ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko03040	Spliceosome	87/728	145/7206	1.38055220205e-50
ko03013	RNA transport	65/728	166/7206	9.28278647014e-24
ko03030	DNA replication	30/728	38/7206	1.74629316918e-23
ko03008	Ribosome biogenesis in eukaryotes	41/728	79/7206	6.56817732616e-21
ko03050	Proteasome	33/728	54/7206	4.71723460701e-20
ko04080	Neuroactive ligand-receptor interaction	1/728	423/7206	7.78344443771e-19
ko04110	Cell cycle	54/728	145/7206	1.01607609663e-18
ko04111	Cell cycle - yeast	41/728	90/7206	3.17085506989e-18
ko03440	Homologous recombination	24/728	41/7206	2.55824003889e-14
ko03420	Nucleotide excision repair	25/728	46/7206	7.73091940283e-14
ko03430	Mismatch repair	17/728	22/7206	1.6201197844e-13
ko04113	Meiosis - yeast	28/728	70/7206	3.6437286063e-11
ko00240	Pyrimidine metabolism	36/728	110/7206	5.6434671154e-11
ko04024	cAMP signaling pathway	2/728	279/7206	8.17356047707e-11
ko03015	mRNA surveillance pathway	31/728	93/7206	7.4438722844e-10
ko03460	Fanconi anemia pathway	22/728	51/7206	8.39218495264e-10
ko04022	cGMP-PKG signaling pathway	1/728	216/7206	3.08464362843e-09
ko03410	Base excision repair	18/728	38/7206	4.69064840773e-09
ko03022	Basal transcription factors	19/728	44/7206	1.18622669424e-08
ko05010	Alzheimer's disease	1/728	202/7206	1.67059629773e-08
ko03020	RNA polymerase	15/728	29/7206	2.02975710692e-08
ko03018	RNA degradation	27/728	84/7206	2.28037020756e-08
ko04261	Adrenergic signaling in cardiomyocytes	2/728	205/7206	1.13588515704e-07
ko04725	Cholinergic synapse	1/728	160/7206	9.55411498622e-07
ko04810	Regulation of actin cytoskeleton	6/728	264/7206	1.06713120132e-06
ko04144	Endocytosis	11/728	342/7206	1.32924545274e-06
ko05169	Epstein-Barr virus infection	44/728	206/7206	1.47820612815e-06
ko04371	Apelin signaling pathway	2/728	177/7206	1.80626168473e-06
ko04723	Retrograde endocannabinoid signaling	2/728	175/7206	2.70814073594e-06
ko04072	Phospholipase D signaling pathway	3/728	197/7206	3.0194324832e-06
ko04724	Glutamatergic synapse	1/728	152/7206	3.48778023087e-06
ko04060	Cytokine-cytokine receptor interaction	3/728	191/7206	4.16782989843e-06
ko04062	Chemokine signaling pathway	4/728	201/7206	8.23979186658e-06
ko04611	Platelet activation	2/728	163/7206	8.70009178827e-06
ko00230	Purine metabolism	40/728	194/7206	9.04394588184e-06
ko04510	Focal adhesion	6/728	240/7206	9.14198558891e-06
ko04728	Dopaminergic synapse	3/728	185/7206	9.40164072518e-06
ko04726	Serotonergic synapse	1/728	137/7206	1.07125716514e-05
ko04713	Circadian entrainment	1/728	136/7206	1.71467257551e-05
ko05012	Parkinson's disease	2/728	155/7206	1.88486233211e-05
ko04630	Jak-STAT signaling pathway	1/728	132/7206	2.54970171661e-05
ko04151	PI3K-Akt signaling pathway	17/728	390/7206	2.92786656353e-05
ko03060	Protein export	10/728	23/7206	3.50154309187e-05
ko03450	Non-homologous end-joining	8/728	15/7206	3.52285133043e-05
ko00190	Oxidative phosphorylation	1/728	127/7206	3.65263137165e-05
ko04922	Glucagon signaling pathway	1/728	128/7206	3.78913600763e-05
ko04010	MAPK signaling pathway	13/728	321/7206	6.13025764129e-05
ko04911	Insulin secretion	1/728	117/7206	7.89318644442e-05
ko04621	NOD-like receptor signaling pathway	3/728	157/7206	8.22429148403e-05
ko04931	Insulin resistance	2/728	137/7206	8.63931169694e-05
ko05231	Choline metabolism in cancer	2/728	134/7206	0.000126220020228
ko04910	Insulin signaling pathway	4/728	172/7206	0.000154427489915
ko04727	GABAergic synapse	1/728	110/7206	0.00017483306562
ko05032	Morphine addiction	1/728	110/7206	0.00017483306562
ko05152	Tuberculosis	5/728	187/7206	0.000177190106779
ko04070	Phosphatidylinositol signaling system	1/728	112/7206	0.000183632524025
ko04514	Cell adhesion molecules (CAMs)	2/728	130/7206	0.000184389261938
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/728	182/7206	0.000245119254372
ko04659	Th17 cell differentiation	1/728	106/7206	0.000259430234449
ko00970	Aminoacyl-tRNA biosynthesis	13/728	44/7206	0.000273244295983
ko04152	AMPK signaling pathway	4/728	161/7206	0.000298439556947
ko04750	Inflammatory mediator regulation of TRP channels	2/728	122/7206	0.000391853068364
ko04015	Rap1 signaling pathway	12/728	278/7206	0.000502617590289
ko04014	Ras signaling pathway	12/728	279/7206	0.000507815231653
ko04650	Natural killer cell mediated cytotoxicity	1/728	97/7206	0.000569420812732
ko04720	Long-term potentiation	1/728	99/7206	0.000578174705734
ko05146	Amoebiasis	1/728	99/7206	0.000578174705734
