ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 34/245 145/7206 6.9762480878e-20 ko04110 Cell cycle 22/245 145/7206 2.74062675773e-09 ko04111 Cell cycle - yeast 17/245 90/7206 6.33840300234e-09 ko03013 RNA transport 18/245 166/7206 1.20626047965e-05 ko04330 Notch signaling pathway 10/245 62/7206 3.89157982539e-05 ko03008 Ribosome biogenesis in eukaryotes 11/245 79/7206 6.54881332179e-05 ko03015 mRNA surveillance pathway 12/245 93/7206 6.57817755451e-05 ko03410 Base excision repair 7/245 38/7206 0.000246686510753 ko04113 Meiosis - yeast 9/245 70/7206 0.000556635359189 ko04144 Endocytosis 2/245 342/7206 0.00106131120222 ko04024 cAMP signaling pathway 1/245 279/7206 0.00109345562526 ko00240 Pyrimidine metabolism 11/245 110/7206 0.00122191816882 ko04550 Signaling pathways regulating pluripotency of stem cells 14/245 165/7206 0.00141233835328 ko03460 Fanconi anemia pathway 7/245 51/7206 0.00155405658155 ko03030 DNA replication 6/245 38/7206 0.00160745077866 ko03020 RNA polymerase 5/245 29/7206 0.00265285537642 ko04310 Wnt signaling pathway 14/245 181/7206 0.00511599266081 ko04261 Adrenergic signaling in cardiomyocytes 1/245 205/7206 0.0104438723613 ko05166 HTLV-I infection 18/245 292/7206 0.0126528046826 ko04072 Phospholipase D signaling pathway 1/245 197/7206 0.0152007173857 ko04062 Chemokine signaling pathway 1/245 201/7206 0.0155756730152 ko05206 MicroRNAs in cancer 12/245 177/7206 0.0192972425889 ko04712 Circadian rhythm - plant 2/245 7/7206 0.0215941917634 ko04141 Protein processing in endoplasmic reticulum 1/245 184/7206 0.0218734411257 ko04530 Tight junction 2/245 228/7206 0.0250512785654 ko04120 Ubiquitin mediated proteolysis 10/245 138/7206 0.0269361099088 ko05217 Basal cell carcinoma 6/245 68/7206 0.0274549298 ko04910 Insulin signaling pathway 1/245 172/7206 0.0315019829802 ko04371 Apelin signaling pathway 1/245 177/7206 0.0322686033518 ko04022 cGMP-PKG signaling pathway 2/245 216/7206 0.0351308254817 ko04139 Mitophagy - yeast 4/245 37/7206 0.0357686546239 ko05202 Transcriptional misregulation in cancer 12/245 188/7206 0.0370155946143 ko04725 Cholinergic synapse 1/245 160/7206 0.0452571078006 ko03440 Homologous recombination 4/245 41/7206 0.0494213863894