ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04110	Cell cycle	59/542	145/7206	1.51367213527e-29
ko03040	Spliceosome	58/542	145/7206	1.40019666994e-28
ko03440	Homologous recombination	30/542	41/7206	1.31238505205e-25
ko04111	Cell cycle - yeast	43/542	90/7206	3.37280637404e-25
ko03460	Fanconi anemia pathway	31/542	51/7206	1.20756905388e-22
ko03030	DNA replication	27/542	38/7206	1.35934802631e-22
ko04113	Meiosis - yeast	31/542	70/7206	2.85294517279e-17
ko03013	RNA transport	47/542	166/7206	3.23287036606e-16
ko03430	Mismatch repair	17/542	22/7206	1.14988864564e-15
ko03008	Ribosome biogenesis in eukaryotes	28/542	79/7206	8.70243006938e-13
ko03420	Nucleotide excision repair	21/542	46/7206	2.03107987532e-12
ko00240	Pyrimidine metabolism	30/542	110/7206	2.46800225921e-10
ko03410	Base excision repair	17/542	38/7206	4.01204737387e-10
ko03018	RNA degradation	25/542	84/7206	1.07293043454e-09
ko04144	Endocytosis	3/542	342/7206	1.09501621288e-08
ko05322	Systemic lupus erythematosus	31/542	151/7206	1.87441790473e-07
ko03022	Basal transcription factors	14/542	44/7206	2.18331214343e-06
ko04151	PI3K-Akt signaling pathway	9/542	390/7206	7.08607360409e-06
ko04060	Cytokine-cytokine receptor interaction	1/542	191/7206	9.08358873591e-06
ko04010	MAPK signaling pathway	6/542	321/7206	1.05860273794e-05
ko04114	Oocyte meiosis	26/542	139/7206	1.1144107084e-05
ko04261	Adrenergic signaling in cardiomyocytes	2/542	205/7206	2.24795100232e-05
ko04723	Retrograde endocannabinoid signaling	1/542	175/7206	2.95705884577e-05
ko05010	Alzheimer's disease	2/542	202/7206	3.31745961931e-05
ko05166	HTLV-I infection	42/542	292/7206	3.53965893729e-05
ko04015	Rap1 signaling pathway	5/542	278/7206	3.63266171454e-05
ko04024	cAMP signaling pathway	5/542	279/7206	3.70672232698e-05
ko03015	mRNA surveillance pathway	19/542	93/7206	4.85047751691e-05
ko04914	Progesterone-mediated oocyte maturation	20/542	104/7206	7.63368326853e-05
ko04621	NOD-like receptor signaling pathway	1/542	157/7206	9.38801304217e-05
ko04728	Dopaminergic synapse	2/542	185/7206	0.000102013715005
ko05152	Tuberculosis	2/542	187/7206	0.000104555758343
ko04014	Ras signaling pathway	6/542	279/7206	0.000111720510572
ko04724	Glutamatergic synapse	1/542	152/7206	0.000138812180812
ko04142	Lysosome	1/542	151/7206	0.000138941989108
ko05012	Parkinson's disease	1/542	155/7206	0.000145275452889
ko04932	Non-alcoholic fatty liver disease (NAFLD)	2/542	182/7206	0.000153107714753
ko05203	Viral carcinogenesis	38/542	277/7206	0.000262138105143
ko04713	Circadian entrainment	1/542	136/7206	0.000445133280509
ko03450	Non-homologous end-joining	6/542	15/7206	0.000489539998997
ko05205	Proteoglycans in cancer	7/542	271/7206	0.000600614584997
ko04725	Cholinergic synapse	2/542	160/7206	0.000667081474576
ko04933	AGE-RAGE signaling pathway in diabetic complications	1/542	135/7206	0.000707854534824
ko04921	Oxytocin signaling pathway	4/542	209/7206	0.000714076728307
ko04218	Cellular senescence	26/542	177/7206	0.000794883987496
ko04120	Ubiquitin mediated proteolysis	22/542	138/7206	0.000805818992645
ko04270	Vascular smooth muscle contraction	2/542	154/7206	0.000953762972199
ko00190	Oxidative phosphorylation	1/542	127/7206	0.000975071441849
ko01200	Carbon metabolism	1/542	128/7206	0.000992268960148
ko04510	Focal adhesion	6/542	240/7206	0.00109883035338
ko05418	Fluid shear stress and atherosclerosis	3/542	173/7206	0.00117107253258
ko04912	GnRH signaling pathway	1/542	122/7206	0.00143783835045
