ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 20/139 167/7206 4.22755676237e-11 ko05162 Measles 16/139 120/7206 8.68595617573e-10 ko04060 Cytokine-cytokine receptor interaction 19/139 191/7206 3.31704086355e-09 ko04621 NOD-like receptor signaling pathway 17/139 157/7206 6.56528846296e-09 ko05168 Herpes simplex infection 17/139 182/7206 6.11049926482e-08 ko04380 Osteoclast differentiation 14/139 134/7206 2.42538622444e-07 ko04217 Necroptosis 16/139 178/7206 2.62281001978e-07 ko05340 Primary immunodeficiency 7/139 30/7206 1.20027445998e-06 ko04658 Th1 and Th2 cell differentiation 11/139 96/7206 2.01312395093e-06 ko04650 Natural killer cell mediated cytotoxicity 11/139 97/7206 2.23359355695e-06 ko04620 Toll-like receptor signaling pathway 11/139 100/7206 3.02729886091e-06 ko05167 Kaposi's sarcoma-associated herpesvirus infection 15/139 191/7206 3.53080702746e-06 ko04660 T cell receptor signaling pathway 12/139 124/7206 4.14629322738e-06 ko05161 Hepatitis B 14/139 173/7206 5.37002780402e-06 ko04630 Jak-STAT signaling pathway 12/139 132/7206 7.96555823601e-06 ko05321 Inflammatory bowel disease (IBD) 8/139 56/7206 1.01937065503e-05 ko04064 NF-kappa B signaling pathway 10/139 96/7206 1.41645882834e-05 ko05145 Toxoplasmosis 11/139 126/7206 2.83260701423e-05 ko05160 Hepatitis C 12/139 153/7206 3.56501136745e-05 ko04210 Apoptosis 13/139 180/7206 3.99391147562e-05 ko05152 Tuberculosis 13/139 187/7206 5.94439795075e-05 ko04672 Intestinal immune network for IgA production 6/139 37/7206 6.57014036519e-05 ko05140 Leishmaniasis 8/139 75/7206 8.89672652913e-05 ko04622 RIG-I-like receptor signaling pathway 7/139 62/7206 0.000173338155727 ko04659 Th17 cell differentiation 9/139 106/7206 0.000191892816429 ko04662 B cell receptor signaling pathway 8/139 88/7206 0.000274651114205 ko04062 Chemokine signaling pathway 12/139 201/7206 0.000476504275441 ko04668 TNF signaling pathway 9/139 120/7206 0.000486552872062 ko05150 Staphylococcus aureus infection 5/139 36/7206 0.000578958395939 ko04612 Antigen processing and presentation 7/139 77/7206 0.000666662675803 ko04610 Complement and coagulation cascades 7/139 79/7206 0.000778316805752 ko05142 Chagas disease (American trypanosomiasis) 9/139 130/7206 0.000870793690652 ko05330 Allograft rejection 4/139 24/7206 0.00104361314556 ko04623 Cytosolic DNA-sensing pathway 5/139 41/7206 0.00106535864473 ko05133 Pertussis 7/139 87/7206 0.00138084153294 ko05166 HTLV-I infection 14/139 292/7206 0.00143961485486 ko05320 Autoimmune thyroid disease 4/139 29/7206 0.00216490199193 ko04664 Fc epsilon RI signaling pathway 6/139 77/7206 0.00356731291097 ko05332 Graft-versus-host disease 3/139 18/7206 0.00463509907258 ko05131 Shigellosis 6/139 82/7206 0.00487188101646 ko04670 Leukocyte transendothelial migration 8/139 151/7206 0.00861015821808 ko04666 Fc gamma R-mediated phagocytosis 7/139 122/7206 0.00907807095007 ko05132 Salmonella infection 6/139 98/7206 0.011410288207 ko04611 Platelet activation 8/139 163/7206 0.0132915538946 ko05134 Legionellosis 5/139 74/7206 0.0138132406611 ko05169 Epstein-Barr virus infection 9/139 206/7206 0.0178631164141 ko05416 Viral myocarditis 4/139 55/7206 0.0211651146314 ko04940 Type I diabetes mellitus 3/139 32/7206 0.0231631333026 ko04917 Prolactin signaling pathway 5/139 87/7206 0.026017404785 ko05323 Rheumatoid arthritis 5/139 89/7206 0.0283570859895 ko04145 Phagosome 7/139 162/7206 0.0368067880254 ko04514 Cell adhesion molecules (CAMs) 6/139 130/7206 0.0394078704545 ko04933 AGE-RAGE signaling pathway in diabetic complications 6/139 135/7206 0.0459720565302