ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	46/766	56/7206	6.10536128627e-36
ko04724	Glutamatergic synapse	70/766	152/7206	2.16206948873e-29
ko04080	Neuroactive ligand-receptor interaction	124/766	423/7206	2.75977695859e-28
ko04727	GABAergic synapse	57/766	110/7206	1.88844671762e-27
ko05032	Morphine addiction	57/766	110/7206	1.88844671762e-27
ko04723	Retrograde endocannabinoid signaling	64/766	175/7206	2.55503366396e-20
ko04744	Phototransduction	25/766	36/7206	6.1540268545e-17
ko04728	Dopaminergic synapse	61/766	185/7206	7.21137102115e-17
ko04725	Cholinergic synapse	53/766	160/7206	6.82815743235e-15
ko04713	Circadian entrainment	48/766	136/7206	8.34768639514e-15
ko04024	cAMP signaling pathway	70/766	279/7206	2.43047192758e-12
ko04721	Synaptic vesicle cycle	32/766	80/7206	5.69100738872e-12
ko04911	Insulin secretion	38/766	117/7206	9.80537351553e-11
ko04742	Taste transduction	25/766	61/7206	6.63008929338e-10
ko04020	Calcium signaling pathway	62/766	265/7206	1.27750887824e-09
ko04921	Oxytocin signaling pathway	50/766	209/7206	1.94540511248e-08
ko05030	Cocaine addiction	25/766	73/7206	5.01007518471e-08
ko05203	Viral carcinogenesis	6/766	277/7206	7.68295151079e-08
ko04261	Adrenergic signaling in cardiomyocytes	48/766	205/7206	9.65589548078e-08
ko05031	Amphetamine addiction	28/766	91/7206	1.09609757671e-07
ko04726	Serotonergic synapse	35/766	137/7206	6.7112577647e-07
ko04720	Long-term potentiation	28/766	99/7206	7.65892575834e-07
ko04740	Olfactory transduction	24/766	80/7206	1.48152258884e-06
ko03040	Spliceosome	1/766	145/7206	2.0321567688e-06
ko04010	MAPK signaling pathway	61/766	321/7206	4.38592505457e-06
ko04060	Cytokine-cytokine receptor interaction	5/766	191/7206	4.11627864028e-05
ko04970	Salivary secretion	24/766	95/7206	5.91368317937e-05
ko04925	Aldosterone synthesis and secretion	25/766	105/7206	8.24821813487e-05
ko05205	Proteoglycans in cancer	11/766	271/7206	0.000114187685868
ko04072	Phospholipase D signaling pathway	39/766	197/7206	0.000138609247814
ko04110	Cell cycle	3/766	145/7206	0.000174237161483
ko05014	Amyotrophic lateral sclerosis (ALS)	19/766	74/7206	0.000189874893409
ko04514	Cell adhesion molecules (CAMs)	28/766	130/7206	0.000241700577792
ko04972	Pancreatic secretion	25/766	111/7206	0.000245520373383
ko05164	Influenza A	5/766	167/7206	0.000329479864374
ko05168	Herpes simplex infection	6/766	182/7206	0.000358597485488
ko03013	RNA transport	5/766	166/7206	0.000476747877047
ko05169	Epstein-Barr virus infection	8/766	206/7206	0.000530832589814
ko04730	Long-term depression	19/766	78/7206	0.000543329304478
ko04260	Cardiac muscle contraction	22/766	98/7206	0.000683762023337
ko04621	NOD-like receptor signaling pathway	5/766	157/7206	0.000913865999029
ko04141	Protein processing in endoplasmic reticulum	7/766	184/7206	0.000982778751123
ko04022	cGMP-PKG signaling pathway	39/766	216/7206	0.00101406124038
ko05322	Systemic lupus erythematosus	5/766	151/7206	0.00126393049347
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/766	79/7206	0.0014245931657
ko04350	TGF-beta signaling pathway	2/766	103/7206	0.00177304562749
ko04964	Proximal tubule bicarbonate reclamation	9/766	29/7206	0.00232439352628
