ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04744	Phototransduction	25/450	36/7206	1.28793375948e-22
ko04727	GABAergic synapse	27/450	110/7206	4.07040592993e-10
ko05033	Nicotine addiction	18/450	56/7206	3.46258498054e-09
ko05032	Morphine addiction	25/450	110/7206	1.01335721113e-08
ko04721	Synaptic vesicle cycle	21/450	80/7206	1.03213889644e-08
ko04724	Glutamatergic synapse	30/450	152/7206	1.15063468075e-08
ko04966	Collecting duct acid secretion	11/450	26/7206	1.63817873355e-07
ko04713	Circadian entrainment	25/450	136/7206	8.10746090891e-07
ko00830	Retinol metabolism	13/450	42/7206	8.87322483538e-07
ko04723	Retrograde endocannabinoid signaling	28/450	175/7206	3.24317199739e-06
ko04911	Insulin secretion	20/450	117/7206	3.14432930664e-05
ko05203	Viral carcinogenesis	3/450	277/7206	3.52213698208e-05
ko05169	Epstein-Barr virus infection	1/450	206/7206	4.89893130944e-05
ko04974	Protein digestion and absorption	17/450	96/7206	7.77550831488e-05
ko04728	Dopaminergic synapse	26/450	185/7206	8.01196749504e-05
ko04726	Serotonergic synapse	21/450	137/7206	0.0001051372282
ko04080	Neuroactive ligand-receptor interaction	45/450	423/7206	0.000374671499218
ko05110	Vibrio cholerae infection	12/450	63/7206	0.000436733755886
ko04614	Renin-angiotensin system	6/450	18/7206	0.000558304294632
ko04060	Cytokine-cytokine receptor interaction	2/450	191/7206	0.000693212278222
ko04141	Protein processing in endoplasmic reticulum	2/450	184/7206	0.000995196014017
ko04810	Regulation of actin cytoskeleton	5/450	264/7206	0.00108868913254
ko05166	HTLV-I infection	6/450	292/7206	0.00115818156366
ko03040	Spliceosome	1/450	145/7206	0.00149418618544
ko04970	Salivary secretion	14/450	95/7206	0.00214947189906
ko05205	Proteoglycans in cancer	6/450	271/7206	0.00294253567063
ko05164	Influenza A	2/450	167/7206	0.00300683741619
ko04976	Bile secretion	12/450	80/7206	0.00376077656863
ko05031	Amphetamine addiction	13/450	91/7206	0.00403083233419
ko04621	NOD-like receptor signaling pathway	2/450	157/7206	0.00418641103798
ko05145	Toxoplasmosis	1/450	126/7206	0.00465889070094
ko05030	Cocaine addiction	11/450	73/7206	0.00524664111709
ko05322	Systemic lupus erythematosus	2/450	151/7206	0.0059720375597
ko00230	Purine metabolism	22/450	194/7206	0.00607472902368
ko05162	Measles	1/450	120/7206	0.00680024800472
ko04217	Necroptosis	3/450	178/7206	0.00687498697481
ko04725	Cholinergic synapse	19/450	160/7206	0.00703535262455
ko04024	cAMP signaling pathway	29/450	279/7206	0.0073966384854
ko04730	Long-term depression	11/450	78/7206	0.00866970628264
ko04972	Pancreatic secretion	14/450	111/7206	0.00962776674849
ko05161	Hepatitis B	3/450	173/7206	0.00977153722697
ko04720	Long-term potentiation	13/450	99/7206	0.00988239157897
ko04978	Mineral absorption	7/450	40/7206	0.0109235872246
ko05323	Rheumatoid arthritis	12/450	89/7206	0.0120274079624
ko04742	Taste transduction	9/450	61/7206	0.0127041370459
ko05120	Epithelial cell signaling in Helicobacter pylori infection	12/450	92/7206	0.0140771426617
ko05215	Prostate cancer	1/450	111/7206	0.0151573602316
ko04710	Circadian rhythm	7/450	43/7206	0.0160806898377
ko04380	Osteoclast differentiation	2/450	134/7206	0.017348758072
ko00340	Histidine metabolism	5/450	25/7206	0.0174392846524
ko05168	Herpes simplex infection	4/450	182/7206	0.0187348034069
ko04971	Gastric acid secretion	12/450	98/7206	0.0201654357552
ko04620	Toll-like receptor signaling pathway	1/450	100/7206	0.020712745316
ko04924	Renin secretion	11/450	86/7206	0.0212331364938
ko04350	TGF-beta signaling pathway	1/450	103/7206	0.0213111641028
ko04022	cGMP-PKG signaling pathway	22/450	216/7206	0.0213914514542
ko00965	Betalain biosynthesis	2/450	4/7206	0.0214586985343
ko00290	Valine, leucine and isoleucine biosynthesis	2/450	4/7206	0.0214586985343
ko04925	Aldosterone synthesis and secretion	13/450	105/7206	0.0221336381338
ko04660	T cell receptor signaling pathway	2/450	124/7206	0.0239880739143
ko05224	Breast cancer	4/450	174/7206	0.0253327174818
ko04514	Cell adhesion molecules (CAMs)	15/450	130/7206	0.0253865068385
ko05206	MicroRNAs in cancer	4/450	177/7206	0.0258639129403
ko04745	Phototransduction - fly	6/450	38/7206	0.028836230979
ko04510	Focal adhesion	7/450	240/7206	0.0288683811362
ko04658	Th1 and Th2 cell differentiation	1/450	96/7206	0.0305600523349
ko04064	NF-kappa B signaling pathway	1/450	96/7206	0.0305600523349
ko05016	Huntington's disease	6/450	215/7206	0.0309314040977
ko04740	Olfactory transduction	10/450	80/7206	0.031987510648
ko02010	ABC transporters	6/450	39/7206	0.0323503599817
ko04016	MAPK signaling pathway - plant	4/450	20/7206	0.0327160903956
ko04668	TNF signaling pathway	2/450	120/7206	0.0340908617089
ko03013	RNA transport	4/450	166/7206	0.0342404592158
ko00380	Tryptophan metabolism	7/450	50/7206	0.034354378282
ko00190	Oxidative phosphorylation	14/450	127/7206	0.0384731106235
ko00140	Steroid hormone biosynthesis	6/450	41/7206	0.0401851725076
ko05200	Pathways in cancer	20/450	492/7206	0.0419297027741
ko01230	Biosynthesis of amino acids	10/450	85/7206	0.0421789784478
ko05210	Colorectal cancer	1/450	86/7206	0.0431273607427
ko04711	Circadian rhythm - fly	3/450	13/7206	0.0432814972329
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/450	182/7206	0.043715631411
ko00983	Drug metabolism - other enzymes	6/450	42/7206	0.0445157100194
ko04973	Carbohydrate digestion and absorption	6/450	42/7206	0.0445157100194
ko04940	Type I diabetes mellitus	5/450	32/7206	0.0463112896075
ko04140	Autophagy - animal	4/450	164/7206	0.0474892837498
ko00010	Glycolysis / Gluconeogenesis	9/450	74/7206	0.0481150403191