ko pathway ratio_in_study ratio_in_pop p_value ko04610 Complement and coagulation cascades 21/498 79/7206 4.80235262445e-08 ko04060 Cytokine-cytokine receptor interaction 34/498 191/7206 2.26610863071e-07 ko04710 Circadian rhythm 13/498 43/7206 3.7490696443e-06 ko04070 Phosphatidylinositol signaling system 22/498 112/7206 6.24177012366e-06 ko04380 Osteoclast differentiation 23/498 134/7206 3.86947052852e-05 ko04072 Phospholipase D signaling pathway 29/498 197/7206 8.6747800144e-05 ko03013 RNA transport 1/498 166/7206 0.000144121217733 ko04650 Natural killer cell mediated cytotoxicity 17/498 97/7206 0.000302820582324 ko05034 Alcoholism 4/498 238/7206 0.000360496744438 ko05140 Leishmaniasis 14/498 75/7206 0.00052599255975 ko05150 Staphylococcus aureus infection 9/498 36/7206 0.000583680409781 ko04672 Intestinal immune network for IgA production 9/498 37/7206 0.000724928108717 ko03010 Ribosome 1/498 129/7206 0.00225418645691 ko04611 Platelet activation 22/498 163/7206 0.00246269125861 ko04270 Vascular smooth muscle contraction 21/498 154/7206 0.00314799488413 ko00562 Inositol phosphate metabolism 14/498 89/7206 0.00457530563037 ko04933 AGE-RAGE signaling pathway in diabetic complications 18/498 135/7206 0.00581623789933 ko04659 Th17 cell differentiation 15/498 106/7206 0.00640728646714 ko04022 cGMP-PKG signaling pathway 25/498 216/7206 0.00935411488449 ko04711 Circadian rhythm - fly 4/498 13/7206 0.0097528111083 ko00120 Primary bile acid biosynthesis 5/498 20/7206 0.0100461205243 ko04666 Fc gamma R-mediated phagocytosis 16/498 122/7206 0.0110179465878 ko04640 Hematopoietic cell lineage 10/498 64/7206 0.0116984649637 ko01200 Carbon metabolism 2/498 128/7206 0.0122240350672 ko04137 Mitophagy - animal 12/498 82/7206 0.0128709441132 ko04630 Jak-STAT signaling pathway 17/498 132/7206 0.0134610745041 ko05321 Inflammatory bowel disease (IBD) 9/498 56/7206 0.0137292262439 ko05231 Choline metabolism in cancer 17/498 134/7206 0.0144015459272 ko05340 Primary immunodeficiency 6/498 30/7206 0.0151066757215 ko04014 Ras signaling pathway 30/498 279/7206 0.0152816528946 ko04621 NOD-like receptor signaling pathway 19/498 157/7206 0.0157225861593 ko04110 Cell cycle 3/498 145/7206 0.0187300031723 ko04662 B cell receptor signaling pathway 12/498 88/7206 0.0190721799813 ko04391 Hippo signaling pathway - fly 1/498 90/7206 0.0203338313226 ko04658 Th1 and Th2 cell differentiation 13/498 96/7206 0.022430169261 ko04020 Calcium signaling pathway 28/498 265/7206 0.0252127143829 ko05162 Measles 15/498 120/7206 0.0265740952538 ko04015 Rap1 signaling pathway 29/498 278/7206 0.0288062642678 ko05323 Rheumatoid arthritis 12/498 89/7206 0.0314075063549 ko05144 Malaria 7/498 45/7206 0.0331948840407 ko00592 alpha-Linolenic acid metabolism 4/498 19/7206 0.0380582618637 ko04664 Fc epsilon RI signaling pathway 10/498 77/7206 0.0421452109449 ko00564 Glycerophospholipid metabolism 12/498 99/7206 0.0461233061343 ko05320 Autoimmune thyroid disease 5/498 29/7206 0.0462135362053 ko04670 Leukocyte transendothelial migration 17/498 151/7206 0.0489025025436