ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	149/873	423/7206	1.0354049981e-37
ko04724	Glutamatergic synapse	78/873	152/7206	8.27998962026e-33
ko05032	Morphine addiction	60/873	110/7206	2.62285111985e-27
ko05033	Nicotine addiction	41/873	56/7206	3.0065735989e-26
ko04727	GABAergic synapse	57/873	110/7206	1.77956795605e-24
ko04721	Synaptic vesicle cycle	47/873	80/7206	1.64710471014e-23
ko04728	Dopaminergic synapse	75/873	185/7206	2.44086800184e-23
ko04723	Retrograde endocannabinoid signaling	72/873	175/7206	6.79261852134e-23
ko04713	Circadian entrainment	60/873	136/7206	4.36537814831e-21
ko04725	Cholinergic synapse	63/873	160/7206	5.65344030391e-19
ko04024	cAMP signaling pathway	83/873	279/7206	8.07975831304e-16
ko04742	Taste transduction	32/873	61/7206	1.84158383089e-14
ko04911	Insulin secretion	46/873	117/7206	3.89960867628e-14
ko04921	Oxytocin signaling pathway	65/873	209/7206	1.18984897704e-13
ko04261	Adrenergic signaling in cardiomyocytes	64/873	205/7206	1.52234216707e-13
ko04726	Serotonergic synapse	49/873	137/7206	4.1072729621e-13
ko04744	Phototransduction	22/873	36/7206	3.8009558666e-12
ko04020	Calcium signaling pathway	69/873	265/7206	2.68605581233e-10
ko04720	Long-term potentiation	36/873	99/7206	3.31451583363e-10
ko05031	Amphetamine addiction	34/873	91/7206	4.46264744456e-10
ko04925	Aldosterone synthesis and secretion	33/873	105/7206	1.12421657266e-07
ko05030	Cocaine addiction	26/873	73/7206	1.57602200257e-07
ko03040	Spliceosome	1/873	145/7206	2.2305338714e-07
ko04970	Salivary secretion	30/873	95/7206	3.7789139089e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/873	79/7206	9.28764115368e-07
ko04010	MAPK signaling pathway	69/873	321/7206	1.11736132691e-06
ko04260	Cardiac muscle contraction	29/873	98/7206	2.63187728097e-06
ko04971	Gastric acid secretion	29/873	98/7206	2.63187728097e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	24/873	74/7206	3.2609265874e-06
ko04514	Cell adhesion molecules (CAMs)	35/873	130/7206	3.70101688265e-06
ko04060	Cytokine-cytokine receptor interaction	5/873	191/7206	4.44734016904e-06
ko05414	Dilated cardiomyopathy	31/873	112/7206	6.12680966731e-06
ko05203	Viral carcinogenesis	12/873	277/7206	8.32304681332e-06
ko05168	Herpes simplex infection	5/873	182/7206	8.73118561987e-06
ko04120	Ubiquitin mediated proteolysis	3/873	138/7206	3.34359660789e-05
ko05322	Systemic lupus erythematosus	4/873	151/7206	4.34125083393e-05
ko04972	Pancreatic secretion	29/873	111/7206	4.59888310436e-05
ko04022	cGMP-PKG signaling pathway	47/873	216/7206	4.65731972049e-05
ko04072	Phospholipase D signaling pathway	44/873	197/7206	5.12864278917e-05
ko05164	Influenza A	5/873	167/7206	5.49785055605e-05
ko04915	Estrogen signaling pathway	32/873	131/7206	7.05201652994e-05
ko04621	NOD-like receptor signaling pathway	5/873	157/7206	0.000105922171627
ko04966	Collecting duct acid secretion	11/873	26/7206	0.000106412053353
ko04141	Protein processing in endoplasmic reticulum	7/873	184/7206	0.000129808125333
ko04961	Endocrine and other factor-regulated calcium reabsorption	18/873	59/7206	0.000134179656564
ko04740	Olfactory transduction	22/873	80/7206	0.000171943523182
ko03013	RNA transport	6/873	166/7206	0.000245543372935
ko05205	Proteoglycans in cancer	15/873	271/7206	0.000289508450378
ko04730	Long-term depression	21/873	78/7206	0.000314427367575
ko04360	Axon guidance	47/873	233/7206	0.000322914885625
ko04745	Phototransduction - fly	13/873	38/7206	0.000326898201798
ko05110	Vibrio cholerae infection	18/873	63/7206	0.00033491552422
