ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	46/500	152/7206	1.53279233121e-18
ko04721	Synaptic vesicle cycle	28/500	80/7206	1.67799219985e-13
ko05032	Morphine addiction	33/500	110/7206	1.72389961663e-13
ko05033	Nicotine addiction	23/500	56/7206	5.0079686343e-13
ko04727	GABAergic synapse	31/500	110/7206	6.01996162787e-12
ko04728	Dopaminergic synapse	40/500	185/7206	5.01410903622e-11
ko04723	Retrograde endocannabinoid signaling	35/500	175/7206	7.56996550162e-09
ko04725	Cholinergic synapse	32/500	160/7206	3.39406554213e-08
ko04713	Circadian entrainment	29/500	136/7206	3.44312658592e-08
ko04080	Neuroactive ligand-receptor interaction	59/500	423/7206	1.66156288116e-07
ko04024	cAMP signaling pathway	42/500	279/7206	1.48572480322e-06
ko04911	Insulin secretion	23/500	117/7206	4.05680439661e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	17/500	74/7206	8.57965937678e-06
ko04726	Serotonergic synapse	24/500	137/7206	1.98023818167e-05
ko04514	Cell adhesion molecules (CAMs)	23/500	130/7206	2.49805061338e-05
ko05030	Cocaine addiction	16/500	73/7206	2.95518632774e-05
ko04360	Axon guidance	34/500	233/7206	3.16266003981e-05
ko04744	Phototransduction	10/500	36/7206	0.000115903351605
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/500	14/7206	0.000201084741719
ko04261	Adrenergic signaling in cardiomyocytes	29/500	205/7206	0.000213961045327
ko03013	RNA transport	2/500	166/7206	0.000970395635506
ko05031	Amphetamine addiction	15/500	91/7206	0.00135755879003
ko05034	Alcoholism	29/500	238/7206	0.00260080485898
ko04742	Taste transduction	11/500	61/7206	0.00280793522176
ko04060	Cytokine-cytokine receptor interaction	4/500	191/7206	0.00370014422771
ko03040	Spliceosome	2/500	145/7206	0.00423283889391
ko04611	Platelet activation	3/500	163/7206	0.00474804931996
ko05203	Viral carcinogenesis	8/500	277/7206	0.00510371952227
ko04120	Ubiquitin mediated proteolysis	2/500	138/7206	0.00593658134027
ko05168	Herpes simplex infection	4/500	182/7206	0.00714675702595
ko04966	Collecting duct acid secretion	6/500	26/7206	0.00754729792498
ko04260	Cardiac muscle contraction	14/500	98/7206	0.00817671496204
ko04145	Phagosome	20/500	162/7206	0.0112248363434
ko04010	MAPK signaling pathway	34/500	321/7206	0.0128534925587
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/500	8/7206	0.014290541845
ko00564	Glycerophospholipid metabolism	1/500	99/7206	0.0145664042594
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/500	15/7206	0.0169041855094
ko05162	Measles	2/500	120/7206	0.0169259577544
ko04141	Protein processing in endoplasmic reticulum	5/500	184/7206	0.0179943571268
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/500	59/7206	0.0194251362888
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	11/500	79/7206	0.0230366200704
ko04973	Carbohydrate digestion and absorption	7/500	42/7206	0.0240201933417
ko05205	Proteoglycans in cancer	10/500	271/7206	0.0280961583268
ko04014	Ras signaling pathway	29/500	279/7206	0.0294229199887
ko03018	RNA degradation	1/500	84/7206	0.0294370294483
ko05133	Pertussis	1/500	87/7206	0.0303445191147
ko05167	Kaposi's sarcoma-associated herpesvirus infection	21/500	191/7206	0.0303660418941
ko05322	Systemic lupus erythematosus	4/500	151/7206	0.033962399167
ko01200	Carbon metabolism	3/500	128/7206	0.0343056145521
ko00240	Pyrimidine metabolism	2/500	110/7206	0.0344355926387
ko05120	Epithelial cell signaling in Helicobacter pylori infection	12/500	92/7206	0.0347197536974
ko05146	Amoebiasis	2/500	99/7206	0.0466004355785
ko04964	Proximal tubule bicarbonate reclamation	5/500	29/7206	0.0468887626719