ko pathway ratio_in_study ratio_in_pop p_value ko04713 Circadian entrainment 4/17 136/7206 0.000238700893612 ko04724 Glutamatergic synapse 4/17 152/7206 0.000365600333836 ko05030 Cocaine addiction 3/17 73/7206 0.000612567154302 ko04080 Neuroactive ligand-receptor interaction 5/17 423/7206 0.00233723275491 ko05033 Nicotine addiction 2/17 56/7206 0.0074859456269 ko05014 Amyotrophic lateral sclerosis (ALS) 2/17 74/7206 0.0128068220212 ko05034 Alcoholism 3/17 238/7206 0.0171714811057 ko05031 Amphetamine addiction 2/17 91/7206 0.0189660113679 ko04720 Long-term potentiation 2/17 99/7206 0.0222208499133 ko04020 Calcium signaling pathway 3/17 265/7206 0.0228163325762 ko04024 cAMP signaling pathway 3/17 279/7206 0.0261028165019 ko04070 Phosphatidylinositol signaling system 2/17 112/7206 0.0279678387263