ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	177/987	423/7206	1.1513573483e-49
ko04724	Glutamatergic synapse	76/987	152/7206	2.32266145971e-27
ko05033	Nicotine addiction	43/987	56/7206	1.05652801348e-26
ko04728	Dopaminergic synapse	74/987	185/7206	2.25310556205e-19
ko05032	Morphine addiction	53/987	110/7206	1.84449627785e-18
ko04721	Synaptic vesicle cycle	44/987	80/7206	2.23153742298e-18
ko04727	GABAergic synapse	52/987	110/7206	1.11876640121e-17
ko04713	Circadian entrainment	59/987	136/7206	1.17610822562e-17
ko04024	cAMP signaling pathway	91/987	279/7206	1.38897702198e-16
ko04725	Cholinergic synapse	63/987	160/7206	2.97903210119e-16
ko04723	Retrograde endocannabinoid signaling	64/987	175/7206	1.15309033039e-14
ko04911	Insulin secretion	49/987	117/7206	3.88901230918e-14
ko04020	Calcium signaling pathway	81/987	265/7206	4.09803116265e-13
ko04742	Taste transduction	32/987	61/7206	6.02129392079e-13
ko04921	Oxytocin signaling pathway	66/987	209/7206	1.24002459464e-11
ko04726	Serotonergic synapse	49/987	137/7206	4.14228717644e-11
ko04261	Adrenergic signaling in cardiomyocytes	63/987	205/7206	1.53208440514e-10
ko05031	Amphetamine addiction	37/987	91/7206	1.5350851382e-10
ko05203	Viral carcinogenesis	8/987	277/7206	6.56634059689e-10
ko04360	Axon guidance	65/987	233/7206	8.68267968918e-09
ko04720	Long-term potentiation	36/987	99/7206	9.92813388815e-09
ko04970	Salivary secretion	35/987	95/7206	1.0754626908e-08
ko03040	Spliceosome	1/987	145/7206	2.42159657243e-08
ko04060	Cytokine-cytokine receptor interaction	4/987	191/7206	2.6907632226e-08
ko04744	Phototransduction	18/987	36/7206	1.96531675021e-07
ko04120	Ubiquitin mediated proteolysis	2/987	138/7206	5.46450919534e-07
ko05168	Herpes simplex infection	5/987	182/7206	5.55497506062e-07
ko05164	Influenza A	4/987	167/7206	6.00708908211e-07
ko04022	cGMP-PKG signaling pathway	56/987	216/7206	1.52504838712e-06
ko05030	Cocaine addiction	26/987	73/7206	1.78048692154e-06
ko04010	MAPK signaling pathway	74/987	321/7206	3.88598894751e-06
ko03013	RNA transport	5/987	166/7206	5.41914800005e-06
ko05322	Systemic lupus erythematosus	4/987	151/7206	6.03823231428e-06
ko04514	Cell adhesion molecules (CAMs)	37/987	130/7206	7.68858408935e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	25/987	74/7206	8.33012697044e-06
ko04925	Aldosterone synthesis and secretion	32/987	105/7206	8.92668576043e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/987	79/7206	9.47615711047e-06
ko04971	Gastric acid secretion	30/987	98/7206	1.08546047443e-05
ko04745	Phototransduction - fly	16/987	38/7206	1.56572780289e-05
ko04621	NOD-like receptor signaling pathway	5/987	157/7206	1.63073060222e-05
ko04924	Renin secretion	26/987	86/7206	5.35179864505e-05
ko04730	Long-term depression	24/987	78/7206	8.10740397652e-05
ko04260	Cardiac muscle contraction	28/987	98/7206	8.90380624572e-05
ko04141	Protein processing in endoplasmic reticulum	9/987	184/7206	0.000124460074555
ko05169	Epstein-Barr virus infection	11/987	206/7206	0.000125310809779
ko03008	Ribosome biogenesis in eukaryotes	1/987	79/7206	0.00020260091145
ko04612	Antigen processing and presentation	1/987	77/7206	0.000314573295727
ko04740	Olfactory transduction	23/987	80/7206	0.000408599076131
ko04972	Pancreatic secretion	29/987	111/7206	0.000413731905251
ko05161	Hepatitis B	9/987	173/7206	0.000449959609237
ko04070	Phosphatidylinositol signaling system	29/987	112/7206	0.000464456232714
ko04630	Jak-STAT signaling pathway	6/987	132/7206	0.000805736606333
ko04064	NF-kappa B signaling pathway	3/987	96/7206	0.000844588115839
ko04110	Cell cycle	7/987	145/7206	0.000848438028318
