ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	143/695	423/7206	4.5155971405e-46
ko04724	Glutamatergic synapse	72/695	152/7206	5.00807349636e-34
ko05033	Nicotine addiction	41/695	56/7206	3.05763846027e-30
ko05032	Morphine addiction	50/695	110/7206	7.65343562639e-23
ko04727	GABAergic synapse	49/695	110/7206	6.29672946239e-22
ko04728	Dopaminergic synapse	64/695	185/7206	4.01391251297e-21
ko04723	Retrograde endocannabinoid signaling	61/695	175/7206	2.30095432783e-20
ko04713	Circadian entrainment	50/695	136/7206	5.37084936588e-18
ko04024	cAMP signaling pathway	72/695	279/7206	1.24349768356e-15
ko04721	Synaptic vesicle cycle	34/695	80/7206	8.15640035562e-15
ko04911	Insulin secretion	41/695	117/7206	3.91243087518e-14
ko04725	Cholinergic synapse	49/695	160/7206	5.05249964562e-14
ko04921	Oxytocin signaling pathway	56/695	209/7206	4.13405304956e-13
ko04020	Calcium signaling pathway	65/695	265/7206	4.4202908457e-13
ko04726	Serotonergic synapse	41/695	137/7206	1.43649544879e-11
ko04742	Taste transduction	25/695	61/7206	8.14868258941e-11
ko04261	Adrenergic signaling in cardiomyocytes	51/695	205/7206	9.67654919686e-11
ko05031	Amphetamine addiction	31/695	91/7206	1.23724056181e-10
ko04720	Long-term potentiation	32/695	99/7206	2.9206278947e-10
ko05030	Cocaine addiction	26/695	73/7206	1.31680082375e-09
ko04970	Salivary secretion	28/695	95/7206	3.77239918962e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	24/695	74/7206	4.68617600928e-08
ko04010	MAPK signaling pathway	60/695	321/7206	3.2432125572e-07
ko04971	Gastric acid secretion	26/695	98/7206	1.12422538585e-06
ko04972	Pancreatic secretion	28/695	111/7206	1.32566577308e-06
ko04072	Phospholipase D signaling pathway	41/695	197/7206	1.75216967038e-06
ko04925	Aldosterone synthesis and secretion	26/695	105/7206	4.58257694267e-06
ko03040	Spliceosome	1/695	145/7206	1.13583911084e-05
ko04514	Cell adhesion molecules (CAMs)	29/695	130/7206	1.36821340485e-05
ko05203	Viral carcinogenesis	8/695	277/7206	1.60866226947e-05
ko04260	Cardiac muscle contraction	23/695	98/7206	4.08398611144e-05
ko04060	Cytokine-cytokine receptor interaction	4/695	191/7206	5.25986976153e-05
ko05164	Influenza A	3/695	167/7206	8.67677670558e-05
ko05168	Herpes simplex infection	4/695	182/7206	0.000106876989843
ko04730	Long-term depression	19/695	78/7206	0.000110788027837
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	19/695	79/7206	0.000132987730683
ko04120	Ubiquitin mediated proteolysis	2/695	138/7206	0.000195935533806
ko04070	Phosphatidylinositol signaling system	23/695	112/7206	0.000489359087309
ko05414	Dilated cardiomyopathy	23/695	112/7206	0.000489359087309
ko04022	cGMP-PKG signaling pathway	37/695	216/7206	0.000582974629271
ko04540	Gap junction	25/695	128/7206	0.000667218434457
ko04915	Estrogen signaling pathway	25/695	131/7206	0.00080640455903
ko05162	Measles	2/695	120/7206	0.000853949042553
ko04621	NOD-like receptor signaling pathway	4/695	157/7206	0.000874703043457
ko05322	Systemic lupus erythematosus	4/695	151/7206	0.00121842442158
ko05205	Proteoglycans in cancer	12/695	271/7206	0.00158525395453
ko00240	Pyrimidine metabolism	2/695	110/7206	0.00177306527302
ko04350	TGF-beta signaling pathway	2/695	103/7206	0.0037045585222
ko04750	Inflammatory mediator regulation of TRP channels	22/695	122/7206	0.00459861830987
ko04924	Renin secretion	17/695	86/7206	0.00464564988407
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/695	182/7206	0.00478239034674
ko04510	Focal adhesion	11/695	240/7206	0.00511599315992
ko04612	Antigen processing and presentation	1/695	77/7206	0.00597927597323
ko04630	Jak-STAT signaling pathway	4/695	132/7206	0.00662863958134
ko04014	Ras signaling pathway	41/695	279/7206	0.00677941503618
ko04140	Autophagy - animal	6/695	164/7206	0.00678963112163
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/695	14/7206	0.00785830238075
ko05169	Epstein-Barr virus infection	9/695	206/7206	0.00787053510048
ko05215	Prostate cancer	3/695	111/7206	0.00861502134733
ko05161	Hepatitis B	7/695	173/7206	0.00862354090097
ko04966	Collecting duct acid secretion	7/695	26/7206	0.009673343449
ko04150	mTOR signaling pathway	8/695	184/7206	0.0108735948993
ko04141	Protein processing in endoplasmic reticulum	8/695	184/7206	0.0108735948993
ko04976	Bile secretion	15/695	80/7206	0.0114140998574
ko05231	Choline metabolism in cancer	22/695	134/7206	0.0114458185374
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/695	59/7206	0.0119299534637
ko04214	Apoptosis - fly	1/695	72/7206	0.0136673747091
ko04550	Signaling pathways regulating pluripotency of stem cells	7/695	165/7206	0.0154605265394
ko03013	RNA transport	7/695	166/7206	0.0156531310037
ko04015	Rap1 signaling pathway	39/695	278/7206	0.016604620732
ko05110	Vibrio cholerae infection	12/695	63/7206	0.0174711574306
ko04964	Proximal tubule bicarbonate reclamation	7/695	29/7206	0.0178146001155
ko04640	Hematopoietic cell lineage	1/695	64/7206	0.0187780107605
ko04064	NF-kappa B signaling pathway	3/695	96/7206	0.0231893543567
ko05410	Hypertrophic cardiomyopathy (HCM)	17/695	100/7206	0.0243619975232
ko04745	Phototransduction - fly	8/695	38/7206	0.0259449268891
ko04330	Notch signaling pathway	1/695	62/7206	0.0278861976287
ko00562	Inositol phosphate metabolism	15/695	89/7206	0.0285786711498
ko01524	Platinum drug resistance	2/695	76/7206	0.0310652025582
ko03008	Ribosome biogenesis in eukaryotes	2/695	79/7206	0.0321235185401
ko04740	Olfactory transduction	14/695	80/7206	0.0329454377279
ko05034	Alcoholism	33/695	238/7206	0.0329766243677
ko00650	Butanoate metabolism	6/695	26/7206	0.0339115380461
ko04930	Type II diabetes mellitus	10/695	54/7206	0.0356763161872
ko04218	Cellular senescence	9/695	177/7206	0.0381489426536
ko04918	Thyroid hormone synthesis	14/695	86/7206	0.0428757421329
ko00310	Lysine degradation	2/695	73/7206	0.044152834643
ko04146	Peroxisome	3/695	89/7206	0.0448096877931
ko05222	Small cell lung cancer	3/695	89/7206	0.0448096877931
ko05140	Leishmaniasis	2/695	75/7206	0.0456218241091
ko04110	Cell cycle	7/695	145/7206	0.0460830597864
ko02024	Quorum sensing	4/695	15/7206	0.0494767915507