ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	148/972	423/7206	1.95249348218e-31
ko04724	Glutamatergic synapse	68/972	152/7206	1.78025561417e-21
ko05033	Nicotine addiction	36/972	56/7206	1.40313194433e-18
ko04721	Synaptic vesicle cycle	40/972	80/7206	3.67205708405e-15
ko04713	Circadian entrainment	53/972	136/7206	6.39069967389e-14
ko04727	GABAergic synapse	46/972	110/7206	1.44183972317e-13
ko04020	Calcium signaling pathway	81/972	265/7206	1.51864838639e-13
ko05032	Morphine addiction	45/972	110/7206	6.85850236629e-13
ko04728	Dopaminergic synapse	61/972	185/7206	6.28492267411e-12
ko04725	Cholinergic synapse	53/972	160/7206	1.66460745037e-10
ko04921	Oxytocin signaling pathway	62/972	209/7206	7.61511511401e-10
ko04723	Retrograde endocannabinoid signaling	54/972	175/7206	1.51944918028e-09
ko04911	Insulin secretion	41/972	117/7206	2.09978368072e-09
ko04024	cAMP signaling pathway	74/972	279/7206	3.20734975828e-09
ko04726	Serotonergic synapse	44/972	137/7206	1.38332138913e-08
ko05031	Amphetamine addiction	32/972	91/7206	1.13410181166e-07
ko03010	Ribosome	1/972	129/7206	2.9878187559e-07
ko04720	Long-term potentiation	33/972	99/7206	3.05779098821e-07
ko04970	Salivary secretion	32/972	95/7206	3.52507320396e-07
ko05322	Systemic lupus erythematosus	3/972	151/7206	1.4247071584e-06
ko03040	Spliceosome	3/972	145/7206	3.11222041347e-06
ko04261	Adrenergic signaling in cardiomyocytes	52/972	205/7206	3.58154587115e-06
ko04022	cGMP-PKG signaling pathway	54/972	216/7206	3.84852814946e-06
ko05168	Herpes simplex infection	6/972	182/7206	4.51546483074e-06
ko03013	RNA transport	5/972	166/7206	5.30551738742e-06
ko04744	Phototransduction	16/972	36/7206	5.49948545398e-06
ko05203	Viral carcinogenesis	14/972	277/7206	5.63319844014e-06
ko04742	Taste transduction	22/972	61/7206	6.80299078888e-06
ko04966	Collecting duct acid secretion	13/972	26/7206	8.57652860873e-06
ko04745	Phototransduction - fly	16/972	38/7206	1.2843364253e-05
ko05166	HTLV-I infection	17/972	292/7206	2.34613085085e-05
ko04730	Long-term depression	25/972	78/7206	2.95464414436e-05
ko04922	Glucagon signaling pathway	34/972	128/7206	6.65730703149e-05
ko04971	Gastric acid secretion	28/972	98/7206	7.15819583083e-05
ko04710	Circadian rhythm	16/972	43/7206	7.91105685709e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/972	74/7206	8.72798112142e-05
ko04925	Aldosterone synthesis and secretion	29/972	105/7206	0.00012363587195
ko05161	Hepatitis B	8/972	173/7206	0.000170584545864
ko04070	Phosphatidylinositol signaling system	30/972	112/7206	0.000210426809397
ko04630	Jak-STAT signaling pathway	5/972	132/7206	0.000273368262401
ko05164	Influenza A	8/972	167/7206	0.000327207156436
ko05162	Measles	4/972	120/7206	0.000357414342046
ko05140	Leishmaniasis	1/972	75/7206	0.000474546967125
ko05030	Cocaine addiction	21/972	73/7206	0.000750755561142
ko04110	Cell cycle	7/972	145/7206	0.00084066154264
ko04964	Proximal tubule bicarbonate reclamation	11/972	29/7206	0.000861502733434
ko04010	MAPK signaling pathway	64/972	321/7206	0.00104781751451
ko04626	Plant-pathogen interaction	8/972	18/7206	0.00133019882916
ko05110	Vibrio cholerae infection	18/972	63/7206	0.00133253362867
