ko pathway ratio_in_study ratio_in_pop p_value ko04217 Necroptosis 28/171 178/7206 6.2119493298e-16 ko04621 NOD-like receptor signaling pathway 25/171 157/7206 1.95010816158e-14 ko04060 Cytokine-cytokine receptor interaction 27/171 191/7206 3.33043968659e-14 ko05340 Primary immunodeficiency 13/171 30/7206 4.04255172398e-14 ko05162 Measles 21/171 120/7206 4.12828711795e-13 ko05164 Influenza A 24/171 167/7206 7.0087064444e-13 ko05168 Herpes simplex infection 24/171 182/7206 4.74277637326e-12 ko04612 Antigen processing and presentation 16/171 77/7206 1.9475237596e-11 ko04630 Jak-STAT signaling pathway 20/171 132/7206 2.48062205531e-11 ko05321 Inflammatory bowel disease (IBD) 14/171 56/7206 2.57220904618e-11 ko04659 Th17 cell differentiation 18/171 106/7206 3.67928859561e-11 ko05145 Toxoplasmosis 19/171 126/7206 8.8002668797e-11 ko04650 Natural killer cell mediated cytotoxicity 16/171 97/7206 7.48659176998e-10 ko05330 Allograft rejection 9/171 24/7206 1.86251749731e-09 ko04380 Osteoclast differentiation 18/171 134/7206 1.9688806874e-09 ko04658 Th1 and Th2 cell differentiation 15/171 96/7206 5.67387637375e-09 ko05320 Autoimmune thyroid disease 9/171 29/7206 1.28805410571e-08 ko05152 Tuberculosis 20/171 187/7206 1.35703056202e-08 ko05140 Leishmaniasis 13/171 75/7206 1.6895989695e-08 ko04064 NF-kappa B signaling pathway 14/171 96/7206 4.64750581374e-08 ko05332 Graft-versus-host disease 7/171 18/7206 9.57241000439e-08 ko04620 Toll-like receptor signaling pathway 13/171 100/7206 5.66669426703e-07 ko05167 Kaposi's sarcoma-associated herpesvirus infection 17/171 191/7206 2.43676000183e-06 ko05161 Hepatitis B 16/171 173/7206 2.96492999648e-06 ko03050 Proteasome 9/171 54/7206 4.10678324131e-06 ko04940 Type I diabetes mellitus 7/171 32/7206 7.64536516593e-06 ko04640 Hematopoietic cell lineage 9/171 64/7206 1.73501176197e-05 ko04062 Chemokine signaling pathway 16/171 201/7206 2.0315036775e-05 ko04660 T cell receptor signaling pathway 12/171 124/7206 3.43658185493e-05 ko05310 Asthma 5/171 17/7206 3.48499712122e-05 ko05133 Pertussis 10/171 87/7206 3.59629759958e-05 ko05160 Hepatitis C 13/171 153/7206 6.39670435605e-05 ko05144 Malaria 7/171 45/7206 7.94824990306e-05 ko04622 RIG-I-like receptor signaling pathway 8/171 62/7206 9.68323316397e-05 ko04672 Intestinal immune network for IgA production 6/171 37/7206 0.000206429348414 ko05142 Chagas disease (American trypanosomiasis) 11/171 130/7206 0.000245670519136 ko04145 Phagosome 12/171 162/7206 0.000444154889155 ko04210 Apoptosis 12/171 180/7206 0.00113458556759 ko05323 Rheumatoid arthritis 8/171 89/7206 0.00117543144886 ko05169 Epstein-Barr virus infection 13/171 206/7206 0.0011787461617 ko05150 Staphylococcus aureus infection 5/171 36/7206 0.0014740651736 ko05416 Viral myocarditis 6/171 55/7206 0.00180971891906 ko04668 TNF signaling pathway 9/171 120/7206 0.00211786703173 ko04623 Cytosolic DNA-sensing pathway 5/171 41/7206 0.00266350853632 ko04514 Cell adhesion molecules (CAMs) 9/171 130/7206 0.00364552873466 ko04662 B cell receptor signaling pathway 7/171 88/7206 0.00473704998397 ko05143 African trypanosomiasis 4/171 32/7206 0.00655442057911 ko04080 Neuroactive ligand-receptor interaction 3/171 423/7206 0.0192550827477 ko05166 HTLV-I infection 13/171 292/7206 0.0277421740727 ko05146 Amoebiasis 6/171 99/7206 0.0298955776318 ko04664 Fc epsilon RI signaling pathway 5/171 77/7206 0.0356150336557 ko05131 Shigellosis 5/171 82/7206 0.0448130606487 ko04530 Tight junction 1/171 228/7206 0.0452777966768