ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	169/836	423/7206	8.23302127945e-55
ko05033	Nicotine addiction	48/836	56/7206	2.10452800022e-37
ko04724	Glutamatergic synapse	78/836	152/7206	3.68022148142e-34
ko05032	Morphine addiction	57/836	110/7206	1.87581708918e-25
ko04727	GABAergic synapse	56/836	110/7206	1.61131238129e-24
ko04728	Dopaminergic synapse	73/836	185/7206	4.68317253654e-23
ko04713	Circadian entrainment	61/836	136/7206	6.98002659826e-23
ko04723	Retrograde endocannabinoid signaling	68/836	175/7206	4.31449056576e-21
ko04024	cAMP signaling pathway	88/836	279/7206	7.52468009414e-20
ko04725	Cholinergic synapse	61/836	160/7206	1.55389389775e-18
ko04721	Synaptic vesicle cycle	40/836	80/7206	1.7876037688e-17
ko04911	Insulin secretion	46/836	117/7206	7.54296158848e-15
ko04921	Oxytocin signaling pathway	64/836	209/7206	5.32725158708e-14
ko04020	Calcium signaling pathway	74/836	265/7206	1.13505832946e-13
ko05031	Amphetamine addiction	38/836	91/7206	1.81301460086e-13
ko04742	Taste transduction	30/836	61/7206	3.55325384622e-13
ko04720	Long-term potentiation	38/836	99/7206	4.19745859205e-12
ko04726	Serotonergic synapse	46/836	137/7206	6.01483304624e-12
ko04261	Adrenergic signaling in cardiomyocytes	58/836	205/7206	3.95377822343e-11
ko05030	Cocaine addiction	29/836	73/7206	5.79782751659e-10
ko04744	Phototransduction	18/836	36/7206	1.43976731089e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/836	74/7206	2.0093683981e-08
ko04925	Aldosterone synthesis and secretion	33/836	105/7206	3.92025920844e-08
ko04970	Salivary secretion	30/836	95/7206	1.44748367539e-07
ko04060	Cytokine-cytokine receptor interaction	3/836	191/7206	2.41041756364e-07
ko04971	Gastric acid secretion	30/836	98/7206	3.1130286989e-07
ko03040	Spliceosome	1/836	145/7206	5.47783567776e-07
ko04745	Phototransduction - fly	16/836	38/7206	1.74928419107e-06
ko04010	MAPK signaling pathway	66/836	321/7206	2.63253224818e-06
ko05203	Viral carcinogenesis	10/836	277/7206	3.13795786352e-06
ko05164	Influenza A	3/836	167/7206	3.64471519428e-06
ko05168	Herpes simplex infection	4/836	182/7206	5.23742171649e-06
ko04514	Cell adhesion molecules (CAMs)	33/836	130/7206	1.01642659048e-05
ko04120	Ubiquitin mediated proteolysis	2/836	138/7206	1.10856039726e-05
ko04972	Pancreatic secretion	29/836	111/7206	1.73645991435e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/836	79/7206	1.86773573032e-05
ko04740	Olfactory transduction	23/836	80/7206	2.33943986804e-05
ko04022	cGMP-PKG signaling pathway	45/836	216/7206	8.20053996543e-05
ko05322	Systemic lupus erythematosus	4/836	151/7206	9.30360744795e-05
ko05169	Epstein-Barr virus infection	8/836	206/7206	0.000143222325459
ko04750	Inflammatory mediator regulation of TRP channels	29/836	122/7206	0.00014509120505
ko04072	Phospholipase D signaling pathway	41/836	197/7206	0.000162646987324
ko04621	NOD-like receptor signaling pathway	5/836	157/7206	0.000219791563132
ko04915	Estrogen signaling pathway	30/836	131/7206	0.000254339415496
ko04260	Cardiac muscle contraction	24/836	98/7206	0.000327790710214
ko04540	Gap junction	29/836	128/7206	0.000378793562377
ko04966	Collecting duct acid secretion	10/836	26/7206	0.000388530161717
ko05162	Measles	3/836	120/7206	0.000463388108932
ko05414	Dilated cardiomyopathy	26/836	112/7206	0.000471197615048
ko04550	Signaling pathways regulating pluripotency of stem cells	6/836	165/7206	0.000480848135876
ko04730	Long-term depression	20/836	78/7206	0.000493756711747
ko04350	TGF-beta signaling pathway	2/836	103/7206	0.000520917847216