ko04022	cGMP-PKG signaling pathway	5/542	216/7206	0.00146210166709
ko04911	Insulin secretion	1/542	117/7206	0.00211890851575
ko05034	Alcoholism	31/542	238/7206	0.00242878759832
ko04810	Regulation of actin cytoskeleton	8/542	264/7206	0.00274967517072
ko04726	Serotonergic synapse	2/542	137/7206	0.00281125165952
ko04727	GABAergic synapse	1/542	110/7206	0.00304243414813
ko05032	Morphine addiction	1/542	110/7206	0.00304243414813
ko04972	Pancreatic secretion	1/542	111/7206	0.00307049188092
ko04115	p53 signaling pathway	13/542	74/7206	0.0031518385818
ko04371	Apelin signaling pathway	4/542	177/7206	0.00362826417447
ko04915	Estrogen signaling pathway	2/542	131/7206	0.0040124654879
ko04659	Th17 cell differentiation	1/542	106/7206	0.00450977327981
ko05167	Kaposi's sarcoma-associated herpesvirus infection	5/542	191/7206	0.0051982669221
ko05145	Toxoplasmosis	2/542	126/7206	0.00574508410677
ko04971	Gastric acid secretion	1/542	98/7206	0.00648775285488
ko04520	Adherens junction	1/542	103/7206	0.00692689656892
ko04066	HIF-1 signaling pathway	2/542	123/7206	0.00844002447704
ko04660	T cell receptor signaling pathway	2/542	124/7206	0.00861915822336
ko04062	Chemokine signaling pathway	6/542	201/7206	0.00949729687079
ko04722	Neurotrophin signaling pathway	4/542	160/7206	0.00958648977973
ko04658	Th1 and Th2 cell differentiation	1/542	96/7206	0.00970404344528
ko04064	NF-kappa B signaling pathway	1/542	96/7206	0.00970404344528
ko04611	Platelet activation	4/542	163/7206	0.00974465397428
ko04650	Natural killer cell mediated cytotoxicity	1/542	97/7206	0.00991267624714
ko04072	Phospholipase D signaling pathway	6/542	197/7206	0.0128678996871
ko04931	Insulin resistance	3/542	137/7206	0.0129365262286
ko04662	B cell receptor signaling pathway	1/542	88/7206	0.013759846564
ko04146	Peroxisome	1/542	89/7206	0.0138241716081
ko05323	Rheumatoid arthritis	1/542	89/7206	0.0138241716081
ko05120	Epithelial cell signaling in Helicobacter pylori infection	1/542	92/7206	0.0145388485602
ko04530	Tight junction	8/542	228/7206	0.0151018169899
ko04360	Axon guidance	8/542	233/7206	0.0155041365495
ko04070	Phosphatidylinositol signaling system	2/542	112/7206	0.016960231964
ko05142	Chagas disease (American trypanosomiasis)	3/542	130/7206	0.0177670890578
ko04630	Jak-STAT signaling pathway	3/542	132/7206	0.0180945601809
ko04670	Leukocyte transendothelial migration	4/542	151/7206	0.0181749322602
ko03020	RNA polymerase	6/542	29/7206	0.0188591986583
ko04137	Mitophagy - animal	1/542	82/7206	0.0199961568777
ko01230	Biosynthesis of amino acids	1/542	85/7206	0.0204100936089
ko04924	Renin secretion	1/542	86/7206	0.0207900535829
ko05133	Pertussis	1/542	87/7206	0.021292195151
ko00310	Lysine degradation	11/542	73/7206	0.0228705539129
ko00230	Purine metabolism	23/542	194/7206	0.0265004332952
ko04664	Fc epsilon RI signaling pathway	1/542	77/7206	0.0289862554021
ko04512	ECM-receptor interaction	1/542	79/7206	0.0293412840826
ko04721	Synaptic vesicle cycle	1/542	80/7206	0.029769099742
ko04152	AMPK signaling pathway	5/542	161/7206	0.0326099026214
ko04720	Long-term potentiation	2/542	99/7206	0.0329588831729
ko04071	Sphingolipid signaling pathway	5/542	162/7206	0.0329822268497
ko04145	Phagosome	5/542	162/7206	0.0329822268497
ko04910	Insulin signaling pathway	6/542	172/7206	0.0398713418067
ko05030	Cocaine addiction	1/542	73/7206	0.042203843633
ko05134	Legionellosis	1/542	74/7206	0.0426630296004
ko05160	Hepatitis C	5/542	153/7206	0.0428499518774