ko04612	Antigen processing and presentation	1/766	77/7206	0.0026474615894
ko03008	Ribosome biogenesis in eukaryotes	1/766	79/7206	0.00268392893606
ko05414	Dilated cardiomyopathy	22/766	112/7206	0.00464930623551
ko04120	Ubiquitin mediated proteolysis	5/766	138/7206	0.00474467401356
ko04146	Peroxisome	2/766	89/7206	0.00507850761931
ko05162	Measles	4/766	120/7206	0.00640966839377
ko04150	mTOR signaling pathway	9/766	184/7206	0.00743618685
ko04070	Phosphatidylinositol signaling system	21/766	112/7206	0.00820380522161
ko04915	Estrogen signaling pathway	24/766	131/7206	0.0091119964492
ko04976	Bile secretion	16/766	80/7206	0.0102952989669
ko05131	Shigellosis	2/766	82/7206	0.0105331149439
ko04137	Mitophagy - animal	2/766	82/7206	0.0105331149439
ko03018	RNA degradation	2/766	84/7206	0.0110395114728
ko04064	NF-kappa B signaling pathway	3/766	96/7206	0.0115657734928
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/766	14/7206	0.0118278775163
ko04930	Type II diabetes mellitus	12/766	54/7206	0.0120313479914
ko05200	Pathways in cancer	36/766	492/7206	0.0122535755642
ko04330	Notch signaling pathway	1/766	62/7206	0.0124117408602
ko04218	Cellular senescence	9/766	177/7206	0.012968676527
ko00562	Inositol phosphate metabolism	17/766	89/7206	0.0144165130389
ko04971	Gastric acid secretion	18/766	98/7206	0.0194044392028
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/766	182/7206	0.0201647194604
ko04630	Jak-STAT signaling pathway	6/766	132/7206	0.0213520166921
ko04924	Renin secretion	16/766	86/7206	0.0216204064181
ko05140	Leishmaniasis	2/766	75/7206	0.0217400849825
ko05133	Pertussis	3/766	87/7206	0.0225408267484
ko04217	Necroptosis	10/766	178/7206	0.0260812460337
ko00520	Amino sugar and nucleotide sugar metabolism	1/766	55/7206	0.0266550547949
ko00280	Valine, leucine and isoleucine degradation	1/766	54/7206	0.0266652513715
ko05145	Toxoplasmosis	6/766	126/7206	0.0280422710703
ko04140	Autophagy - animal	9/766	164/7206	0.0287377092748
ko04550	Signaling pathways regulating pluripotency of stem cells	9/766	165/7206	0.0288949529554
ko00512	Mucin type O-glycan biosynthesis	7/766	29/7206	0.0289031943125
ko05215	Prostate cancer	5/766	111/7206	0.0297275273341
ko04214	Apoptosis - fly	2/766	72/7206	0.0315366586472
ko04142	Lysosome	8/766	151/7206	0.0317108051347
ko05166	HTLV-I infection	20/766	292/7206	0.0325103242303
ko00230	Purine metabolism	30/766	194/7206	0.0329398238731
ko04978	Mineral absorption	9/766	40/7206	0.0329952385744
ko05161	Hepatitis B	10/766	173/7206	0.0335233123713
ko05231	Choline metabolism in cancer	22/766	134/7206	0.0335894226643
ko05224	Breast cancer	10/766	174/7206	0.0335958836095
ko00590	Arachidonic acid metabolism	1/766	52/7206	0.0392831362642
ko04923	Regulation of lipolysis in adipocytes	14/766	77/7206	0.0393975984169
ko00240	Pyrimidine metabolism	5/766	110/7206	0.0407322211693
ko04810	Regulation of actin cytoskeleton	18/766	264/7206	0.0413969395246
ko04510	Focal adhesion	16/766	240/7206	0.0426179814093
ko00910	Nitrogen metabolism	5/766	19/7206	0.044005434481
ko05217	Basal cell carcinoma	2/766	68/7206	0.0445009059348
ko05410	Hypertrophic cardiomyopathy (HCM)	17/766	100/7206	0.0480633171543