ko04360	Axon guidance	45/836	233/7206	0.000527721000535
ko04141	Protein processing in endoplasmic reticulum	8/836	184/7206	0.000958542139295
ko04610	Complement and coagulation cascades	1/836	79/7206	0.00115393793971
ko03013	RNA transport	7/836	166/7206	0.0012860918215
ko04612	Antigen processing and presentation	1/836	77/7206	0.00178929881269
ko04140	Autophagy - animal	7/836	164/7206	0.00180455941744
ko05110	Vibrio cholerae infection	16/836	63/7206	0.0021635179381
ko04630	Jak-STAT signaling pathway	5/836	132/7206	0.00232708923037
ko04110	Cell cycle	6/836	145/7206	0.00238944452065
ko05161	Hepatitis B	8/836	173/7206	0.00239785805655
ko04626	Plant-pathogen interaction	7/836	18/7206	0.00276705372618
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/836	14/7206	0.00315694599604
ko05205	Proteoglycans in cancer	17/836	271/7206	0.00360993757424
ko04912	GnRH signaling pathway	25/836	122/7206	0.00395518782319
ko04014	Ras signaling pathway	48/836	279/7206	0.00416832271187
ko05215	Prostate cancer	4/836	111/7206	0.00429572292181
ko04976	Bile secretion	18/836	80/7206	0.00454400489007
ko04064	NF-kappa B signaling pathway	3/836	96/7206	0.00566662037992
ko00240	Pyrimidine metabolism	4/836	110/7206	0.00616529868872
ko04070	Phosphatidylinositol signaling system	23/836	112/7206	0.00658785656933
ko03008	Ribosome biogenesis in eukaryotes	2/836	79/7206	0.00709790942142
ko04510	Focal adhesion	15/836	240/7206	0.00733367093546
ko04330	Notch signaling pathway	1/836	62/7206	0.00826072141611
ko05140	Leishmaniasis	2/836	75/7206	0.0101360228171
ko04924	Renin secretion	18/836	86/7206	0.0105475542905
ko04146	Peroxisome	3/836	89/7206	0.011322453033
ko04015	Rap1 signaling pathway	46/836	278/7206	0.0126065086836
ko05034	Alcoholism	40/836	238/7206	0.0134466946169
ko05010	Alzheimer's disease	35/836	202/7206	0.013803715882
ko04214	Apoptosis - fly	2/836	72/7206	0.0146622997273
ko00512	Mucin type O-glycan biosynthesis	8/836	29/7206	0.0147065487096
ko04964	Proximal tubule bicarbonate reclamation	8/836	29/7206	0.0147065487096
ko05166	HTLV-I infection	21/836	292/7206	0.0149734290295
ko00310	Lysine degradation	2/836	73/7206	0.0150334593457
ko05410	Hypertrophic cardiomyopathy (HCM)	20/836	100/7206	0.0168002144484
ko04210	Apoptosis	11/836	180/7206	0.0178643524073
ko00480	Glutathione metabolism	1/836	55/7206	0.0179066788768
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/836	182/7206	0.0182216435821
ko04668	TNF signaling pathway	6/836	120/7206	0.0205111089575
ko05202	Transcriptional misregulation in cancer	12/836	188/7206	0.0207124343073
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/836	59/7206	0.0217580179099
ko04114	Oocyte meiosis	25/836	139/7206	0.0225776495128
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/836	15/7206	0.0230587573218
ko04150	mTOR signaling pathway	12/836	184/7206	0.0264800634926
ko05222	Small cell lung cancer	4/836	89/7206	0.0301475511066
ko01524	Platinum drug resistance	3/836	76/7206	0.0305202839959
ko04371	Apelin signaling pathway	30/836	177/7206	0.0316043354045
ko04916	Melanogenesis	25/836	142/7206	0.0329691151933
ko03420	Nucleotide excision repair	1/836	46/7206	0.0379385777273
ko05220	Chronic myeloid leukemia	4/836	85/7206	0.0411771074888
ko04657	IL-17 signaling pathway	4/836	87/7206	0.0415030225422
ko00330	Arginine and proline metabolism	2/836	61/7206	0.0422337389991
ko05206	MicroRNAs in cancer	12/836	177/7206	0.0427970768881
ko04218	Cellular senescence	12/836	177/7206	0.0427970768881