ko pathway ratio_in_study ratio_in_pop p_value ko00350 Tyrosine metabolism 10/170 33/7206 2.37498847205e-09 ko00643 Styrene degradation 4/170 4/7206 2.99189271991e-07 ko00360 Phenylalanine metabolism 6/170 17/7206 1.57478846778e-06 ko00140 Steroid hormone biosynthesis 8/170 41/7206 4.002947824e-06 ko03320 PPAR signaling pathway 10/170 69/7206 4.19029522176e-06 ko00120 Primary bile acid biosynthesis 6/170 20/7206 4.64976885197e-06 ko00100 Steroid biosynthesis 6/170 21/7206 6.38312605995e-06 ko00983 Drug metabolism - other enzymes 7/170 42/7206 4.83236416667e-05 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/170 4/7206 5.07206435886e-05 ko00380 Tryptophan metabolism 7/170 50/7206 0.000152658821162 ko04060 Cytokine-cytokine receptor interaction 14/170 191/7206 0.000155643793377 ko04974 Protein digestion and absorption 9/170 96/7206 0.000408531048445 ko04976 Bile secretion 8/170 80/7206 0.000555826070946 ko00592 alpha-Linolenic acid metabolism 4/170 19/7206 0.000878359417714 ko00590 Arachidonic acid metabolism 6/170 52/7206 0.00130741518927 ko00950 Isoquinoline alkaloid biosynthesis 3/170 10/7206 0.00137015851771 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 3/170 11/7206 0.00185145723506 ko04080 Neuroactive ligand-receptor interaction 2/170 423/7206 0.00430558815495 ko04972 Pancreatic secretion 8/170 111/7206 0.00456960236028 ko04146 Peroxisome 7/170 89/7206 0.00488284723391 ko05204 Chemical carcinogenesis 5/170 48/7206 0.00519705365613 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/170 5/7206 0.00527996436099 ko04975 Fat digestion and absorption 4/170 35/7206 0.00885203637857 ko00480 Glutathione metabolism 5/170 55/7206 0.00925427317963 ko02010 ABC transporters 4/170 39/7206 0.0129307193951 ko01212 Fatty acid metabolism 5/170 60/7206 0.0132274340146 ko05200 Pathways in cancer 4/170 492/7206 0.0134058855664 ko00980 Metabolism of xenobiotics by cytochrome P450 4/170 40/7206 0.014109310331 ko00740 Riboflavin metabolism 2/170 8/7206 0.0141100635168 ko00330 Arginine and proline metabolism 5/170 61/7206 0.0141410328101 ko04024 cAMP signaling pathway 1/170 279/7206 0.0150374448891 ko04015 Rap1 signaling pathway 1/170 278/7206 0.0150479728026 ko05166 HTLV-I infection 1/170 292/7206 0.0156990101844 ko00830 Retinol metabolism 4/170 42/7206 0.0166657320198 ko00627 Aminobenzoate degradation 2/170 9/7206 0.017862661232 ko01040 Biosynthesis of unsaturated fatty acids 3/170 25/7206 0.0202689250954 ko00071 Fatty acid degradation 4/170 45/7206 0.0210138268824 ko00920 Sulfur metabolism 2/170 10/7206 0.0219857869106 ko05203 Viral carcinogenesis 1/170 277/7206 0.023042867399 ko00401 Novobiocin biosynthesis 1/170 1/7206 0.0235914515681 ko04064 NF-kappa B signaling pathway 6/170 96/7206 0.0255422360792 ko00260 Glycine, serine and threonine metabolism 4/170 48/7206 0.0259984379746 ko05340 Primary immunodeficiency 3/170 30/7206 0.0328533616213 ko04010 MAPK signaling pathway 2/170 321/7206 0.0356086634187 ko04630 Jak-STAT signaling pathway 7/170 132/7206 0.036205348341 ko04151 PI3K-Akt signaling pathway 3/170 390/7206 0.0367431183301 ko04380 Osteoclast differentiation 7/170 134/7206 0.0387989677825 ko04360 Axon guidance 1/170 233/7206 0.0455293210309 ko05034 Alcoholism 1/170 238/7206 0.0463716259825 ko00500 Starch and sucrose metabolism 3/170 35/7206 0.0486570714628