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/873	14/7206	0.000593482553188
ko05410	Hypertrophic cardiomyopathy (HCM)	24/873	100/7206	0.00091955138532
ko04070	Phosphatidylinositol signaling system	26/873	112/7206	0.00105550704621
ko04612	Antigen processing and presentation	1/873	77/7206	0.00116593701336
ko05161	Hepatitis B	8/873	173/7206	0.00127810804969
ko04924	Renin secretion	21/873	86/7206	0.00130336266213
ko04110	Cell cycle	6/873	145/7206	0.00176370029008
ko04976	Bile secretion	19/873	80/7206	0.00304562232285
ko04750	Inflammatory mediator regulation of TRP channels	26/873	122/7206	0.00315331192682
ko05169	Epstein-Barr virus infection	12/873	206/7206	0.00327681763794
ko04014	Ras signaling pathway	50/873	279/7206	0.00363631918213
ko04540	Gap junction	27/873	128/7206	0.00365538733187
ko04064	NF-kappa B signaling pathway	3/873	96/7206	0.00395914674539
ko05162	Measles	5/873	120/7206	0.00437738267009
ko03008	Ribosome biogenesis in eukaryotes	2/873	79/7206	0.0048065620428
ko04640	Hematopoietic cell lineage	1/873	64/7206	0.00572321300409
ko04371	Apelin signaling pathway	34/873	177/7206	0.00681386193346
ko05140	Leishmaniasis	2/873	75/7206	0.00688270714987
ko04062	Chemokine signaling pathway	37/873	201/7206	0.00821222604188
ko05034	Alcoholism	42/873	238/7206	0.0111876681807
ko04930	Type II diabetes mellitus	13/873	54/7206	0.0115631744363
ko05215	Prostate cancer	5/873	111/7206	0.0116704297488
ko00480	Glutathione metabolism	1/873	55/7206	0.0117627439434
ko04217	Necroptosis	11/873	178/7206	0.0138798909685
ko04630	Jak-STAT signaling pathway	7/873	132/7206	0.0144467801626
ko00590	Arachidonic acid metabolism	1/873	52/7206	0.0173885570985
ko04918	Thyroid hormone synthesis	18/873	86/7206	0.0185126069941
ko04964	Proximal tubule bicarbonate reclamation	8/873	29/7206	0.0187849167502
ko05145	Toxoplasmosis	7/873	126/7206	0.018859476395
ko01524	Platinum drug resistance	3/873	76/7206	0.0215766101714
ko04146	Peroxisome	4/873	89/7206	0.0216440047704
ko04114	Oocyte meiosis	26/873	139/7206	0.0244770348832
ko00260	Glycine, serine and threonine metabolism	1/873	48/7206	0.025466610909
ko05219	Bladder cancer	1/873	48/7206	0.025466610909
ko04510	Focal adhesion	18/873	240/7206	0.026292114656
ko00240	Pyrimidine metabolism	6/873	110/7206	0.0268973427376
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/873	15/7206	0.0273626564973
ko00330	Arginine and proline metabolism	2/873	61/7206	0.0290311622319
ko04140	Autophagy - animal	11/873	164/7206	0.0290903342944
ko00310	Lysine degradation	3/873	73/7206	0.0300714230231
ko04923	Regulation of lipolysis in adipocytes	16/873	77/7206	0.0324937289095
ko04912	GnRH signaling pathway	23/873	122/7206	0.0342131065173
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/873	92/7206	0.0354214176499
ko03022	Basal transcription factors	1/873	44/7206	0.0374329621124
ko00071	Fatty acid degradation	1/873	45/7206	0.0374468146225
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/873	182/7206	0.0377223209392
ko03420	Nucleotide excision repair	1/873	46/7206	0.0380409951837
ko03018	RNA degradation	4/873	84/7206	0.041381741347
ko03320	PPAR signaling pathway	3/873	69/7206	0.041862969452
ko04214	Apoptosis - fly	3/873	72/7206	0.0430636284124
ko04270	Vascular smooth muscle contraction	27/873	154/7206	0.0449550756375
ko05010	Alzheimer's disease	34/873	202/7206	0.047977578565
ko04210	Apoptosis	13/873	180/7206	0.0480898016932
ko00562	Inositol phosphate metabolism	17/873	89/7206	0.0492084080685