 0.000898984930091 ko03013 RNA transport 1/412 166/7206 0.00104511328399 ko04744 Phototransduction 7/412 36/7206 0.00373512680326 ko04140 Autophagy - animal 2/412 164/7206 0.00605560485298 ko05030 Cocaine addiction 10/412 73/7206 0.00817501514793 ko04141 Protein processing in endoplasmic reticulum 3/412 184/7206 0.00958708851948 ko05169 Epstein-Barr virus infection 4/412 206/7206 0.0138522875534 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 10/412 79/7206 0.0139999226143 ko03040 Spliceosome 2/412 145/7206 0.0173650980042 ko04391 Hippo signaling pathway - fly 11/412 90/7206 0.0179619329503 ko04961 Endocrine and other factor-regulated calcium reabsorption 8/412 59/7206 0.0182191846197 ko04261 Adrenergic signaling in cardiomyocytes 20/412 205/7206 0.0203565654685 ko04911 Insulin secretion 13/412 117/7206 0.0236732802351 ko04120 Ubiquitin mediated proteolysis 2/412 138/7206 0.024491248659 ko05016 Huntington's disease 5/412 215/7206 0.0247181565297 ko04060 Cytokine-cytokine receptor interaction 4/412 191/7206 0.0256769974275 ko04010 MAPK signaling pathway 28/412 321/7206 0.0257494240033 ko05164 Influenza A 3/412 167/7206 0.0262292037937 ko04932 Non-alcoholic fatty liver disease (NAFLD) 4/412 182/7206 0.0345813986223 ko04630 Jak-STAT signaling pathway 2/412 132/7206 0.03472440078 ko05414 Dilated cardiomyopathy 12/412 112/7206 0.0360032568902 ko05205 Proteoglycans in cancer 8/412 271/7206 0.0447405570449 ko00564 Glycerophospholipid metabolism 1/412 99/7206 0.0452414453933 ko05161 Hepatitis B 4/412 173/7206 0.0465812486896 ko04921 Oxytocin signaling pathway 19/412 209/7206 0.0470187046314 ko04217 Necroptosis 4/412 178/7206 0.0474171617485 ko05162 Measles 2/412 120/7206 0.0477043829002 ko04668 TNF signaling pathway 2/412 120/7206 0.0477043829002