ko04014	Ras signaling pathway	58/987	279/7206	0.000941816886452
ko04540	Gap junction	31/987	128/7206	0.00108360084644
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/987	14/7206	0.00126169052808
ko04966	Collecting duct acid secretion	10/987	26/7206	0.0014705032302
ko04146	Peroxisome	3/987	89/7206	0.00174651929774
ko05140	Leishmaniasis	2/987	75/7206	0.00208567235792
ko04750	Inflammatory mediator regulation of TRP channels	29/987	122/7206	0.0021313140613
ko05205	Proteoglycans in cancer	21/987	271/7206	0.00281927981166
ko05162	Measles	6/987	120/7206	0.00297255539121
ko04214	Apoptosis - fly	2/987	72/7206	0.00303978206187
ko05414	Dilated cardiomyopathy	27/987	112/7206	0.00316513905867
ko00480	Glutathione metabolism	1/987	55/7206	0.00503239489871
ko04072	Phospholipase D signaling pathway	41/987	197/7206	0.00594156372046
ko04961	Endocrine and other factor-regulated calcium reabsorption	16/987	59/7206	0.00637323917216
ko04626	Plant-pathogen interaction	7/987	18/7206	0.0071167186592
ko00590	Arachidonic acid metabolism	1/987	52/7206	0.00747980778216
ko00240	Pyrimidine metabolism	6/987	110/7206	0.00765253969427
ko04930	Type II diabetes mellitus	15/987	54/7206	0.00804591763442
ko04932	Non-alcoholic fatty liver disease (NAFLD)	13/987	182/7206	0.00832612462414
ko05166	HTLV-I infection	25/987	292/7206	0.00885625560606
ko04640	Hematopoietic cell lineage	2/987	64/7206	0.00940211045939
ko04668	TNF signaling pathway	7/987	120/7206	0.0101945678441
ko01524	Platinum drug resistance	3/987	76/7206	0.0106119042827
ko05219	Bladder cancer	1/987	48/7206	0.0110893208813
ko05410	Hypertrophic cardiomyopathy (HCM)	23/987	100/7206	0.01172935874
ko04964	Proximal tubule bicarbonate reclamation	9/987	29/7206	0.0126018713404
ko01200	Carbon metabolism	8/987	128/7206	0.0128835457121
ko00330	Arginine and proline metabolism	2/987	61/7206	0.013582192693
ko04140	Autophagy - animal	12/987	164/7206	0.01523877808
ko03018	RNA degradation	4/987	84/7206	0.0152866476211
ko00071	Fatty acid degradation	1/987	45/7206	0.0164249936624
ko00620	Pyruvate metabolism	1/987	46/7206	0.0164469829915
ko03420	Nucleotide excision repair	1/987	46/7206	0.0164469829915
ko05215	Prostate cancer	7/987	111/7206	0.0179455712871
ko04350	TGF-beta signaling pathway	6/987	103/7206	0.019637015482
ko03022	Basal transcription factors	1/987	44/7206	0.0248936934784
ko05110	Vibrio cholerae infection	15/987	63/7206	0.0261166640204
ko04722	Neurotrophin signaling pathway	32/987	160/7206	0.0262952699602
ko04657	IL-17 signaling pathway	5/987	87/7206	0.0272784684678
ko05321	Inflammatory bowel disease (IBD)	2/987	56/7206	0.0289615736611
ko04976	Bile secretion	18/987	80/7206	0.0315944022733
ko05145	Toxoplasmosis	9/987	126/7206	0.0351595710741
ko00980	Metabolism of xenobiotics by cytochrome P450	1/987	40/7206	0.0359003360615
ko04217	Necroptosis	15/987	178/7206	0.0359873644705
ko04210	Apoptosis	15/987	180/7206	0.0362114257011
ko05220	Chronic myeloid leukemia	5/987	85/7206	0.0373982350984
ko00310	Lysine degradation	4/987	73/7206	0.0390223518811
ko00380	Tryptophan metabolism	2/987	50/7206	0.0396134063744
ko04330	Notch signaling pathway	3/987	62/7206	0.0401670002873
ko04622	RIG-I-like receptor signaling pathway	3/987	62/7206	0.0401670002873
ko00561	Glycerolipid metabolism	3/987	63/7206	0.0406739692683
ko04142	Lysosome	12/987	151/7206	0.0410179322641
ko00562	Inositol phosphate metabolism	19/987	89/7206	0.0427016624959
ko04270	Vascular smooth muscle contraction	30/987	154/7206	0.0431198243407
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/987	15/7206	0.0439008561661
ko05206	MicroRNAs in cancer	15/987	177/7206	0.0454086479615