ko04060	Cytokine-cytokine receptor interaction	12/972	191/7206	0.00176439253941
ko04972	Pancreatic secretion	27/972	111/7206	0.00180404254466
ko04924	Renin secretion	22/972	86/7206	0.00223854411133
ko04014	Ras signaling pathway	55/972	279/7206	0.00305496605546
ko05169	Epstein-Barr virus infection	14/972	206/7206	0.00351249032634
ko04657	IL-17 signaling pathway	3/972	87/7206	0.00380387236707
ko04540	Gap junction	29/972	128/7206	0.00384862698044
ko04141	Protein processing in endoplasmic reticulum	12/972	184/7206	0.00416546760535
ko04360	Axon guidance	47/972	233/7206	0.0044411292614
ko04371	Apelin signaling pathway	37/972	177/7206	0.00520442390349
ko04621	NOD-like receptor signaling pathway	10/972	157/7206	0.00625118522938
ko00710	Carbon fixation in photosynthetic organisms	9/972	27/7206	0.00686309061194
ko04750	Inflammatory mediator regulation of TRP channels	27/972	122/7206	0.0073064149929
ko05200	Pathways in cancer	47/972	492/7206	0.00753698108673
ko04550	Signaling pathways regulating pluripotency of stem cells	11/972	165/7206	0.00762291445822
ko04960	Aldosterone-regulated sodium reabsorption	12/972	41/7206	0.00885460882757
ko00010	Glycolysis / Gluconeogenesis	18/972	74/7206	0.00980911442121
ko04620	Toll-like receptor signaling pathway	5/972	100/7206	0.0111737479185
ko04120	Ubiquitin mediated proteolysis	9/972	138/7206	0.0117479354323
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/972	92/7206	0.0131130742806
ko05016	Huntington's disease	17/972	215/7206	0.0145153103111
ko04260	Cardiac muscle contraction	22/972	98/7206	0.0159157108181
ko03420	Nucleotide excision repair	1/972	46/7206	0.0165138812775
ko05219	Bladder cancer	1/972	48/7206	0.0171411474648
ko04514	Cell adhesion molecules (CAMs)	27/972	130/7206	0.0191226563775
ko04350	TGF-beta signaling pathway	6/972	103/7206	0.0192859101137
ko04072	Phospholipase D signaling pathway	38/972	197/7206	0.0196808736026
ko04210	Apoptosis	14/972	180/7206	0.0201784664016
ko04810	Regulation of actin cytoskeleton	23/972	264/7206	0.0212790724663
ko04711	Circadian rhythm - fly	5/972	13/7206	0.0223281368157
ko05205	Proteoglycans in cancer	24/972	271/7206	0.0230324443056
ko05144	Malaria	1/972	45/7206	0.0253542171845
ko05206	MicroRNAs in cancer	14/972	177/7206	0.0256135009333
ko00280	Valine, leucine and isoleucine degradation	2/972	54/7206	0.0278762121862
ko05321	Inflammatory bowel disease (IBD)	2/972	56/7206	0.0283785470378
ko05130	Pathogenic Escherichia coli infection	4/972	77/7206	0.0285616497157
ko04740	Olfactory transduction	18/972	80/7206	0.0302409756983
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/972	14/7206	0.0309643377434
ko04064	NF-kappa B signaling pathway	6/972	96/7206	0.0346027678731
ko05133	Pertussis	5/972	87/7206	0.0381040292571
ko00680	Methane metabolism	9/972	34/7206	0.0394639265424
ko04330	Notch signaling pathway	3/972	62/7206	0.0403819387871
ko04622	RIG-I-like receptor signaling pathway	3/972	62/7206	0.0403819387871
ko00562	Inositol phosphate metabolism	19/972	89/7206	0.0404793619848
ko04930	Type II diabetes mellitus	13/972	54/7206	0.041950501277
ko05010	Alzheimer's disease	37/972	202/7206	0.0468616994453