ko04530	Tight junction	9/728	228/7206	0.000738023320546
ko04933	AGE-RAGE signaling pathway in diabetic complications	3/728	135/7206	0.000738927519729
ko05200	Pathways in cancer	29/728	492/7206	0.000824574221679
ko04670	Leukocyte transendothelial migration	4/728	151/7206	0.000871167044824
ko04974	Protein digestion and absorption	1/728	96/7206	0.000879451305695
ko05142	Chagas disease (American trypanosomiasis)	3/728	130/7206	0.00104088296246
ko04972	Pancreatic secretion	2/728	111/7206	0.00121527641155
ko00562	Inositol phosphate metabolism	1/728	89/7206	0.00124618314025
ko04071	Sphingolipid signaling pathway	5/728	162/7206	0.00132947190275
ko05145	Toxoplasmosis	3/728	126/7206	0.0014847838451
ko04540	Gap junction	3/728	128/7206	0.00154690328642
ko04925	Aldosterone synthesis and secretion	2/728	105/7206	0.00173403016076
ko05133	Pertussis	1/728	87/7206	0.00186411755456
ko04662	B cell receptor signaling pathway	1/728	88/7206	0.00191442875588
ko05160	Hepatitis C	5/728	153/7206	0.00252715832451
ko04068	FoxO signaling pathway	6/728	167/7206	0.00256350432029
ko04138	Autophagy - yeast	1/728	81/7206	0.00271411270811
ko04668	TNF signaling pathway	3/728	120/7206	0.00313239977262
ko04380	Osteoclast differentiation	4/728	134/7206	0.00334315626577
ko05167	Kaposi's sarcoma-associated herpesvirus infection	8/728	191/7206	0.0033726675607
ko00564	Glycerophospholipid metabolism	2/728	99/7206	0.00366711722561
ko04120	Ubiquitin mediated proteolysis	25/728	138/7206	0.00380091591896
ko04923	Regulation of lipolysis in adipocytes	1/728	77/7206	0.00399742061687
ko04141	Protein processing in endoplasmic reticulum	31/728	184/7206	0.0040333096045
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	1/728	79/7206	0.00404640884866
ko04721	Synaptic vesicle cycle	1/728	80/7206	0.00415006426561
ko04976	Bile secretion	1/728	80/7206	0.00415006426561
ko04722	Neurotrophin signaling pathway	6/728	160/7206	0.00485084863304
ko04658	Th1 and Th2 cell differentiation	2/728	96/7206	0.00540644569685
ko00010	Glycolysis / Gluconeogenesis	1/728	74/7206	0.00587764762403
ko05140	Leishmaniasis	1/728	75/7206	0.00595067661594
ko04066	HIF-1 signaling pathway	4/728	123/7206	0.00636553957166
ko04360	Axon guidance	12/728	233/7206	0.00783747230044
ko04217	Necroptosis	8/728	178/7206	0.008054205427
ko00514	Other types of O-glycan biosynthesis	8/728	30/7206	0.00813226301034
ko04912	GnRH signaling pathway	4/728	122/7206	0.00904716160153
ko04666	Fc gamma R-mediated phagocytosis	4/728	122/7206	0.00904716160153
ko04917	Prolactin signaling pathway	2/728	87/7206	0.0108632497916
ko04620	Toll-like receptor signaling pathway	3/728	100/7206	0.0117427580382
ko05161	Hepatitis B	8/728	173/7206	0.0144031104318
ko05034	Alcoholism	13/728	238/7206	0.0154656206047
ko05166	HTLV-I infection	42/728	292/7206	0.017034383491
ko05205	Proteoglycans in cancer	16/728	271/7206	0.0177168286309
ko04622	RIG-I-like receptor signaling pathway	1/728	62/7206	0.0185357998252
ko00561	Glycerolipid metabolism	1/728	63/7206	0.0187640990704
ko00600	Sphingolipid metabolism	1/728	63/7206	0.0187640990704
ko04914	Progesterone-mediated oocyte maturation	18/728	104/7206	0.0205984016898
ko05016	Huntington's disease	12/728	215/7206	0.0215485313192
ko04512	ECM-receptor interaction	2/728	79/7206	0.0221301890393
ko04660	T cell receptor signaling pathway	5/728	124/7206	0.0227486639756
ko04012	ErbB signaling pathway	4/728	109/7206	0.0233770342709
ko04712	Circadian rhythm - plant	3/728	7/7206	0.0263368919521
ko00510	N-Glycan biosynthesis	10/728	50/7206	0.0304624739778
ko04114	Oocyte meiosis	22/728	139/7206	0.0318052177848
ko04657	IL-17 signaling pathway	3/728	87/7206	0.0318092194795
ko04146	Peroxisome	3/728	89/7206	0.0320118752773
ko04391	Hippo signaling pathway - fly	3/728	90/7206	0.0324411035582
ko01521	EGFR tyrosine kinase inhibitor resistance	4/728	106/7206	0.0325886776928
ko04916	Melanogenesis	7/728	142/7206	0.034821051598
ko04919	Thyroid hormone signaling pathway	7/728	143/7206	0.0348480739125
ko05164	Influenza A	9/728	167/7206	0.0375876748453
ko04930	Type II diabetes mellitus	1/728	54/7206	0.0395091722744
ko05416	Viral myocarditis	1/728	55/7206	0.0400068454629
ko05132	Salmonella infection	4/728	98/7206	0.0426710247142
ko00670	One carbon pool by folate	5/728	20/7206	0.0445970435623
ko04213	Longevity regulating pathway - multiple species	3/728	86/7206	0.044966612378
ko04918	Thyroid hormone synthesis	3/728	86/7206	0.044966612378